Correlation between Coronary Plaque Composition and Degree of Stenosis by 128-slice Spiral Computed Tomography Coronary Angiography in Patients with Coronary Heart Disease_West China Medical Journal

Authors：

ZUO Wen , CHEN Zhubi , WANG Jianqiu , LUO Ying , HAN Wenbin , HE Jun.

Department of Radiology, the First People’s Hospital of Yibin, Yibin, Sichuan 644000, P. R. China;

Corresponding author：

Keywords：

冠状动脉狭窄; 冠状动脉粥样硬化斑块; 体层摄影术，X线计算机

DOI：

10.7507/1002-0179.20130493

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目的　应用128层螺旋CT冠状动脉成像，探讨冠状动脉不同成分斑块与狭窄程度的诊断价值。方法　对2010年3月－2012年10月150例临床拟诊冠心病及确诊冠心病患者的128层螺旋CT冠状动脉成像检查，冠状动脉影像表现由两位心血管CT诊断医师独立判断冠状动脉斑块成分及测量冠状动脉狭窄程度。应用Circulation血管分析软件，分析冠状动脉斑块成分与狭窄程度之间的相关性。结果　150例患者中，共发现319处斑块，其中软斑块104处，纤维、混合斑块103处，钙化斑块112处。冠状动脉轻度狭窄114处中，钙化斑块86处（75.4%）；冠状动脉中度狭窄113处中，纤维、混合斑块75处（66.3%）；冠状动脉重度狭窄92处中，软斑块68处（73.9%）。结论　128层螺旋CT冠状动脉成像能够有效检测患者冠状动脉斑块的成分及准确判断冠状动脉狭窄程度。

Citation： ZUO Wen,CHEN Zhubi,WANG Jianqiu,LUO Ying,HAN Wenbin,HE Jun.. Correlation between Coronary Plaque Composition and Degree of Stenosis by 128-slice Spiral Computed Tomography Coronary Angiography in Patients with Coronary Heart Disease. West China Medical Journal, 2013, 28(10): 1564-1566. doi: 10.7507/1002-0179.20130493 Copy

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1. 　Pugliese F, Moler NRA, Runza G, et al. Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris[J]. Eur Radiol, 2006, 16(3): 575．.
2. 　Johnson TR, Nikolaou K, Busch S, et al. Diagnostic accuracy of dual-source computed tomography in the diagnosis of coronary artery disease[J]. Invest Radiol, 2007, 42(10): 684-691．.
3. 　张惠茅, 王睿, 胡博奇. 多排螺旋CT对冠状动脉斑块的诊断价值[J]. 中国实验诊断学, 2010, 14(7): 1158-1159.
4. 　Scbroeder S, Kopp AF, Bnambaeb A, et al. Noninvasive detection and evaluation of athemscleratic coronary plaques with muhilice computed tomography[J]. J Am Coil Cardiol, 2001, 37(5): 1430-1435.
5. 　李玉林,唐建武.病理学[M]. 6版. 北京: 人民卫生出版社, 2003: 132-134.
6. 　李甘地, 来茂德．病理学(七年制)[M]. 北京: 人民卫生出版社, 2001: 159-161．.
7. 　Tanaka A, Shimada K, Sano T, et al. Multiple plaque ruptureand C-reactive protein in acute myocardial infarction[J]. J Am Coil Cardiol, 2005, 45(10): 1594-1599．.
8. 　Fujii K, Mintz GS, Kobayashi Y, et al. Vascular remodeling and plaque composition between focal and difuse coronary lesions assessed by in travascular ultrasound[J]. Am J Cardiol, 2004, 94(8): 1067-1070.
9. 　毛定飙, 滑炎卿, 王鸣鹏, 等. 心率及重建相位窗对多层螺旋CT冠状动脉造影图像质量的影响[J]. 中华放射学杂志, 2004, 38(5): 521-524．.
10. 　Kaski JC. Athelomatous plaque location and arterial remodelling[J]. Eur Heart J, 2003, 24(4): 291-293.
11. 　靳海斌, 王旭开, 杨成明, 等. 64层CT冠状动脉成像与冠状动脉造影的影像对比研究[J]. 重庆医学, 2008, 37(6): 597-599．.
12. 　黄贤胜, 曹振东, 李俊玫, 等. 64层螺旋CT对冠状动脉粥样硬化斑块的诊断价值[J]. 放射学实践, 2009, 24(5): 487-490．.
13. 　肖喜刚, 韩雪, 王雪红, 等. 多层螺旋CT冠状动脉成像在冠心病中的临床应用[J]. 中华放射学杂志, 2004, 38(9): 957-961．.

West China Medical Journal

Correlation between Coronary Plaque Composition and Degree of Stenosis by 128-slice Spiral Computed Tomography Coronary Angiography in Patients with Coronary Heart Disease

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