Association of Myocardial Enzymes’ Changes with Critical Illness Score in Neonatal Infection_Chinese Journal of Evidence-Based Medicine

Authors：

DOU Li ,  XU Ding , WANG Fan

Department of Pediatrics, The Second Hospital of Lanzhou University, Lanzhou 730000, China;

Corresponding author：

XU Ding, Email: xud@lzu.edu.cn

Keywords：

Neonate; Infection; Critical illness scoring; Myocardial enzyme

DOI：

10.7507/1672-2531.20110092

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective 　To evaluate the relationship between the severity of neonatal infection and the activity change of cardiac enzyme.
Methods 　A total of 102 infectious neonates in NICU were evaluated with neonatal serious illness scoring system and then divided into non-critical, critical, and extremely-critical groups. The activity of such serum myocardial enzymes as AST, ALT, LDH, CK, and CKMB was tested in the first 24 hours on admission. Comparison between groups and analyses were conducted.
Resultes 　Myocardial enzyme of the critical and extremely-critical groups was obviously higher than that of the non-critical group (P lt;0.01).
Conclusion 　 The serious illness score of infectious neonates is closely associated with the activity change of myocardial enzyme and the level of serum myocardial enzymes has certain advantages in judging the myocardial injury and the disease severity of neonatal infection.

Citation： DOU Li,XU Ding,WANG Fan. Association of Myocardial Enzymes’ Changes with Critical Illness Score in Neonatal Infection. Chinese Journal of Evidence-Based Medicine, 2011, 11(5): 515-517. doi: 10.7507/1672-2531.20110092 Copy

1.	6 Schuchat A, Zywicki SS, DinsmoorMJ, et al . Risk factors and opportunities for prevention of early onset neonatal sepsis: a multicenter case control study. Pediatrics , 2000, 105 (1 Pt 1): 21-26.
2.	10 Zaninotto M, Mion MM, Novelb E, et al . Creatine-kinase MB mass: Age and sex-associated reference limits in two different platforms that use the same methord. Clin Chm Acta , 2009, 401(1-2): 162-164.
3.	中华医学会儿科分会急诊学组新生儿组. 新生儿危重评分法(草案). 中华儿科杂志, 2001, 39 (1): 42.
4.	王蒂, 李佳, 林艺. CK和CK-MB在急性心肌梗死诊断中的价值探讨. 中国现代医药杂志, 2010, 12(8): 20-23.
5.	王凤枝. 婴幼儿肺炎患儿心肌酶谱检测临床分析. 现代预防医学, 2010, 37(13): 2596-2597.
6.	金汉珍, 主编. 实用新生儿学. 第3版. 北京: 人民卫生出版社, 2001.
7.	中华医学会儿科学分会新生儿学组. 新生儿败血症诊疗方案. 中华儿科杂志, 2003, 41(12): 897-899.
8.	陈文彬, 潘祥林, 主编. 诊断学. 第7版. 北京: 人民卫生出版社, 2008.
9.	孟馥芬, 张建龙, 马琪. 脓毒血症过程中大鼠心功能及心肌酶指标的动态变化. 新疆医科大学学报, 2005, 28(2): 128-130.
10.	杜国振. 关于心肌酶谱作为急诊检验项目的必要性. 中外医疗, 2010, 17: 56.
11.	范维琥, 赵碧莲. 心肌损伤标志物在急性冠状动脉综合征的应用. 中国实用内科杂志, 2008, 28(1): 16-18.
12.	单若冰, 王晓亮, 谭丽群. 新生儿疾病危重度评分预测死亡风险比较. 中华急诊医学杂志, 2005, 14(4): 335-337.

1. 6 Schuchat A, Zywicki SS, DinsmoorMJ, et al . Risk factors and opportunities for prevention of early onset neonatal sepsis: a multicenter case control study. Pediatrics , 2000, 105 (1 Pt 1): 21-26.
2. 10 Zaninotto M, Mion MM, Novelb E, et al . Creatine-kinase MB mass: Age and sex-associated reference limits in two different platforms that use the same methord. Clin Chm Acta , 2009, 401(1-2): 162-164.
3. 中华医学会儿科分会急诊学组新生儿组. 新生儿危重评分法(草案). 中华儿科杂志, 2001, 39 (1): 42.
4. 王蒂, 李佳, 林艺. CK和CK-MB在急性心肌梗死诊断中的价值探讨. 中国现代医药杂志, 2010, 12(8): 20-23.
5. 王凤枝. 婴幼儿肺炎患儿心肌酶谱检测临床分析. 现代预防医学, 2010, 37(13): 2596-2597.
6. 金汉珍, 主编. 实用新生儿学. 第3版. 北京: 人民卫生出版社, 2001.
7. 中华医学会儿科学分会新生儿学组. 新生儿败血症诊疗方案. 中华儿科杂志, 2003, 41(12): 897-899.
8. 陈文彬, 潘祥林, 主编. 诊断学. 第7版. 北京: 人民卫生出版社, 2008.
9. 孟馥芬, 张建龙, 马琪. 脓毒血症过程中大鼠心功能及心肌酶指标的动态变化. 新疆医科大学学报, 2005, 28(2): 128-130.
10. 杜国振. 关于心肌酶谱作为急诊检验项目的必要性. 中外医疗, 2010, 17: 56.
11. 范维琥, 赵碧莲. 心肌损伤标志物在急性冠状动脉综合征的应用. 中国实用内科杂志, 2008, 28(1): 16-18.
12. 单若冰, 王晓亮, 谭丽群. 新生儿疾病危重度评分预测死亡风险比较. 中华急诊医学杂志, 2005, 14(4): 335-337.

Chinese Journal of Evidence-Based Medicine

Association of Myocardial Enzymes’ Changes with Critical Illness Score in Neonatal Infection

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