Research Status and Development Methods of Cochrane Overviews: A Survey_Chinese Journal of Evidence-Based Medicine

Authors：

 GAOHong-yang , ZHAOYang , GAORui ,  LIBo

Institute of Clinical Pharmacology, Xiyuan Hospital, CACMS, Beijing 100091, China;

Corresponding author：

LIBo, Email: lb1922@126.com

Keywords：

Cochrane overview; Systematic review; Indirect comparison; Network meta-analysis; AMSTAR; GRADE

DOI：

10.7507/1672-2531.20140242

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the status of research and development methods of Cochrane overviews. Methods The Cochrane Library and PubMed were searched up to March 2014 to identify Cochrane overviews. According to the inclusion and exclusion criteria, two reviewers independently screened literature, extracted data, and assessed and analyzed search strategy, quality assessment method, data analysis, and study results. Results A total of 18 Cochrane overviews were included. Among them, 4 (22.2%) overviews included formal statistical indirect comparison; 8 (44.4%) included only results from direct comparison; 6 (33.4%) only systematically analyzed current studies without data pooling; 12 (66.7%) only searched The Cochrane Library, while 6 (33.3%) expanded search to other databases; 14 (77.8%) applied the AMSTAR tool to assess methodological quality of included literature; 12 (66.7%) applied the GRADE system to assess the quality of evidence; and 9 (50%) yielded new outcomes. Conclusion Currently, the development and reporting standards of Cochrane overviews are still immature. Investigators should choose proper methods based on research objectives when developing Cochrane overviews.

Citation： GAOHong-yang, ZHAOYang, GAORui, LIBo. Research Status and Development Methods of Cochrane Overviews: A Survey. Chinese Journal of Evidence-Based Medicine, 2014, 14(12): 1514-1519. doi: 10.7507/1672-2531.20140242 Copy

1.	Becker LA, Oxman AD. Overviews of reviews. Cochrane Handbook for Systematic Reviews of Interventions. John Wiley & Sons:Chichester, 2008:607-31.
2.	Singh JA, Christensen R, Wells GA, et al. Biologics for rheumatoid arthritis:an overview of Cochrane reviews. Cochrane Database Syst Rev, 2009, (4):CD007848.
3.	Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0[updated March 2011]. The Cochrane Collaboration, 2011. Available at:www.cochrane-handbook.org.
4.	刘雅莉, 袁金秋, 杨克虎, 等.系统评价再评价的制作方法简介及相关资料分析.中国循证儿科杂志, 2011, (1):58-64.
5.	Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses:the PRISMA statement. International Journal of Surgery, 2010, 8(5):336-341.
6.	Shea BJ, Grimshaw JM, Wells GA, et al. Development of AMSTAR:a measurement tool to assess the methodological quality of systematic reviews. BMC medical research methodology, 2007, 7(1):10.
7.	Cates Christopher J, Oleszczuk M, Stovold E, et al. Safety of regular formoterol or salmeterol in children with asthma:an overview of Cochrane reviews. Cochrane Database Syst Rev, 2012, (10):CD010005.
8.	Singh JA, Wells GA, CR, et al. Adverse effects of biologics:a network meta-analysis and Cochrane overview. Cochrane Database Syst Rev, 2011, (2):CD008794.
9.	Cahill K, Stevens S, Perera R, et al. Pharmacological interventions for smoking cessation:an overview and network meta-analysis. Cochrane Database Syst Rev, 2013, (5):CD009329.
10.	O'connell NE, Wand BM, Mcauley J, et al. Interventions for treating pain and disability in adults with complex regional pain syndrome-an overview of systematic reviews. Cochrane Database Syst Rev, 2013, (4):CD009416.
11.	Moore RA, Derry S, Mcquay HJ, et al. Single dose oral analgesics for acute postoperative pain in adults. Cochrane Database Syst Rev, 2011, (9):CD008659.
12.	Guay J, Choi P, Suresh S, et al. Neuraxial blockade for the prevention of postoperative mortality and major morbidity:an overview of Cochrane systematic reviews. Cochrane Database Syst Rev, 2014, (1):CD010108.
13.	Amato L, Minozzi S, Davoli M. Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome. Cochrane Database Syst Rev, 2011, (6):CD008537.
14.	Wiffen PJ, Derry S, Moore RA, et al. Antiepileptic drugs for neuropathic pain and fibromyalgia-an overview of Cochrane reviews. Cochrane Database Syst Rev, 2013, (11):CD010567.
15.	Cates CJ, Wieland LS, Oleszczuk M, et al. Safety of regular formoterol or salmeterol in adults with asthma:an overview of Cochrane reviews. Cochrane Database Syst Rev, 2014, (2):CD010314.
16.	Keus F, Gooszen HG, Van LCJHM. Open, small-incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato-Biliary Group reviews. Cochrane Database Syst Rev, 2010, (1):CD008318.
17.	Farquhar C, Rishworth JR, Brown J, et al. Assisted reproductive technology:an overview of Cochrane Reviews. Cochrane Database Syst Rev, 2013, (8):CD010537.
18.	Flodgren G, Eccles MP, Shepperd S, et al. An overview of reviews evaluating the effectiveness of financial incentives in changing healthcare professional behaviours and patient outcomes. Cochrane Database Syst Rev, 2011, (7):CD009255.
19.	Gill P J, Wang KY, Mant D, et al. The evidence base for interventions delivered to children in primary care:an overview of cochrane systematic reviews. PLoS One, 2011, 6(8):e23051.
20.	Jones L, Othman M, Dowswell T, et al. Pain management for women in labour:an overview of systematic reviews. Cochrane Database Syst Rev, 2012, (3):CD009234.
21.	Ryan R, Santesso N, Hill S, et al. Consumer-oriented interventions for evidence-based prescribing and medicines use:an overview of systematic reviews. Cochrane Database Syst Rev, 2011, (5):CD007768.
22.	Brown J, Farquhar C. Endometriosis:an overview of Cochrane Reviews. Cochrane Database Syst Rev, 2014, (3):CD009590.
23.	Payne C, Wiffen PJ, Martin S. Interventions for fatigue and weight loss in adults with advanced progressive illness. Cochrane Database Syst Rev, 2012, (1):CD008427.
24.	Wells GA, Sulta L, Khan M, et al. Indirect Evidence:Indirect Treatment Comparisons in Meta-analysis. Ottawa:Canadian Agency for Drugs and Technologies in Health, 2009:1-94, a1-a.
25.	Li L, Sun T, Han D, et al. What are the reporting and methodological qualities of network meta-analysis? Poster presentation at the 19th Cochrane Colloquium; 2011 Oct 19-22; Madrid, Spain[abstract]. Cochrane Database of Systematic Reviews, Supplement. 2011:123.
26.	Shea BJ, Hamel C, Wells GA, et al. AMSTAR is a reliable and valid measurement tool to assess the methodological quality of systematic reviews. J Clin Epidemiol, 2009, 62(10):1013-1020.
27.	Bucher HC, Guyatt GH, Griffith LE, et al. The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials. J Clin Epidemiol, 1997, 50(6):683-691.
28.	Caldwell DM, Ades AE, Higgins JP. Simultaneous comparison of multiple treatments:combining direct and indirect evidence. BMJ, 2005, 331(7521):897-900.
29.	Salanti G. Indirect and mixed-treatment comparison, network, or multiple-treatments meta-analysis:many names, many benefits, many concerns for the next generation evidence synthesis tool. Research Synthesis Methods, 2012, 3(2):80-97.
30.	胡晶, 杨智荣, 詹思延.间接比较和多种干预措施比较的方法学及应用.中国循证儿科杂志, 2011, 6(6):456-459.
31.	刘鸣, 杨杰, 王一平.对循证指南制定方法与临床应用的新思考.中国循证医学杂志, 2009, 9(2):127-128.
32.	杨克虎, 刘雅莉, 袁金秋, 等.发展和完善中的系统评价再评价.中国循证儿科杂志, 2011, (1):54-57.

1. Becker LA, Oxman AD. Overviews of reviews. Cochrane Handbook for Systematic Reviews of Interventions. John Wiley & Sons:Chichester, 2008:607-31.
2. Singh JA, Christensen R, Wells GA, et al. Biologics for rheumatoid arthritis:an overview of Cochrane reviews. Cochrane Database Syst Rev, 2009, (4):CD007848.
3. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0[updated March 2011]. The Cochrane Collaboration, 2011. Available at:www.cochrane-handbook.org.
4. 刘雅莉, 袁金秋, 杨克虎, 等.系统评价再评价的制作方法简介及相关资料分析.中国循证儿科杂志, 2011, (1):58-64.
5. Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses:the PRISMA statement. International Journal of Surgery, 2010, 8(5):336-341.
6. Shea BJ, Grimshaw JM, Wells GA, et al. Development of AMSTAR:a measurement tool to assess the methodological quality of systematic reviews. BMC medical research methodology, 2007, 7(1):10.
7. Cates Christopher J, Oleszczuk M, Stovold E, et al. Safety of regular formoterol or salmeterol in children with asthma:an overview of Cochrane reviews. Cochrane Database Syst Rev, 2012, (10):CD010005.
8. Singh JA, Wells GA, CR, et al. Adverse effects of biologics:a network meta-analysis and Cochrane overview. Cochrane Database Syst Rev, 2011, (2):CD008794.
9. Cahill K, Stevens S, Perera R, et al. Pharmacological interventions for smoking cessation:an overview and network meta-analysis. Cochrane Database Syst Rev, 2013, (5):CD009329.
10. O'connell NE, Wand BM, Mcauley J, et al. Interventions for treating pain and disability in adults with complex regional pain syndrome-an overview of systematic reviews. Cochrane Database Syst Rev, 2013, (4):CD009416.
11. Moore RA, Derry S, Mcquay HJ, et al. Single dose oral analgesics for acute postoperative pain in adults. Cochrane Database Syst Rev, 2011, (9):CD008659.
12. Guay J, Choi P, Suresh S, et al. Neuraxial blockade for the prevention of postoperative mortality and major morbidity:an overview of Cochrane systematic reviews. Cochrane Database Syst Rev, 2014, (1):CD010108.
13. Amato L, Minozzi S, Davoli M. Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome. Cochrane Database Syst Rev, 2011, (6):CD008537.
14. Wiffen PJ, Derry S, Moore RA, et al. Antiepileptic drugs for neuropathic pain and fibromyalgia-an overview of Cochrane reviews. Cochrane Database Syst Rev, 2013, (11):CD010567.
15. Cates CJ, Wieland LS, Oleszczuk M, et al. Safety of regular formoterol or salmeterol in adults with asthma:an overview of Cochrane reviews. Cochrane Database Syst Rev, 2014, (2):CD010314.
16. Keus F, Gooszen HG, Van LCJHM. Open, small-incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato-Biliary Group reviews. Cochrane Database Syst Rev, 2010, (1):CD008318.
17. Farquhar C, Rishworth JR, Brown J, et al. Assisted reproductive technology:an overview of Cochrane Reviews. Cochrane Database Syst Rev, 2013, (8):CD010537.
18. Flodgren G, Eccles MP, Shepperd S, et al. An overview of reviews evaluating the effectiveness of financial incentives in changing healthcare professional behaviours and patient outcomes. Cochrane Database Syst Rev, 2011, (7):CD009255.
19. Gill P J, Wang KY, Mant D, et al. The evidence base for interventions delivered to children in primary care:an overview of cochrane systematic reviews. PLoS One, 2011, 6(8):e23051.
20. Jones L, Othman M, Dowswell T, et al. Pain management for women in labour:an overview of systematic reviews. Cochrane Database Syst Rev, 2012, (3):CD009234.
21. Ryan R, Santesso N, Hill S, et al. Consumer-oriented interventions for evidence-based prescribing and medicines use:an overview of systematic reviews. Cochrane Database Syst Rev, 2011, (5):CD007768.
22. Brown J, Farquhar C. Endometriosis:an overview of Cochrane Reviews. Cochrane Database Syst Rev, 2014, (3):CD009590.
23. Payne C, Wiffen PJ, Martin S. Interventions for fatigue and weight loss in adults with advanced progressive illness. Cochrane Database Syst Rev, 2012, (1):CD008427.
24. Wells GA, Sulta L, Khan M, et al. Indirect Evidence:Indirect Treatment Comparisons in Meta-analysis. Ottawa:Canadian Agency for Drugs and Technologies in Health, 2009:1-94, a1-a.
25. Li L, Sun T, Han D, et al. What are the reporting and methodological qualities of network meta-analysis? Poster presentation at the 19th Cochrane Colloquium; 2011 Oct 19-22; Madrid, Spain[abstract]. Cochrane Database of Systematic Reviews, Supplement. 2011:123.
26. Shea BJ, Hamel C, Wells GA, et al. AMSTAR is a reliable and valid measurement tool to assess the methodological quality of systematic reviews. J Clin Epidemiol, 2009, 62(10):1013-1020.
27. Bucher HC, Guyatt GH, Griffith LE, et al. The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials. J Clin Epidemiol, 1997, 50(6):683-691.
28. Caldwell DM, Ades AE, Higgins JP. Simultaneous comparison of multiple treatments:combining direct and indirect evidence. BMJ, 2005, 331(7521):897-900.
29. Salanti G. Indirect and mixed-treatment comparison, network, or multiple-treatments meta-analysis:many names, many benefits, many concerns for the next generation evidence synthesis tool. Research Synthesis Methods, 2012, 3(2):80-97.
30. 胡晶, 杨智荣, 詹思延.间接比较和多种干预措施比较的方法学及应用.中国循证儿科杂志, 2011, 6(6):456-459.
31. 刘鸣, 杨杰, 王一平.对循证指南制定方法与临床应用的新思考.中国循证医学杂志, 2009, 9(2):127-128.
32. 杨克虎, 刘雅莉, 袁金秋, 等.发展和完善中的系统评价再评价.中国循证儿科杂志, 2011, (1):54-57.

Chinese Journal of Evidence-Based Medicine

Research Status and Development Methods of Cochrane Overviews: A Survey

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