Imaging manifestations of focal parenchymal liver injury induced by chemotherapy in a case of gastric cancer_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

XING Cuicui ^1,2 , WU Jian ¹ , ZHANG Meng ¹ ,  LIU Xijiao ^1,2,3 , CHEN Weixia ² , SONG Bin ^1,2,3

1. Department of Radiology, Sanya People’s Hospital/West China Sanya Hospital, Sichuan University, Sanya, Hainan 572000, P. R. China;
2. Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
3. Key Laboratory of Functional and Molecular Imaging, Sichuan Province, Chengdu 610041, P. R. China;

Corresponding author：

LIU Xijiao, Email: bless_jiao@163.com

Keywords：

chemotherapy-induced liver injury; focal liver injury; imaging; differential diagnosis; metastatic tumor

DOI：

10.7507/1007-9424.202412144

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Tumor chemotherapy is a treatment method that employs chemotherapeutic drugs to eradicate cancer cells. These drugs are cytotoxic, meaning they can affect both tumor cells and normal cells. In recent years, there has been a gradual increase in chemotherapy-induced liver injury. Chemotherapy-induced parenchymal liver injury often manifests as diffuse lesions, although focal lesions can occasionally be observed. There is a diversity in the pathogenesis and pathological changes of chemotherapy-induced focal liver disease. Radiologically, there is often challenging in differentiating chemotherapy-induced focal liver disease from hepatic metastases. Therefore, early and accurate diagnosis of this condition poses a certain challenge in clinical practice. This article presents the radiological findings of a case of chemotherapy-induced focal liver disease induced by chemotherapy for gastric cancer, and summarizes the radiological features and differential diagnostic points of chemotherapy-induced focal liver disease, aiming to enhance the understanding of this type of lesion among radiologists and clinicians and reduce related missed diagnoses and misdiagnoses.

Citation： XING Cuicui, WU Jian, ZHANG Meng, LIU Xijiao, CHEN Weixia, SONG Bin. Imaging manifestations of focal parenchymal liver injury induced by chemotherapy in a case of gastric cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2025, 32(5): 564-567. doi: 10.7507/1007-9424.202412144 Copy

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CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Imaging manifestations of focal parenchymal liver injury induced by chemotherapy in a case of gastric cancer

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