Analysis on MRI Misdiagnosis of Primary Gallbladder Carcinoma_West China Medical Journal

Authors：

 ZENGLi-chuan , YANGHan-feng , XUXiao-xue , LIYang , NIUXiang-ke , SUNFeng ,  DUYong

Department of Radiology, Affiliated Hospital of North Sichuan Medical College/Sichuan Key Laboratory of Medical Imaging, Nanchong, Sichuan 637000, P. R. China;

Corresponding author：

DUYong, Email: yongdu2005@163.com

Keywords：

Primary gallbladder carcinoma; Magnetic resonance imaging; Misdiagnosis

DOI：

10.7507/1002-0179.20140154

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Objective To analyze the MR findings of primary gallbladder carcinoma so as to improve the diagnostic accuracy. Methods A retrospective study was developed involving 15 primary gallbladder carcinoma patients identified by postoperative pathology between January 2010 and March 2013. Imaging findings were analyzed including lesions location, enhancement characteristics, the dilatation of bile ducts and gallstones. Results Among the 15 gallbladder carcinoma patients, 5 were misdiagnosed as neoplasms in the porta hepatis combined with dilation of intrahepatic bile ducts. Intra- and extrahepatic bile ducts dilated in 7 patients, which were misdiagnosed as tumors or inflammation. Two cases of gallbladder carcinoma with right lobe mass were misdiagnosed as gallbladder polyps. One patient was misdiagnosed as cholecystitis. The retrospective analysis revealed that the gallbladder wall thickened in 12 cases, with focal thickening in 9 and diffuse thickening in 3 cases. Enhanced scanning demonstrated that gallbladder wall enhanced in varying degrees, and 11 cases had delayed enhancement features. There were 8 patients with gallstones and 2 with gallbladder wall nodules. Conclusion Primary gallbladder carcinoma can easily cause bile duct dilatation, and manifests as focal or diffuse mural thickening, often accompanied by gallstones.

Citation： ZENGLi-chuan, YANGHan-feng, XUXiao-xue, LIYang, NIUXiang-ke, SUNFeng, DUYong. Analysis on MRI Misdiagnosis of Primary Gallbladder Carcinoma. West China Medical Journal, 2014, 29(3): 514-516. doi: 10.7507/1002-0179.20140154 Copy

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1. Bartlett DL. Gallbladder cancer[J]. Semin Surg Oncol, 2000, 19(2):145-155.
2. Eslick GD. Epidemiology of gallbladder cancer[J]. Gastroenterol Clin North Am, 2010, 39(2):307-330.
3. Biswas PK. Carcinoma gallbladder[J]. Mymensingh Med J, 2010, 19(3):477-481.
4. Boutros C, Gary M, Baldwin K, et al. Gallbladder cancer:past, present and an uncertain future[J]. Surg Oncol, 2012, 21(4):e183-e191.
5. Gourgiotis S, Kocher HM, Solaini L, et al. Gallbladder cancer[J]. Am J Surg, 2008, 196(2):252-264.
6. Catalano OA, Sahani DV, Kalva SP, et al. Mr imaging of the gallbladder:a pictorial essay[J]. Radiographics, 2008, 28(1):135-155.
7. Muratore A, Polastri R, Capussotti L. Radical surgery for gallbladder cancer:current options[J]. Eur J Surg Oncol, 2000, 26(5):438-443.
8. Ito M, Mishima Y, Sato T. An anatomical study of the lymphatic drainage of the gallbladder[J]. Surg Radiol Anat, 1991, 13(2):89-104.
9. Tsukada K, Kurosaki I, Uchida K, et al. Lymph node spread from carcinoma of the gallbladder[J]. Cancer, 1997, 80(4):661-667.
10. Levy AD, Murakata LA, Rohrmann CA. Gallbladder carcinoma:radiologic-pathologic correlation[J]. Radiographics, 2001, 21(2):295-314.
11. Kaza RK, Gulati M, Wig JD, et al. Evaluation of gall bladder carcinoma with dynamic magnetic resonance imaging and magnetic resonance cholangiopancreatography[J]. Australas Radiol, 2006, 50(3):212-217.
12. Shukla VK, Sharma D, Dixit VK. Diagnostic value of serum CA242, CA 19-9, CA 15-3 and CA 125 in patients with carcinoma of the gallbladder[J]. Trop Gastroenterol, 2007, 27(4):160-165.

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