Treatment experiences of 516 cases of diabetic foot treated with tibial transverse transport_Chinese Journal of Reparative and Reconstructive Surgery

Authors：

HUA Qikai ¹ , QIN Sihe ² , KUANG Xiaocong ³ , CHEN Yan ¹ , QU Long ⁴ ,  ZHAO Jinmin ^1,5

1. Department of Bone and Joint Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning Guangxi, 530021, P.R.China;
2. Department of Orthopedics, Rehabilitation Hospital of the National Research Center for Rehabilitation Technical Aids, Beijing, 100176, P.R.China;
3. Department of Physiopathology, Preclinical School of Guangxi Medical University, Nanning Guangxi, 530021, P.R.China;
4. Department of Orthopedic Surgery, Aerospace 731 Hospital, Beijing, 100000, P.R.China;
5. Center of Regenerative Medicine, Guangxi Medical University, Nanning Guangxi, 530021, P.R.China;

Corresponding author：

ZHAO Jinmin, Email: zhaojinmin@126.com

Keywords：

Tibial transverse transport; diabetic foot; treatment experience

DOI：

10.7507/1002-1892.202003099

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Tibial transverse transport (TTT) was firstly applied to treat thromboangiitis obliterans successfully by Professor QU Long in China in 2000. Based on this, the team of Professor HUA Qikai in the First Affiliated Hospital of Guangxi Medical University applied this technique to treat diabetic foot since 2013, and until now, more than 500 patients underwent this treatment with excellent effectiveness including a salvage rate as high as 96.1%. Our team also improved this technique in many aspects, and developed a TTT-based classification system and treatment for diabetic foot. We also explored the underlying mechanism of TTT treatment using imaging, histology, and other basic research methods. To further promote the application of this technique in clinic, we reported the findings from our cases and reviewed our previous findings in this study.

Citation： HUA Qikai, QIN Sihe, KUANG Xiaocong, CHEN Yan, QU Long, ZHAO Jinmin. Treatment experiences of 516 cases of diabetic foot treated with tibial transverse transport. Chinese Journal of Reparative and Reconstructive Surgery, 2020, 34(8): 959-963. doi: 10.7507/1002-1892.202003099 Copy

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2.	秦泗河. Ilizarov 技术概述. 中华骨科杂志, 2006, 26(9): 642-645.
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4.	冼呈, 赵劲民, 苏伟, 等. 胫骨横向骨搬移微循环再生技术治疗糖尿病足的临床疗效观察. 广西医科大学学报, 2015, 32(4): 605-607.
5.	花奇凯, 秦泗河, 赵良军, 等. Ilizarov 技术胫骨横向骨搬移术治疗糖尿病足. 中国矫形外科杂志, 2017, 25(4): 303-307.
6.	Chen Y, Kuang XC, Zhou J, et al. Proximal tibial cortex transverse distraction facilitating healing and limb salvage in severe and recalcitrant diabetic foot ulcers. Clin Orthop Relat Res, 2020, 478(4): 836-851.
7.	Zeng Z, Dong Y, Hua QK, et al. Computed tomography perfusion study evaluating the curative effect of tibial transverse transport in patients with severe diabetic foot. Journal of Orthopaedic Translation, 2019, 19: 133-142.
8.	何立环, 陈炎, 邝晓聪, 等. 重度糖尿病足胫骨横向骨搬移术治疗后创面愈合规律分析. 中医正骨, 2019, 31(10): 70-73.
9.	连浩宇, 花奇凯, 陈炎, 等. 重度糖尿病足胫骨横向骨搬移术治疗后创面愈合方式及机制研究. 中医正骨, 2019, 31(12): 15-19.
10.	镇普祥, 陈炎, 高伟, 等. 应用 Ilizarov 技术胫骨横向骨搬移术治疗合并全身性炎症反应综合征的重度糖尿病足. 中国修复重建外科杂志, 2018, 31(10): 1261-1266.
11.	高伟, 林震迅, 镇普祥, 等. 胫骨横向骨搬移后巨噬细胞促进重度糖尿病足创面的愈合. 中国组织工程研究杂志, 2018, 22(36): 5811-5815.

1. Ilizarov GA. The tension-stress effect on the genesis and growth of tissues: Part Ⅱ. The influence of the rate and frequency of distraction. Clin Orthop Relat Res, 1989, (239): 263-285.
2. 秦泗河. Ilizarov 技术概述. 中华骨科杂志, 2006, 26(9): 642-645.
3. 曲龙, 王爱林, 汤福刚. 胫骨横向搬移血管再生术治疗血栓闭塞性脉管炎. 中华医学杂志, 2001, 81(10): 622-624.
4. 冼呈, 赵劲民, 苏伟, 等. 胫骨横向骨搬移微循环再生技术治疗糖尿病足的临床疗效观察. 广西医科大学学报, 2015, 32(4): 605-607.
5. 花奇凯, 秦泗河, 赵良军, 等. Ilizarov 技术胫骨横向骨搬移术治疗糖尿病足. 中国矫形外科杂志, 2017, 25(4): 303-307.
6. Chen Y, Kuang XC, Zhou J, et al. Proximal tibial cortex transverse distraction facilitating healing and limb salvage in severe and recalcitrant diabetic foot ulcers. Clin Orthop Relat Res, 2020, 478(4): 836-851.
7. Zeng Z, Dong Y, Hua QK, et al. Computed tomography perfusion study evaluating the curative effect of tibial transverse transport in patients with severe diabetic foot. Journal of Orthopaedic Translation, 2019, 19: 133-142.
8. 何立环, 陈炎, 邝晓聪, 等. 重度糖尿病足胫骨横向骨搬移术治疗后创面愈合规律分析. 中医正骨, 2019, 31(10): 70-73.
9. 连浩宇, 花奇凯, 陈炎, 等. 重度糖尿病足胫骨横向骨搬移术治疗后创面愈合方式及机制研究. 中医正骨, 2019, 31(12): 15-19.
10. 镇普祥, 陈炎, 高伟, 等. 应用 Ilizarov 技术胫骨横向骨搬移术治疗合并全身性炎症反应综合征的重度糖尿病足. 中国修复重建外科杂志, 2018, 31(10): 1261-1266.
11. 高伟, 林震迅, 镇普祥, 等. 胫骨横向骨搬移后巨噬细胞促进重度糖尿病足创面的愈合. 中国组织工程研究杂志, 2018, 22(36): 5811-5815.

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Treatment experiences of 516 cases of diabetic foot treated with tibial transverse transport

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