Bibliometric and Research Hotspots Analysis of Pancreatic Neoplasms and Molecular Imaging in Recent Five Years_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 WUMing-peng ¹ , QIANRong ¹ , CHENJie ¹ , ZHANGXiao ² , HUANGZi-xing ¹ ,  SONGBin ¹

1. Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China;
2. Department of CT/MRI, Leshan People's Hospital, Leshan 614000, Sichuan Province, China;

Corresponding author：

SONGBin, Email: cjr.songbin@vip.163.com

Keywords：

Pancreatic neoplasms; Molecular imaging; Research hotspot; Bibliometric analysis

DOI：

10.7507/1007-9424.20140314

Video：

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Objective To investigate researches on pancreatic neoplasms and molecular imaging in recent five years and provide reference information for the majority of professionals in deep research. Methods Bibliographies from research literature of pancreatic neoplasms and molecular imaging in recent five years in PubMed database were downloaded. The publication years, journals, countries of publication, the first authors and the frequency of MJMEs were counted by Bicomb 2.0 software. The affiliations were analyzed artificially. MJMEs appeared no less than two times were intercepted as high frequency ones and the high frequency MJMEs co-occurrence matrix were formed. SPSS 22.0 statistical software were applied for clustering analysis with matrix, then to get the topic hotspots. Results A total of 28 literatures were screened out. The data of research trend, journals, research degree of countries were acquired. The number of high frequency MJMEs were 20 and among which 5 research hotspots were clustered. Conclusions Researches on pancreatic neoplasms and molecular imaging are mainly in terms of therapy and genetics, diagnosis and metabolism, radionuclide imaging, pharmacology and pathology.

Citation： WUMing-peng, QIANRong, CHENJie, ZHANGXiao, HUANGZi-xing, SONGBin. Bibliometric and Research Hotspots Analysis of Pancreatic Neoplasms and Molecular Imaging in Recent Five Years. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2014, 21(10): 1305-1310. doi: 10.7507/1007-9424.20140314 Copy

1.	崔雷, 刘伟, 闫雷, 等.文献数据库中书目信息共现挖掘系统的开发[J].现代图书情报技术, 2008, 8:70-75.
2.	张晗, 崔雷.运用共词聚类分析法研究生物信息学的学科热点[J].医学情报工作, 2004, 25(5):327-330.
3.	Haddad D, Zanzonico PB, Carlin S, et al. A vaccinia virus encoding the human sodium iodide symporter facilitates long-term image monitoring of virotherapy and targeted radiotherapy of pancreatic cancer[J]. J Nucl Med, 2012, 53(12):1933-1942.
4.	Haddad D, Chen CH, Carlin S, et al. Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter[J]. PLoS One, 2012, 7(8):e41647.
5.	Nimmagadda S, Pullambhatla M, Lisok A, et al. Imaging Axl expression in pancreatic and prostate cancer xenografts[J]. Biochem Biophys Res Commun, 2014, 443(2):635-640.
6.	Foygel K, Wang H, Machtaler S, et al. Detection of pancreatic ductal adenocarcinoma in mice by ultrasound imaging of thymocyte differentiation antigen1[J]. Gastroenterology, 2013, 145(4):885-894.
7.	Hackel BJ, Kimura RH, Miao Z, et al. 18F-fluorobenzoate-labeled cystine knot peptides for PET imaging of integrinαvβ6[J]. J Nucl Med, 2013, 54(7):1101-1105.
8.	Tong M, Xiong F, Shi Y, et al. In vitro study of SPIO-labeled human pancreatic cancer cell line BxPC-3[J]. Contrast Media Mol Imaging, 2013, 8(2):101-107.
9.	Suetsugu A, Katz M, Fleming J, et al. Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice[J]. Anticancer Res, 2012, 32(8):3063-3067.
10.	Lindholm DP, Oberg K. Biomarkers and molecular imaging in gastroenteropancreatic neuroendocrine tumors[J]. Horm Metab Res, 2011, 43(12):832-837.
11.	Eser S, Messer M, Eser P, et al. In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging[J]. Proc Natl Acad Sci U S A, 2011, 108(24):9945-9950.
12.	Kaemmerer D, Peter L, Lupp A, et al. Molecular imaging with ⁶⁸Ga-SSTR PET/CT and correlation to immunohistochemistry of somatostatin receptors in neuroendocrine tumours[J]. Eur J Nucl Med Mol Imaging, 2011, 38(9):1659-1668.
13.	Amirkhanov NV, Zhang K, Aruva MR, et al. Imaging human pancreatic cancer xenografts by targeting mutant KRAS2 mRNA with[(111)In] DOTA(n)-poly (diamidopropanoyl) (m)-KRAS2 PNA-D(Cys-Ser-Lys-Cys) nanoparticles[J]. Bioconjug Chem, 2010, 21(4):731-740.
14.	de Herder WW. GEP-NETS update:functional localisation and scintigraphy in neuroendocrine tumours of the gastrointestinal tract and pancreas (GEP-NETs)[J]. Eur J Endocrinol, 2014, 170(5):R173-R183.
15.	Miederer M, Weber MM, Fottner C. Molecular imaging of gastroenteropancreatic neuroendocrine tumors[J]. Gastroenterol Clin North Am, 2010, 39(4):923-935.
16.	Brullé L, Vandamme M, Riès D, et al. Effects of a non thermal plasma treatment alone or in combination with gemcitabine in a MIA PaCa2-luc orthotopic pancreatic carcinoma model[J]. PLoS One, 2012, 7(12):e52653.
17.	Poeschinger T, Renner A, Weber T, et al. Bioluminescence imaging correlates with tumor serum marker, organ weights, histology, and human DNA levels during treatment of orthotopic tumor xenografts with antibodies[J]. Mol Imaging Biol, 2013, 15(1):28-39.
18.	Drifka CR, Eliceiri KW, Weber SM, et al. A bioengineered heterotypic stroma-cancer microenvironment model to study pancreatic ductal adenocarcinoma[J]. Lab Chip, 2013, 13(19):3965-3975.
19.	Wu CY, Pu Y, Liu G, et al. MR imaging of human pancreatic cancer xenograft labeled with superparamagnetic iron oxide in nude mice[J]. Contrast Media Mol Imaging, 2012, 7(1):51-58.
20.	Earley S, Vinegoni C, Dunham J, et al. In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single-cell resolution[J]. Cancer Res, 2012, 72(12):2949-2956.

1. 崔雷, 刘伟, 闫雷, 等.文献数据库中书目信息共现挖掘系统的开发[J].现代图书情报技术, 2008, 8:70-75.
2. 张晗, 崔雷.运用共词聚类分析法研究生物信息学的学科热点[J].医学情报工作, 2004, 25(5):327-330.
3. Haddad D, Zanzonico PB, Carlin S, et al. A vaccinia virus encoding the human sodium iodide symporter facilitates long-term image monitoring of virotherapy and targeted radiotherapy of pancreatic cancer[J]. J Nucl Med, 2012, 53(12):1933-1942.
4. Haddad D, Chen CH, Carlin S, et al. Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter[J]. PLoS One, 2012, 7(8):e41647.
5. Nimmagadda S, Pullambhatla M, Lisok A, et al. Imaging Axl expression in pancreatic and prostate cancer xenografts[J]. Biochem Biophys Res Commun, 2014, 443(2):635-640.
6. Foygel K, Wang H, Machtaler S, et al. Detection of pancreatic ductal adenocarcinoma in mice by ultrasound imaging of thymocyte differentiation antigen1[J]. Gastroenterology, 2013, 145(4):885-894.
7. Hackel BJ, Kimura RH, Miao Z, et al. 18F-fluorobenzoate-labeled cystine knot peptides for PET imaging of integrinαvβ6[J]. J Nucl Med, 2013, 54(7):1101-1105.
8. Tong M, Xiong F, Shi Y, et al. In vitro study of SPIO-labeled human pancreatic cancer cell line BxPC-3[J]. Contrast Media Mol Imaging, 2013, 8(2):101-107.
9. Suetsugu A, Katz M, Fleming J, et al. Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice[J]. Anticancer Res, 2012, 32(8):3063-3067.
10. Lindholm DP, Oberg K. Biomarkers and molecular imaging in gastroenteropancreatic neuroendocrine tumors[J]. Horm Metab Res, 2011, 43(12):832-837.
11. Eser S, Messer M, Eser P, et al. In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging[J]. Proc Natl Acad Sci U S A, 2011, 108(24):9945-9950.
12. Kaemmerer D, Peter L, Lupp A, et al. Molecular imaging with ⁶⁸Ga-SSTR PET/CT and correlation to immunohistochemistry of somatostatin receptors in neuroendocrine tumours[J]. Eur J Nucl Med Mol Imaging, 2011, 38(9):1659-1668.
13. Amirkhanov NV, Zhang K, Aruva MR, et al. Imaging human pancreatic cancer xenografts by targeting mutant KRAS2 mRNA with[(111)In] DOTA(n)-poly (diamidopropanoyl) (m)-KRAS2 PNA-D(Cys-Ser-Lys-Cys) nanoparticles[J]. Bioconjug Chem, 2010, 21(4):731-740.
14. de Herder WW. GEP-NETS update:functional localisation and scintigraphy in neuroendocrine tumours of the gastrointestinal tract and pancreas (GEP-NETs)[J]. Eur J Endocrinol, 2014, 170(5):R173-R183.
15. Miederer M, Weber MM, Fottner C. Molecular imaging of gastroenteropancreatic neuroendocrine tumors[J]. Gastroenterol Clin North Am, 2010, 39(4):923-935.
16. Brullé L, Vandamme M, Riès D, et al. Effects of a non thermal plasma treatment alone or in combination with gemcitabine in a MIA PaCa2-luc orthotopic pancreatic carcinoma model[J]. PLoS One, 2012, 7(12):e52653.
17. Poeschinger T, Renner A, Weber T, et al. Bioluminescence imaging correlates with tumor serum marker, organ weights, histology, and human DNA levels during treatment of orthotopic tumor xenografts with antibodies[J]. Mol Imaging Biol, 2013, 15(1):28-39.
18. Drifka CR, Eliceiri KW, Weber SM, et al. A bioengineered heterotypic stroma-cancer microenvironment model to study pancreatic ductal adenocarcinoma[J]. Lab Chip, 2013, 13(19):3965-3975.
19. Wu CY, Pu Y, Liu G, et al. MR imaging of human pancreatic cancer xenograft labeled with superparamagnetic iron oxide in nude mice[J]. Contrast Media Mol Imaging, 2012, 7(1):51-58.
20. Earley S, Vinegoni C, Dunham J, et al. In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single-cell resolution[J]. Cancer Res, 2012, 72(12):2949-2956.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Bibliometric and Research Hotspots Analysis of Pancreatic Neoplasms and Molecular Imaging in Recent Five Years

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