• 1. Department of Thoracic Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, P. R. China;
  • 2. Lung Transplant Center of Wuxi People’s Hospital, Affiliated Hospital of Nanjing Medical University, Wuxi, 214043, Jiangsu, P. R. China;
  • 3. Department of Lung Transplantation, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310052, P. R. China;
CHEN Jingyu, Email: chenjy@wuxiph.com
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Lung cancer is the most prevalent malignant tumor worldwide. For lung cancer patients with multiple intrapulmonary metastases or impaired lung function, complete tumor resection is challenging, and the prognosis is poor. Lung transplantation demonstrates potential therapeutic value in achieving complete tumor resection, improving lung function, and enhancing quality of life. Advances in tumor detection technologies such as positron emission tomography-computed tomography and circulating tumor DNA, along with the development of comprehensive treatment strategies for lung cancer, provide powerful tools for accurately predicting tumor recurrence and treatment outcomes following lung transplantation. The feasibility of lung transplantation as a treatment for lung cancer is receiving increasing attention. This article reviews the history and clinical management of lung transplantation for lung cancer.

Citation: TAN Jinghong, CHENG Chao, CHEN Jingyu. Lung transplantation for lung cancer: History, current status, and future. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2025, 32(6): 760-765. doi: 10.7507/1007-4848.202411008 Copy

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