Citation： 何权瀛. 支气管哮喘临床诊治：现状与未来. Chinese Journal of Respiratory and Critical Care Medicine, 2019, 18(1): 1-4. doi: 10.7507/1671-6205.201805045 Copy
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| 1. | 中华医学会呼吸系病学会哮喘学组. 支气管哮喘的定义、诊断、严重度分级及疗效判断标准 (修正方案). 中华结核和呼吸杂志, 1993, 16(1): 9-10. |
| 2. | 中华医学会呼吸病学分会. 支气管哮喘防治指南 (支气管哮喘的定义、诊断、治疗、疗效判断标准及教育和管理方案). 中华结核和呼吸杂志, 1997, 20(5): 261-267. |
| 3. | 中华医学会呼吸病学分会. 支气管哮喘防治指南 (支气管哮喘的定义、诊断、治疗、及教育和管理方案). 中华结核和呼吸杂志, 2003, 26(23): 132-138. |
| 4. | 中华医学会呼吸病学分会哮喘学组. 支气管哮喘防治指南 (支气管哮喘的定义、诊断、治疗及管理方案). 中华结核和呼吸杂志, 2008, 31(3): 177-185. |
| 5. | 中华医学会呼吸病分会哮喘学组. 支气管哮喘防治指南 (2016 年版). 中华结核和呼吸杂志, 2016, 39(9): 675-697. |
| 6. | 中华医学会呼吸病分会哮喘学组. 支气管哮喘控制的中国专家共识. 中华内科杂志, 2013, 52(5): 440-443. |
| 7. | 中华医学会呼吸病分会哮喘学组, 中国哮喘联盟. 支气管哮喘急性发作评估及处理. 中国专家共识. 中华内科杂志, , 2018, 57(1): 4-14. |
| 8. | 中华医学会呼吸病分会哮喘学组. 重症哮喘诊断与处理中国专家共识. 中华结核和呼吸杂志, 2017, 40(11): 813-829. |
| 9. | 中华医学会呼吸病分会哮喘学组. 难治性哮喘诊断与处理专家共识. 中华结核和呼吸杂志, 2010, 33(7): 572-577. |
| 10. | 中华医学会呼吸病分会哮喘学组. 支气管哮喘患者自我管理中国专家共识. 中华结核和呼吸杂志, 2018, 41(3): 171-178. |
| 11. | 苏楠, 林江涛, 刘国梁, 等. 我国 8 省市支气管哮喘患者控制水平的流行病学调查. 中华内科杂志, 2014, 53(8): 601-606. |
| 12. | 林江涛, 王文巧, 周新, 等. 我国 30 个省市城区门诊支气管哮喘患者控制水平的调查结果. 中华结核和呼吸杂志, 2017, 40(7): 494-498. |
| 13. | 林江涛, 王文巧, 周新, 等. 我国十城市支气管哮喘控制和疾病管理及患者认知水平的变化. 中华结核和呼吸杂志, 2018, 41(3): 191-195. |
| 14. | Katz LE, Gleich GJ, Hartley BF, et al. Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma. Ann Am Throac Soc, 2014, 11(4): 531-536. |
| 15. | Chung KF, Wenzel SE, Brozek JL, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J, 2014, 43(2): 343-373. |
| 16. | 陈荣昌. 呼吸与危重症医学 2016-2017. 北京: 人民卫生出版社, 2017, 123-126. |
| 17. | Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma (GINA) 2017. |
| 18. | Fanta CH. Asthma. N Engl J Med, 2009, 360(10): 1002-1014. |
| 19. | Bareman ED, Boushey HA, Bousquet J, et al. Can guideline-defined asthma control be achieved? The gaining optimal asthma control study. Am J Respir Crit Care Med, 2004, 170(8): 836-844. |
| 20. | Masoli M, Fabian D, Holt S, et al. The global burden of asthma: executive summary of the GINA Dissemination Committee Report. Allergy, 2004, 59(5): 469-478. |
| 21. | Roche WR, Beasley R, Williams JH, et al. Subepithelial fibrosis in the bronchi of asthmatics. Lancet, 1989, 1: 520-524. |
| 22. | Aikawa T, Shimura S, Sasaki H, et al. Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. Chest, 1992, 101: 916-921. |
| 23. | Tanaka H, Yamada G, Sakai T, et al. Increased airway vascularity in newly diagnosed asthma using a high-magnification bronchovideoscope. Am J Respir Crit Care Med, 2003, 168(12): 1495-1499. |
| 24. | Holgate ST, Wilson JR, Howarth PH. New insights into airway inflammation by endobronchial biopsy. Am Rev Respir Dis, 1992, 145(Suppl): S2-S6. |
| 25. | Redington AE, Madden J, Frew AJ, et al. Transforming growth factor-β1 in asthma: measurement in bronchoalveolar lavage fluid. Am J Respir Crit Care Med, 1997, 156(2 Pt 1): 642-647. |
| 26. | Minshall EM, Leung DY, Martin RJ, et al. Eosinophil-associated TGF-βl mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol, 1997, 17(3): 326-333. |
| 27. | Childhood Asthma Management Program Research Group, Szefler S, Weiss S, et al. Long-term effects of budesonide or nedocromil in children with asthma. N Engl J Med, 2000, 343: 1054-1063. |
| 28. | Holgate ST. The airway epithelium is central to the pathogenesis of asthma. Allergol Int, 2008, 57(1): 1-10. |
| 29. | Holgate ST, Davies DE, Lackie PM, et al. Epithelial-mesenchymal interactions in the pathogenesis of asthma. J. Allergy Clin Immunol, 2000, 105: 193-204. |
| 30. | Martinez FD, Wright AL, Taussig LM, et al. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med, 1995, 332(3): 133-138. |
| 31. | Hafkamp-de Groen E, Lingsma HF, Caudri D, et al. Predicting asthma in preschool children with asthma-like symptoms: validating and updating the PIAMA risk score. J Allergy Clin Immunol, 2013, 132(6): 1303-1310. |
| 32. | Amin P, Levin L, Epstein T, et al. Optimum predictors of childhood asthma: persistent wheeze or the asthma predictive index?. J Allergy Clin Immunol Pract, 2014, 2(6): 709-715. |
| 33. | Rodriguez-Martinez CE, Sossa-Briceno MP, Castro-Rodriguez JA. Factors predicting persistence of early wheezing through childhood and adolescence: a systematic review of the literature. J Astham Allergy, 2017, 10: 83-98. |
| 34. | Caudri D, Wijga A, A Schipper CM, et al. Predicting the long-term prognosis of children with symptoms suggestive of asthma at preschool age. J Allergy Clin Immunol, 2009, 124(5): 903-910. |
| 35. | Rubner FJ, Jackson DJ, Evans MD, et al. Early life rhinovirus wheezing, allergic sensitization, and asthma risk at adolescence. J Allergy Clin Immunol, 2017, 139(2): 501-507. |
| 36. | Csonka P, Kaila M, Laippala P, et al. Wheezing in early life and asthma at school age: predictors of symptom persistence. Pediatr Allergy Immunol, 2000, 11(4): 225-229. |
| 37. | Stiemsma LT, Renolds LA, Turvey SE, et al. The hygiene hypothesis: current perspectives and future therapies. Immunotargets Ther, 2015, 4: 143-157. |
| 38. | Just J, Belfar S, Wanin S, et al. Impact of innate and environmental factors on wheezing persistence during childhood. J Asthma, 2010, 47(4): 412-416. |
| 39. | Alfvén T, Braun-Fahrländer C, Brunekdreef B, et al. Allergic diseases and atopic sensitization in children related to farming and anthroposophic lifestyle--the PARSIFAL study. Allergy, 2006, 61(4): 414-421. |
| 40. | von Mutius E. The microbial environment and its influence on asthma prevention in early life. J Allergy Clin Immunol, 2016, 137(3): 680. |
| 41. | Ege MJ, Mayer M, Normand AC, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med, 2011, 364(8): 701-709. |
| 42. | Shreiner A, Huffnagle GB, Noverr MC. The " Microflora Hypothesis” of allergic disease. Adv Exp Med Biol, 2008, 635: 113-134. |
| 43. | Chung KF. Airway microbial dysbiosis in asthmatic patients: a target for prevention and treatment?. J Allergy Clin Immunol, 2017, 139(4): 1071-1081. |
| 44. | Abrahamsson TR, Jakobsson HE, Andersson AF, et al. Low gut microbiota diversity in early infancy precedes asthma at school age. Clin Exp Allergy, 2014, 44(6): 842-850. |
| 45. | Arrieta MC, Stiemsma LT, Dimitriu PA, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci Transl Med, 2015, 7(307): 307ra152. |
| 46. | Stiemsma LT, Turvey SE. Asthma and the microbiome: defining the critical window in early life. Allergy Asthma Clin Immunol, 2017, 13: 3. |
| 47. | Ege MJ, Bieli C, Rrei R, et al. Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children. J Allergy Clin Immunol, 2006, 117(4): 817-823. |
- 1. 中华医学会呼吸系病学会哮喘学组. 支气管哮喘的定义、诊断、严重度分级及疗效判断标准 (修正方案). 中华结核和呼吸杂志, 1993, 16(1): 9-10.
- 2. 中华医学会呼吸病学分会. 支气管哮喘防治指南 (支气管哮喘的定义、诊断、治疗、疗效判断标准及教育和管理方案). 中华结核和呼吸杂志, 1997, 20(5): 261-267.
- 3. 中华医学会呼吸病学分会. 支气管哮喘防治指南 (支气管哮喘的定义、诊断、治疗、及教育和管理方案). 中华结核和呼吸杂志, 2003, 26(23): 132-138.
- 4. 中华医学会呼吸病学分会哮喘学组. 支气管哮喘防治指南 (支气管哮喘的定义、诊断、治疗及管理方案). 中华结核和呼吸杂志, 2008, 31(3): 177-185.
- 5. 中华医学会呼吸病分会哮喘学组. 支气管哮喘防治指南 (2016 年版). 中华结核和呼吸杂志, 2016, 39(9): 675-697.
- 6. 中华医学会呼吸病分会哮喘学组. 支气管哮喘控制的中国专家共识. 中华内科杂志, 2013, 52(5): 440-443.
- 7. 中华医学会呼吸病分会哮喘学组, 中国哮喘联盟. 支气管哮喘急性发作评估及处理. 中国专家共识. 中华内科杂志, , 2018, 57(1): 4-14.
- 8. 中华医学会呼吸病分会哮喘学组. 重症哮喘诊断与处理中国专家共识. 中华结核和呼吸杂志, 2017, 40(11): 813-829.
- 9. 中华医学会呼吸病分会哮喘学组. 难治性哮喘诊断与处理专家共识. 中华结核和呼吸杂志, 2010, 33(7): 572-577.
- 10. 中华医学会呼吸病分会哮喘学组. 支气管哮喘患者自我管理中国专家共识. 中华结核和呼吸杂志, 2018, 41(3): 171-178.
- 11. 苏楠, 林江涛, 刘国梁, 等. 我国 8 省市支气管哮喘患者控制水平的流行病学调查. 中华内科杂志, 2014, 53(8): 601-606.
- 12. 林江涛, 王文巧, 周新, 等. 我国 30 个省市城区门诊支气管哮喘患者控制水平的调查结果. 中华结核和呼吸杂志, 2017, 40(7): 494-498.
- 13. 林江涛, 王文巧, 周新, 等. 我国十城市支气管哮喘控制和疾病管理及患者认知水平的变化. 中华结核和呼吸杂志, 2018, 41(3): 191-195.
- 14. Katz LE, Gleich GJ, Hartley BF, et al. Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma. Ann Am Throac Soc, 2014, 11(4): 531-536.
- 15. Chung KF, Wenzel SE, Brozek JL, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J, 2014, 43(2): 343-373.
- 16. 陈荣昌. 呼吸与危重症医学 2016-2017. 北京: 人民卫生出版社, 2017, 123-126.
- 17. Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma (GINA) 2017.
- 18. Fanta CH. Asthma. N Engl J Med, 2009, 360(10): 1002-1014.
- 19. Bareman ED, Boushey HA, Bousquet J, et al. Can guideline-defined asthma control be achieved? The gaining optimal asthma control study. Am J Respir Crit Care Med, 2004, 170(8): 836-844.
- 20. Masoli M, Fabian D, Holt S, et al. The global burden of asthma: executive summary of the GINA Dissemination Committee Report. Allergy, 2004, 59(5): 469-478.
- 21. Roche WR, Beasley R, Williams JH, et al. Subepithelial fibrosis in the bronchi of asthmatics. Lancet, 1989, 1: 520-524.
- 22. Aikawa T, Shimura S, Sasaki H, et al. Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. Chest, 1992, 101: 916-921.
- 23. Tanaka H, Yamada G, Sakai T, et al. Increased airway vascularity in newly diagnosed asthma using a high-magnification bronchovideoscope. Am J Respir Crit Care Med, 2003, 168(12): 1495-1499.
- 24. Holgate ST, Wilson JR, Howarth PH. New insights into airway inflammation by endobronchial biopsy. Am Rev Respir Dis, 1992, 145(Suppl): S2-S6.
- 25. Redington AE, Madden J, Frew AJ, et al. Transforming growth factor-β1 in asthma: measurement in bronchoalveolar lavage fluid. Am J Respir Crit Care Med, 1997, 156(2 Pt 1): 642-647.
- 26. Minshall EM, Leung DY, Martin RJ, et al. Eosinophil-associated TGF-βl mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol, 1997, 17(3): 326-333.
- 27. Childhood Asthma Management Program Research Group, Szefler S, Weiss S, et al. Long-term effects of budesonide or nedocromil in children with asthma. N Engl J Med, 2000, 343: 1054-1063.
- 28. Holgate ST. The airway epithelium is central to the pathogenesis of asthma. Allergol Int, 2008, 57(1): 1-10.
- 29. Holgate ST, Davies DE, Lackie PM, et al. Epithelial-mesenchymal interactions in the pathogenesis of asthma. J. Allergy Clin Immunol, 2000, 105: 193-204.
- 30. Martinez FD, Wright AL, Taussig LM, et al. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med, 1995, 332(3): 133-138.
- 31. Hafkamp-de Groen E, Lingsma HF, Caudri D, et al. Predicting asthma in preschool children with asthma-like symptoms: validating and updating the PIAMA risk score. J Allergy Clin Immunol, 2013, 132(6): 1303-1310.
- 32. Amin P, Levin L, Epstein T, et al. Optimum predictors of childhood asthma: persistent wheeze or the asthma predictive index?. J Allergy Clin Immunol Pract, 2014, 2(6): 709-715.
- 33. Rodriguez-Martinez CE, Sossa-Briceno MP, Castro-Rodriguez JA. Factors predicting persistence of early wheezing through childhood and adolescence: a systematic review of the literature. J Astham Allergy, 2017, 10: 83-98.
- 34. Caudri D, Wijga A, A Schipper CM, et al. Predicting the long-term prognosis of children with symptoms suggestive of asthma at preschool age. J Allergy Clin Immunol, 2009, 124(5): 903-910.
- 35. Rubner FJ, Jackson DJ, Evans MD, et al. Early life rhinovirus wheezing, allergic sensitization, and asthma risk at adolescence. J Allergy Clin Immunol, 2017, 139(2): 501-507.
- 36. Csonka P, Kaila M, Laippala P, et al. Wheezing in early life and asthma at school age: predictors of symptom persistence. Pediatr Allergy Immunol, 2000, 11(4): 225-229.
- 37. Stiemsma LT, Renolds LA, Turvey SE, et al. The hygiene hypothesis: current perspectives and future therapies. Immunotargets Ther, 2015, 4: 143-157.
- 38. Just J, Belfar S, Wanin S, et al. Impact of innate and environmental factors on wheezing persistence during childhood. J Asthma, 2010, 47(4): 412-416.
- 39. Alfvén T, Braun-Fahrländer C, Brunekdreef B, et al. Allergic diseases and atopic sensitization in children related to farming and anthroposophic lifestyle--the PARSIFAL study. Allergy, 2006, 61(4): 414-421.
- 40. von Mutius E. The microbial environment and its influence on asthma prevention in early life. J Allergy Clin Immunol, 2016, 137(3): 680.
- 41. Ege MJ, Mayer M, Normand AC, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med, 2011, 364(8): 701-709.
- 42. Shreiner A, Huffnagle GB, Noverr MC. The " Microflora Hypothesis” of allergic disease. Adv Exp Med Biol, 2008, 635: 113-134.
- 43. Chung KF. Airway microbial dysbiosis in asthmatic patients: a target for prevention and treatment?. J Allergy Clin Immunol, 2017, 139(4): 1071-1081.
- 44. Abrahamsson TR, Jakobsson HE, Andersson AF, et al. Low gut microbiota diversity in early infancy precedes asthma at school age. Clin Exp Allergy, 2014, 44(6): 842-850.
- 45. Arrieta MC, Stiemsma LT, Dimitriu PA, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci Transl Med, 2015, 7(307): 307ra152.
- 46. Stiemsma LT, Turvey SE. Asthma and the microbiome: defining the critical window in early life. Allergy Asthma Clin Immunol, 2017, 13: 3.
- 47. Ege MJ, Bieli C, Rrei R, et al. Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children. J Allergy Clin Immunol, 2006, 117(4): 817-823.