Use of Oral Anti-diabetic Drugs in Advanced Aged Patient with Diabetic Mellitus: A Community Health Centre-Based Survey_Chinese Journal of Evidence-Based Medicine

Authors：

WANG Le ¹ , XIAN Su ¹ , ZHAO Qian ² , JIANG Hongling ¹ , WANG Yi ¹ , LIAO Xiaoyang ² ,  WANG Weiwen ³

1. Cao Shi Yu He Community Health Centre of Qing Yang District, Chengdu 610031, China;2. Department of Family Medicine, West China Hospital, Sichuan University, Chengdu 610041, China;3. Chengdu Military General Hospital, Chengdu 610083, China;

Corresponding author：

WANG Weiwen, Email: weiwenwang32@hotmail.com

Keywords：

Advanced age; Diabetic mellitus; Community health centre; Oral anti-diabetic drug; Cross-sectional survey

DOI：

10.7507/1672-2531.20130243

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Abstract Full text Figures/Tables Video References Cited by

Objective 　To investigate the use of oral anti-diabetic drugs and sugar blood control situation in advanced aged patient with diabetic mellitus in a community health centre in order to provide references for rational drug use.
Methods 　A cross-sectional survey about oral anti-diabetic drugs was carried out in senile diabetic patients who visited the community health centre and established complete health documents voluntarily from February 2012 to February 2013.
Results 　There were 176 cases of advanced aged patients with type 2 diabetic mellitus, of which, 107 cases were female and 69 cases were male, whose age ranged from 80 to 94. Among 176 cases, there were 107 (60.80%) patients with type 2 diabetic mellitus combined with hypertension, chronic heart diseases, and stoke; 155 had oral anti-diabetic drugs (88.06%). 67.19% of patients who took one oral anti-diabetic drug chose α-glycosidase inhibitors, followed by sulfonylurea. 53.73% of patients who received combination therapy chose glycosidase inhibitors and sulfonylurea. For the treatment of anti-diabetic drugs, 73.68% of patients met the criteria (fasting blood sugar: no more than 8.0 mmol/L), with control rates of 73.56% for α-glycosidase inhibitors and 72.58% for sulfonylurea. More than half of the patients could not be evaluated for their glycosylated hemoglobin levels were not tested.
Conclusion 　Doctors working in community health centres should choose oral anti-diabetic drugs according to patients’ own conditions when treating advanced aged patients with diabetic mellitus in order to avoid adverse reaction such as hypoglycemia. Glycosidase inhibitors are the mostly used drug in the community health centre because it is safe with less adverse reaction when used in senile people and it could ideally control their blood sugara.

Citation： WANG Le,XIAN Su,ZHAO Qian,JIANG Hongling,WANG Yi,LIAO Xiaoyang,WANG Weiwen. Use of Oral Anti-diabetic Drugs in Advanced Aged Patient with Diabetic Mellitus: A Community Health Centre-Based Survey. Chinese Journal of Evidence-Based Medicine, 2013, 13(12): 1413-1416. doi: 10.7507/1672-2531.20130243 Copy

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3.	易景娜, 陈利群, 贾守梅, 等. 390名社区居家高龄老年人生活质量现状及影响因素分析. 全科护理, 2011, 9(11): 2921-2924.
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11.	谢罄睿, 王洪权. 二甲双胍分别联合不同降糖药治疗2型糖尿病的疗效观察. 中国民康医学, 2010, 22(18): 2329-2393.
12.	. 邓海鸥, 林凯, 高国栋, 等. 高龄2型糖尿病住院患者抗高血糖药物治疗情况分析. 南方医科大学学报, 2008, 28(11): 2081-2082.
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14.	谭淑清, 王淑云. 社区糖尿病药物管理. 中国现代药物应用, 2011, 5(15): 50-51.
15.	魏丽文. 社区糖尿病用药干预思路. 中国社区医师·医学专业, 2011, 13(21): 15-17.

1. 催严格, 胡斌. 关于2型糖尿病处方用药的调查分析. 中外医学研究, 2012, 10(29): 152-153.
2. 孙艳荪, 乔珊, 钟霞, 等. 甘精胰岛素联合阿卡波糖治疗高龄老年2型糖尿病29例. 中国实用医刊, 2011, 38(7): 79-80.
3. 易景娜, 陈利群, 贾守梅, 等. 390名社区居家高龄老年人生活质量现状及影响因素分析. 全科护理, 2011, 9(11): 2921-2924.
4. 中华医学会糖尿病学分会. 中国２型糖尿病防治指南(2010年版). 中国糖尿病杂志, 2011, 20(36): S2-S37.
5. 中华医学会内分泌学分会. 中国成人2型糖尿病HbA1c控制目标的专家共识. 中华内分泌代谢杂志, 2011, 27(5): 371-374.
6. 何永静. 老年糖尿病并发症的临床分析. 当代医学, 2012, 18(294): 53-54.
7. 曹辉, 周艳成, 张旻, 等. 老年糖尿病低血糖症42例临床分析. 内科, 2009, 4(3): 458-459.
8. 纪立农, 吴晶, 陈颖丽, 等. 中国大中城市2型糖尿病降糖药物治疗患者药物使用调查分析. 中国药学杂志, 2012, 47(9): 736-738.
9. 李果. 再谈糖苷酶抑制剂在糖尿病防治中的临床应用. 实用糖尿病杂志, 2012, 8(2): 6-8.
10. 石瑾. 2型糖尿病治疗的基础用药——磺脲类药物概述. 药物流行病学杂志, 2012, 21(6): 303-305.
11. 谢罄睿, 王洪权. 二甲双胍分别联合不同降糖药治疗2型糖尿病的疗效观察. 中国民康医学, 2010, 22(18): 2329-2393.
12. . 邓海鸥, 林凯, 高国栋, 等. 高龄2型糖尿病住院患者抗高血糖药物治疗情况分析. 南方医科大学学报, 2008, 28(11): 2081-2082.
13. 李筱, 杨宗霞, 李幼平, 等. 我国示范乡镇卫生院基本药物循证评价与遴选之十九: 糖尿病. 中国循证医学杂志, 2012, 12(8): 1017-1023.
14. 谭淑清, 王淑云. 社区糖尿病药物管理. 中国现代药物应用, 2011, 5(15): 50-51.
15. 魏丽文. 社区糖尿病用药干预思路. 中国社区医师·医学专业, 2011, 13(21): 15-17.

Chinese Journal of Evidence-Based Medicine

Use of Oral Anti-diabetic Drugs in Advanced Aged Patient with Diabetic Mellitus: A Community Health Centre-Based Survey

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