The analysis of changes and causes of respiratory diseases prevalence and lung function of school-age children in Chongqing in the past 25 years_Chinese Journal of Evidence-Based Medicine

Authors：

LI Wenyan ¹ ,  LIU Qin ¹ , CHEN Yiwen ¹ , YANG Bo ¹ , HUANG Xin ¹ , LI Yueyue ¹ , ZHANG Junfeng ²

1. School of Public Health and Management, Research Center for Medicine and Social Development, Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, P.R.China;
2. Nicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, NC 27708, USA;

Corresponding author：

LIU Qin, Email: liuqin81622@163.com

Keywords：

Air quality; Nutrition and exercise; Children; Respiratory disease; Pulmonary function; Survey

DOI：

10.7507/1672-2531.201811027

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objectives To investigate the prevalence of respiratory diseases and lung function of school-age children in Chongqing and to compare them with that of children in 25 years ago and to explore the possible causes of this change.Methods According to the air quality data of Chongqing from 1998 to 2016, the annual variation of air quality days and pollutant concentrations were plotted. 2 126 school-age children in two districts of Chongqing were selected by random cluster sampling for questionnaires. 771 children were randomly selected from the children who completed the questionnaire for pulmonary function tests. The results were compared with that of 25 years ago.Results From 1998 to 2016, the number of days with good air quality in Chongqing increased annually, and the concentration of SO₂ decreased significantly. The main air pollution composition changed from SO₂ to PM₁₀ and PM_2.5. The prevalence of bronchitis (P<0.05) was higher than that of 25 years ago. After adjusting for confounding factors by multivariate logistic regression, the OR value of bronchitis in children was 1.667 (P<0.05) compared with 25 years ago. After adjusting for age, sex, height and weight by multiple linear regression, the results showed that the subjects' lung function indexes (FVC, FEV₁, PEF and FEV₃) were lower than that of 25 years ago. In this survey, there were differences in lung function indexes between children with different frequency of eating fruits and dairy products (P<0.05), and those with high frequency consumption were higher than low frequency. In terms of exercise time, subjects exercising ≥1 hour/day had greater FVC and FEV₃ values than those exercising <1 hour/day (P<0.05).Conclusions The overall air quality in Chongqing has improved from 1998 to 2016; The respiratory health of children has decreased when compared with that of 25 years ago. Changes in the composition of air pollutants may endanger children's respiratory health, and fruit and dairy foods and exercise may be protective factors for children's respiratory health.

Citation： LI Wenyan, LIU Qin, CHEN Yiwen, YANG Bo, HUANG Xin, LI Yueyue, ZHANG Junfeng. The analysis of changes and causes of respiratory diseases prevalence and lung function of school-age children in Chongqing in the past 25 years. Chinese Journal of Evidence-Based Medicine, 2019, 19(3): 281-286. doi: 10.7507/1672-2531.201811027 Copy

1.	Salvi S. Health effects of ambient air pollution in children. Paediatr Respir Rev, 2007, 8(4): 275-280.
2.	岳春兰, 田执梁. 空气污染与儿童哮喘发病机制的研究进展. 中国儿童保健杂志, 2018, 5(26): 510-517.
3.	唐靖媛, 夏茵茵, 唐旭, 等. 重庆市区不同污染水平地区大气可吸入颗粒物对儿童呼吸系统影响的抽样调查. 第三军医大学学报, 2015, 37(21): 2195-2198.
4.	唐旭, 黄为, 代华, 等. 重庆市不同大气污染水平地区学龄儿童呼吸系统症状及肺功能的比较. 第三军医大学学报, 2017, 34(5): 415-420.
5.	彭中贵, 陈军, 张毅, 等. 重庆大气污染与儿童肺功能横截面研究. 中国环境监测, 2001, 17(7): 98-102.
6.	彭中贵, 张毅, 陈军, 等. 重庆大气环境质量与儿童肺功能的前瞻性研究. 中国环境监测, 2001, 17(7): 87-90.
7.	李九彬, 王建力. 2001~2011 年重庆市空气质量特征分析. 西南大学学报, 2013, 35(9): 145-153.
8.	何勇, 吴亚坤, 陈昌鸣, 等. 2001~2010 年重庆主城区空气质量变化趋势. 重庆交通大学学报, 2012, 31(5): 1058-1061.
9.	刘永祺, 李大鹏, 倪长健. 重庆市大气污染特征及其影响因素分析. 四川环境, 2009, 28(3): 28-32.
10.	李璐. 重庆市 2009~2014 年主城区大气环境变化分析与对策研究. 无限互联科技, 2015, 6(11): 85-89.
11.	魏复盛, 胡伟. 中国四城市空气污染及其对儿童呼吸健康影响的分析. 世界科技研究与发展, 2000, 22(3): 9-11.
12.	李剑东. 长沙市郊区大气可吸入颗粒物化学组分特性及源解析. 长沙: 中南大学, 2009.
13.	乔莎, 何平, 张爱华. 细颗粒物化学组成及对儿童呼吸系统健康的影响. 世界最新医学信息文摘, 2016, 16(54): 10-11.
14.	伍燕珍, 张金良, 赵秀阁, 等. 我国大气污染与儿童呼吸系统疾病和症状的关系. 环境与健康杂志, 2009, 26(6): 471-477.
15.	Gilliland FD, Berhane KT, Li YF, et al. Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. Am J Epidemiol, 2003, 158(6): 576-584.
16.	Romieu I, Barraza-Villarreal A, Escamilla-Núñez C, et al. Dietary intake, lung function and airway inflammation in Mexico city school children exposed to air pollutants. Respir Res, 2009, 10: 122.
17.	郭长江, 杨继军. 蔬菜、水果抗氧化作用的研究进展. 中国公共卫生, 2001, 17(1): 87-88.
18.	何启强, 杜琳, 黄子惠, 等. 膳食营养与学龄儿童呼吸系统健康的相关性研究. 中国预防医学杂志, 2009, 10(2): 115-119.
19.	刘和亮, 赵金垣. 氧化应激和肺损伤. 中国职业医学, 2002, 29(5): 49-51.
20.	马思远. 我国中小学生体质下降及其社会成因研究. 北京: 北京体育大学, 2012.
21.	Berntsen S, Wisløff T, Nafstad P, et al. Lung function increases with increasing level of physical activity in school children. Pediatr Exerc Sci, 2008, 20(4): 402-410.
22.	Ji J, Wang SQ, Liu YJ, et al. Physical activity and lung function growth in a cohort of Chinese school children: A Prospective Study. PLoS One, 2013, 8(6): e66098.
23.	Liu W, Huang C, Hu Y, et al. Associations of gestational and early life exposures to ambient air pollution with childhood respiratory diseases in Shanghai, China: a retrospective cohort study. Environ Int, 2016, (92-93): 284-93.
24.	Deng Q, Lu C, Norbäck D, et al. Early life exposure to ambient air pollution and childhood asthma in China. Environ Res, 2015, 143(Pt A): 83-92.
25.	龚伟, 娄畅, 王绍华. 北京市延庆区室内环境因素对学龄儿童呼吸系统健康影响的分析. 现代医学, 2016, 44(3): 277-283.
26.	Svendsen ER, Gonzales M, Commodore A. The role of the indoor environment: residential determinants of allergy, asthma and pulmonary function in children from a US-Mexico border community. Sci Total Environ, 2018, (616-617): 1513-1523.

1. Salvi S. Health effects of ambient air pollution in children. Paediatr Respir Rev, 2007, 8(4): 275-280.
2. 岳春兰, 田执梁. 空气污染与儿童哮喘发病机制的研究进展. 中国儿童保健杂志, 2018, 5(26): 510-517.
3. 唐靖媛, 夏茵茵, 唐旭, 等. 重庆市区不同污染水平地区大气可吸入颗粒物对儿童呼吸系统影响的抽样调查. 第三军医大学学报, 2015, 37(21): 2195-2198.
4. 唐旭, 黄为, 代华, 等. 重庆市不同大气污染水平地区学龄儿童呼吸系统症状及肺功能的比较. 第三军医大学学报, 2017, 34(5): 415-420.
5. 彭中贵, 陈军, 张毅, 等. 重庆大气污染与儿童肺功能横截面研究. 中国环境监测, 2001, 17(7): 98-102.
6. 彭中贵, 张毅, 陈军, 等. 重庆大气环境质量与儿童肺功能的前瞻性研究. 中国环境监测, 2001, 17(7): 87-90.
7. 李九彬, 王建力. 2001~2011 年重庆市空气质量特征分析. 西南大学学报, 2013, 35(9): 145-153.
8. 何勇, 吴亚坤, 陈昌鸣, 等. 2001~2010 年重庆主城区空气质量变化趋势. 重庆交通大学学报, 2012, 31(5): 1058-1061.
9. 刘永祺, 李大鹏, 倪长健. 重庆市大气污染特征及其影响因素分析. 四川环境, 2009, 28(3): 28-32.
10. 李璐. 重庆市 2009~2014 年主城区大气环境变化分析与对策研究. 无限互联科技, 2015, 6(11): 85-89.
11. 魏复盛, 胡伟. 中国四城市空气污染及其对儿童呼吸健康影响的分析. 世界科技研究与发展, 2000, 22(3): 9-11.
12. 李剑东. 长沙市郊区大气可吸入颗粒物化学组分特性及源解析. 长沙: 中南大学, 2009.
13. 乔莎, 何平, 张爱华. 细颗粒物化学组成及对儿童呼吸系统健康的影响. 世界最新医学信息文摘, 2016, 16(54): 10-11.
14. 伍燕珍, 张金良, 赵秀阁, 等. 我国大气污染与儿童呼吸系统疾病和症状的关系. 环境与健康杂志, 2009, 26(6): 471-477.
15. Gilliland FD, Berhane KT, Li YF, et al. Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. Am J Epidemiol, 2003, 158(6): 576-584.
16. Romieu I, Barraza-Villarreal A, Escamilla-Núñez C, et al. Dietary intake, lung function and airway inflammation in Mexico city school children exposed to air pollutants. Respir Res, 2009, 10: 122.
17. 郭长江, 杨继军. 蔬菜、水果抗氧化作用的研究进展. 中国公共卫生, 2001, 17(1): 87-88.
18. 何启强, 杜琳, 黄子惠, 等. 膳食营养与学龄儿童呼吸系统健康的相关性研究. 中国预防医学杂志, 2009, 10(2): 115-119.
19. 刘和亮, 赵金垣. 氧化应激和肺损伤. 中国职业医学, 2002, 29(5): 49-51.
20. 马思远. 我国中小学生体质下降及其社会成因研究. 北京: 北京体育大学, 2012.
21. Berntsen S, Wisløff T, Nafstad P, et al. Lung function increases with increasing level of physical activity in school children. Pediatr Exerc Sci, 2008, 20(4): 402-410.
22. Ji J, Wang SQ, Liu YJ, et al. Physical activity and lung function growth in a cohort of Chinese school children: A Prospective Study. PLoS One, 2013, 8(6): e66098.
23. Liu W, Huang C, Hu Y, et al. Associations of gestational and early life exposures to ambient air pollution with childhood respiratory diseases in Shanghai, China: a retrospective cohort study. Environ Int, 2016, (92-93): 284-93.
24. Deng Q, Lu C, Norbäck D, et al. Early life exposure to ambient air pollution and childhood asthma in China. Environ Res, 2015, 143(Pt A): 83-92.
25. 龚伟, 娄畅, 王绍华. 北京市延庆区室内环境因素对学龄儿童呼吸系统健康影响的分析. 现代医学, 2016, 44(3): 277-283.
26. Svendsen ER, Gonzales M, Commodore A. The role of the indoor environment: residential determinants of allergy, asthma and pulmonary function in children from a US-Mexico border community. Sci Total Environ, 2018, (616-617): 1513-1523.

Chinese Journal of Evidence-Based Medicine

The analysis of changes and causes of respiratory diseases prevalence and lung function of school-age children in Chongqing in the past 25 years

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content