Investigation and Analysis on the Nosocomial Infection in 1 621 Hospitalized Patients with Acute and Serious Schizophrenia_West China Medical Journal

Authors：

 LIShui-ying , ZHOUQian , ZHANGXiu-ying , WANGQiang ,  SHENWen-wu

Mental Health Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

SHENWen-wu, Email: wenwu_shen@163.com

Keywords：

Nosocomial infection; Schizophrenia; Risk factors

DOI：

10.7507/1002-0179.20140624

Video：

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Objective To investigate the incidence of nosocomial infection in acute and serious schizophrenic inpatients and its risk factors. Methods Between January 1st and December 31st, 2012, we investigated 1 621 schizophrenic patients on the status of nosocomial infections according to the hospital standard of nosocomial infection diagnosis. They were divided into infected group and uninfected group according to the survey results. The risk factors were analyzed by logistic regression method. Results Twenty-nine infected patients were found among the 1 621 patients, and the incidence rate was 1.79%. Among the nosocomial infections, the most common one was respiratory infection (79.31%), followed by gastrointestinal infection and urinary infection (6.90%). There were significant differences between the two groups of patients in age, hospital stay, positive and negative syndrome scale (PASS), combined somatopathy, the time of protective constraint, modified electraconvulsive therapy (MECT), using two or more antipsychotics drugs, using antibiotics and side effects of drugs (P<0.05). However, there were no statistical differences in gender, age classes, the course of disease, frequency of hospitalization and seasonal incidence of hospital infection (P>0.05). The results of multivariate analysis showed that hospital stay, positive symptom score, negative symptom score, the time of protective constraint, MECT, using two or more antipsychotics drugs and side effects of drugs were the main risk factors for nosocomial infection of inpatients with psychopathy (P<0.05). Conclusion Based on the different traits and treatments of acute and serious schizophrenia, a screening table of infections should be set. For the high risk group of nosocomial infection, effective measures should be taken to prevent and control the nosocomial infection of patients with schizophrenia.

Citation： LIShui-ying, ZHOUQian, ZHANGXiu-ying, WANGQiang, SHENWen-wu. Investigation and Analysis on the Nosocomial Infection in 1 621 Hospitalized Patients with Acute and Serious Schizophrenia. West China Medical Journal, 2014, 29(11): 2073-2076. doi: 10.7507/1002-0179.20140624 Copy

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1. 傅小芳, 张继东, 黄佳荃, 等. 医院感染引起医疗损害责任认定及对策[J]. 中国医院, 2011, 15(3):58-59.
2. 张淑平, 谭慕杨. 风险管理在医院感染管理中的应用与效果分析[J]. 华西医学, 2012, 27(1):129-131.
3. Klevens RM, Edwards JR, Richards CL, et al. Estimating health care-associated infections and deaths in U.S. hospitals, 2002[J]. Public Health Rep, 2007, 122(2):160-166.
4. 潘利, 杨玲花. 精神分裂症医院感染的特点及控制方法[J]. 中国民康医学, 2010, 22(23):3062-3064.
5. 于云彩. 精神病专科医院医院感染横断面调查结果的变化趋势研究[J]. 现代预防医学, 2010, 37(6):1060-1061.
6. 程敏锋, 温盛霖, 魏钦令. 综合医院精神科住院患者医院获得性肺炎的临床分析[J]. 中华医院感染学杂志, 2011, 21(15):3162-3163.
7. 李运莲. 精神科住院患者医院感染现状分析[J]. 中国民康医学, 2010, 22(17):2210-2212.
8. 陈正平, 陈晓华, 王顺铨. 保护性约束精神病患者医院感染研究[J]. 中华医院感染学杂志, 2007, 17(12):1523-1524.
9. 王顺铨, 陈晓华, 金正. 无抽搐电休克治疗精神病患者医院感染研究[J]. 中华医院感染学杂志, 2010, 20(2):215-216.
10. 周东升, 徐银儿, 宋平, 等. 住院精神病患者感染性腹泻影响因素病例对照研究[J]. 中华医院感染学杂志, 2012, 22(13):2833-2835.
11. 中华人民共和国卫生部. 医院感染诊断标准(试行)[EB/OL]. (2011-11-07)[2013-09-09]. http://www.moh.gov.cn/yzygj/s3593/200804/e19e4448378643a09913ccf2a055c79d.shtml.
12. 世界卫生组织. ICD-10精神与行为障碍分类[M]. 范肖冬, 汪向东, 于欣, 等, 译. 北京:人民卫生出版社, 1993:7-225.
13. 邵磊, 钱敏才,徐美英. 浙江省精神病专科医院住院患者疾病谱的分析[J]. 解放军护理杂志, 2011, 28(11A):22-23.
14. 庞丽, 娄峥. 2010~2012年上海精神专科医院病原菌分布和耐药性分析[J]. 现代检验医学杂志, 2013, 28(5):132-134.
15. 张德伦, 沈宁平, 姚鹏. 11048例精神科住院患者抗菌药物使用情况调查分析[J]. 中国执业药师, 2013, 10(9):6-8.

West China Medical Journal

Investigation and Analysis on the Nosocomial Infection in 1 621 Hospitalized Patients with Acute and Serious Schizophrenia

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