• 1. Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, P.R.China;
  • 2. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, P.R.China;
  • 3. Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, P.R.China;
  • 4. International Evidence-based Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, P.R.China;
ZHAO Chen, Email: zyyzc2007@163.com; SHANG Hongcai, Email: shanghongcai@foxmail.com
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The prominent feature and form of clinical diagnosis and treatment of traditional Chinese medicine is individualization, which has generated difficulty for clinical evaluation and has restricted the production of high-level evidence for traditional Chinese medicine for a long time. Based on the complexity and dynamics of individualized information under the characteristics of time and space, this paper references the theory of space-time of system science to analyze the individualized data of diagnosis and treatment of traditional Chinese medicine and summarizes the concept of the long time course for clinical evaluation. Based on the concept of the long time course, this paper starts with the origin of clinical evaluation, which is the construction of clinical problem elements named PICO, introduces dynamic evaluation factors, explores the construction of individualized dynamic evaluation method of traditional Chinese medicine, and provides demonstration and examples for the design and implementation of individualized clinical research in future.

Citation: SHI Zhaofeng, ZHAO Chen, HU Jiayuan, JIANG Yin, ZHANG Xiaoyu, SUN Yang, SHANG Hongcai. Construction of the evaluation method of personalized dynamic efficacy for traditional Chinese medicine from the perspective of the long time course. Chinese Journal of Evidence-Based Medicine, 2020, 20(12): 1373-1378. doi: 10.7507/1672-2531.202009011 Copy

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