Sanqi Tongshu Capsule for Acute Idiopathic Facial Paralysis: A Clinical Controlled Trial_Chinese Journal of Evidence-Based Medicine

Authors：

LIU Jing , WU Jingfen , WEI Yongsheng

Department of neurology, Sichuan Academy of Medical Science & Sichuan Provencial People’s hospital, Chengdu 610041, China;

Corresponding author：

Keywords：

Acute idiopathic facial paralysis; Sanqi Tongshu capsule; Clinical controlled trial; House-Brackmann; Facial electroneurogram

DOI：

10.7507/1672-2531.20100079

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Objective 　To evaluate the effect of PNS on Idiopathic facial palsy.
Methods 　A total of 86 cases of acute idiopathic facial paralysis were randomly divided into the treatment group (PNS group, 44 cases), and the control group (42 cases). The basis of the two groups included hormone therapy, B vitamins, anti-viral treatment, as well as acupuncture and physical therapy, both in the incidence of 7 days to give the treatment. House-Brackmann facial nerve function classification and evaluation were used to determine clinical efficacy; ENoG line was tested before and after treatment.
Results 　Before H-B classification of facial nerve function, EnoG side of the latency and amplitude in the two groups were comparable. At 28 days after treatment, H-B scores for the treatment group and the control group were (2.33 ± 1.21) and (3.08 ± 1.35), respectively, and the two groups had significant differences (P lt;0.05); ENoG incubation period (2.46 ± 0.34) and amplitude (189 ± 67) of the treatment group were more than those of the control group; the incubation period (3.37 ± 0.49) and amplitude (131 ± 52) improved, and there were significant differences between the two groups (P lt;0.05). Comparison of efficacy of the two groups showed the total effective rate: 95.45% in the treatment group, 80.95% in the control group, and the efficacy of the treatment group was better than that of the control group (P lt;0.05).
Conclusion 　Sanqi tongshu, B vitamins, anti-virus, such as the acupuncture and physical therapy for the treatment of acute idiopathic facial paralysis have significant effect.

Citation： LIU Jing,WU Jingfen,WEI Yongsheng. Sanqi Tongshu Capsule for Acute Idiopathic Facial Paralysis: A Clinical Controlled Trial. Chinese Journal of Evidence-Based Medicine, 2010, 10(1): 30-32. doi: 10.7507/1672-2531.20100079 Copy

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1. House JW. Facial nerve grading systems. Lanyngoscope, 1983, 93(8): 1056-1069.
2. House JW, Brackmann DE. Facial nerve grading system. Otolaryngol Head Neck Surg, 1985, 93(2): 146-147．.
3. 吴江主. 神经病学. 北京: 人民卫生出版社, 2005, 12.
4. Wakisaka H, Hato N, Honda N, et al. Demyelination associated with HSV-1-induced facial paralysis. Exp Neurol, 2002, 178(1): 68-79.
5. 史文峰. 贝尔麻痹的病因学说和治疗方法回顾. 中国医药指南, 2008, 6(1): 3-5.
6. 吕伯实, 刘振兴, 李克赞, 等. 面神经麻痹的应用解剖学研究. 泰山医学院学报, 2000, 21(3): 195-197.
7. Campbell Karen E, Brundage JF. Effects of climate, latitude, and season on the incidence of Bell’s palsy in the US Armed Forces, October 1997 to September 1999. Am J Epidemiol, 2002, 156(1): 32-39.
8. 全世明, 高志强. 贝尔面瘫治疗指南. 国际耳鼻咽喉头颈外科杂志, 2006, 30(4): 274.
9. 王晓红, 张黎明, 韩梅, 等. 中西医结合治疗贝尔面瘫. 华西口腔医学杂志, 2004, 22(6): 211-213.
10. Cronin GW, Steenerson RL. The effectiveness of neuromuscular facial retraining combined with electromyography in facial paralysis rehabilitation. Otolaryngol Head Neck Surg, 2003, 128(4): 534-538.
11. 詹合琴, 李平法, 沈志强. 三七皂苷 Rg1 对大鼠脑血流量和小鼠微循环的影响及作用机制. 华西药学杂志, 2006, 21(2): 170-171.　.
12. 曹保文, 杜跃斌. 三七总皂苷对缺血性脑血管病血液流变学的影响. 人民军医, 2003, 46(12): 596-796.
13. 史以菊, 夏作理, 杨慧英, 等. 三七皂甙对大鼠系膜血管微循环的影响. 泰山医学院学报, 1998, 19(1): 7-10.
14. 李坚文, 刘军, 曾志涛, 等. 三七皂苷对大鼠高眼压RGCL神经元的保护作用. 中国基层医药, 2007, 14(7): 1113-1115.

Chinese Journal of Evidence-Based Medicine

Sanqi Tongshu Capsule for Acute Idiopathic Facial Paralysis: A Clinical Controlled Trial

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