The Characteristics and Diagnostic Values of MRI for Multiple Sclerosis_West China Medical Journal

Authors：

 HULi-ping

Department of Medical Imaging, Chengdu Tianfu New District People's Hospital, Chengdu, Sichuan 610213, P. R. China;

Corresponding author：

Keywords：

Multiple sclerosis; Imaging characteristics; Magnetic resonance imaging; Diagnostic values

DOI：

10.7507/1002-0179.20150315

Video：

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Objective To investigate the morphology of brain regions undergoing multiple sclerosis (MS) MRI, and furthermore, to investigate possible diagnostic values of MRI for MS. Methods MRI images of 42 MS patients (34 females and 8 males, aged between 35 and 81 years old, averaging at 58) who visited the hospital during the time from December 2007 to December 2013 were collected and analyzed. Routine T1, T2 and fluid attenuated inversion recovery (FLAIR) scans were performed on all the 42 patients. Sagittal T1, T2 and FLAIR scans were performed when necessary. Contrast-enhanced MRI was performed on 9 of the 42 patients. The abnormal findings from MRI scans of all the 42 patients were analyzed. The analysis was further concluded to yield general characteristics of MS patients under MRI. Results A total of 286 lesions were identified in 42 patients. Ninety (31.6%) of the 286 lesions (seen in 35 patients) were found to locate around lateral ventricles; 67 (23.4%) at centrum semiovale (seen in 29 patients); 59 (20.6%) in deep white matter (seen in 28 patients); 46 (16.1%) around corpus callosum (seen in 30 patients); 21 (7.3%) in brain stem, basal ganglia and cerebellar hemispheres (seen in 9 patients); and 3 (1.0%) at cervical spinal cord. In routine MRI images, the lesions showed up as low T1 signal, high T2 signal and high FLAIR signal with the shape of ovoid or round. No mass effect was observed in lesions. In the contrast-enhanced MRI images, the 25 observed lesions showed mild enhancements with the shape of ring, semi-ring and arc. Conclusion Certain characteristic features can be observed in MS MRI images. MRI is an effective diagnostic method for multiple sclerosis diagnosis.

Citation： HULi-ping. The Characteristics and Diagnostic Values of MRI for Multiple Sclerosis. West China Medical Journal, 2015, 30(6): 1101-1104. doi: 10.7507/1002-0179.20150315 Copy

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1. 卢德宏, 汤国才. 多发性硬化的临床病理学[J]. 实用儿科临床杂志, 2005, 20(4):293-296.
2. Dineen RA, Vilisaar J, Hlinka J, et al. Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis[J]. Brain, 2009, 132(Pt 1):239-249.
3. Thornton AE, Raz N, Tucke KA. Memory in multiple sclerosis:contextual encoding deficits[J]. J Int Neuropsychol Soc, 2002, 8(3):395-409.
4. Calabrese M, Agosta F, Rinaldi F, et al. Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis[J]. Arch Neurol, 2009, 66(9):1144-1150.
5. 李世平, 周毅, 卢兰香, 等. 多发性硬化认知障碍分析[J]. 河北医药, 2014, 36(11):1656-1658.
6. Mcdonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis:guidelines from the International Panel on the diagnosis of multiple sclerosis[J]. Ann Neurol, 2001, 50(1):121-127.
7. 刘沛武, 吴文泽, 刘四斌. 多发性硬化76例MRI诊断分析[J]. 中国误诊学杂志, 2011, 11(1):179.
8. 赵新湘, 王波, 戴敏方, 等. 多发性硬化MRI表现及其诊断价值[J]. 医学影像学杂志, 2004, 14(8):620-623.
9. 张丽, 汤春贵, 郝淑彬. 颅脑多发性硬化MRI表现[J]. 中国医药导报, 2011, 8(22):96-97, 104.
10. He J, Grossman RI, Ge Y, et al. Enhancing patterns in multiple sclerosis:evolution and persistence[J]. AJNR Am J Neuroradiol, 2001, 22(4):664-669.
11. Balashov KE, Aung LL, Dhib-Jalbut S, et al. Acute multiple sclerosis lesion:conversion of restricted diffusion due to vasogenic edema[J]. J Neuroimaging, 2011, 21(2):202-204.
12. 冯逢. 多发性硬化的常见MRI征象分析[J]. 磁共振成像, 2011, 2(4):309-313.
13. 宋峰, 宦怡. MRI在多发性硬化病理机制研究中的应用[J]. 放射学实践, 2009, 24(12):1383-1385.

West China Medical Journal

The Characteristics and Diagnostic Values of MRI for Multiple Sclerosis

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