Evidence-based evaluation of influencing factors, intervention measures and management mode of epilepsy patients in China_Journal of Epilepsy

Authors：

YANG Chunsong ^1,2 ,  ZHANG Lingli ^1,2 , YANG Yaya ^1,2 , TAO Qiuji ³ , YU Dan ³

1. Department of Pharmacy/Evidence-based Pharmacy Center, West China Second Hospital, Sichuan University, Chengdu 610041, China;
2. Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, China;
3. Department of Pediatric Neurology, West China Second Hospital, Sichuan University, Chengdu 610041, China;

Corresponding author：

ZHANG Lingli, Email: zhlingli@sina.com

Keywords：

Epilepsy; Self-management; Evidence-based evaluation

DOI：

10.7507/2096-0247.202304005

Video：

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Objective To systematically evaluate the influencing factors, intervention measures and management mode of epilepsy patients in China, so as to provide evidence support for ensuring the therapeutic effect of epilepsy patients. Methods PubMed, EMBASE, Cochrane Library, CBM, CNKI, VIP, Wanfang and other domestic and foreign databases were systematically searched, and the literature on influencing factors, intervention measures and management modes of self-management behavior of epilepsy patients in China was included. Descriptive methods were used to analyze the results. Results A total of 21 studies were included, including 2 studies on influencing factors, 14 studies on intervention measures and 5 studies on management mode. The participants of 20 studies is adult epilepsy patients, and one study is adolescent epilepsy aged 13 ~ 17, with a sample size of 40 ~ 327 cases and a median sample size of 70 cases. The results showed that self-management behavior is positively correlated with self-efficacy, bachelor degree or above, female and operation duration < 3 hours, and negatively correlated with 30 ~ 50 years old. The self-management behavior scale score, medication compliance, treatment satisfaction, quality of life, seizure frequency, symptom checklist, anxiety and depression score in the intervention group were better than those in the control group. After the intervention of self- management mode, the self-management score, treatment efficiency, quality of life and medication compliance of the intervention group were better than those of the control group. Conclusions The level of self-management of epilepsy patients in China is insufficient, and the influencing factors and intervention measures are single, lacking integrated intervention measures and management models based on different levels of individuals, families, medical system and society. It is suggested that the self-management model of epileptic patients should be constructed based on evidence to improve self-efficacy and self-management level.

Citation： YANG Chunsong, ZHANG Lingli, YANG Yaya, TAO Qiuji, YU Dan. Evidence-based evaluation of influencing factors, intervention measures and management mode of epilepsy patients in China. Journal of Epilepsy, 2023, 9(4): 300-305. doi: 10.7507/2096-0247.202304005 Copy

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2.	World Health Organization‎. Improving the lives of people with epilepsy: a technical brief. ‎2022.
3.	Samsonsen C, Reimers A, Bråthen G, et al. Nonadherence to treatment causing acute hospitalizations in people with epilepsy: an observational, prospective study. Epilepsia, 2014, 55(11): 125-128.
4.	Devinsky O, Ryvlin P, Friedman D. Preventing sudden unexpected death in epilepsy. JAMA Neurol, 2018, 75(5): 531-532.
5.	Allegrante JP, Wells MT, Peterson JC. Interventions to support behavioral self-management of chronic diseases. Annu Rev Public Health, 2019, 40: 127-146.
6.	Luedke MW, Blalock DV, Goldstein KM, et al. Self-management of epilepsy: a systematic review. Ann Intern Med, 2019, 171(2): 117-126.
7.	Fleeman N, Bradley PM, Panebianco M, et al. Care delivery and self-management strategies for children with epilepsy. Cochrane Database Syst Rev, 2022, 4(4): CD006245.
8.	Lewinski AA, Shapiro A, Gierisch JM, et al. Barriers and facilitators to implementation of epilepsy self-management programs: a systematic review using qualitative evidence synthesis methods. Syst Rev, 2020, 9(1): 92.
9.	Russ SA, Larson K, Halfon N. A national profile of childhood epilepsy and seizure disorder. Pediatrics, 2012, 129(2): 256-264.
10.	Wagner JL, Modi AC, Johnson EK, et al. Self-management interventions in pediatric epilepsy: what is the level of evidence? Epilepsia, 2017, 58（5）: 743-754.
11.	Smith G, Modi AC, Johnson EK, et al. Measurement in pediatric epilepsy self-management: a critical review. Epilepsia, 2018, 59(3): 509-522.
12.	张晓艳, 楚平华, 魏贵明. 癫痫患者自我效能与自我管理行为的相关性研究. 护理管理杂志, 2008, (1): 4-6.
13.	金莺, 陈蓓妮, 金笑言, 等. 上海华山医院神经外科围手术期癫痫患者自我管理能力影响因素分析. 复旦学报(医学版), 2023, 50(1): 108-113.
14.	王彩霞, 赵佳维, 王晓新, 等. 基于癫痫日记APP的远程干预应用于青少年癫痫患者的效果. 中西医结合护理(中英文), 2021, 7(4): 76-78.
15.	袁晓莉, 袁清. 健康教育对癫痫患者自我管理行为的影响. 慢性病学杂志, 2010, 12(7): 654-655.
16.	夏季, 任兴乾. 健康教育对癫痫患者自我管理行为的影响体会. 现代养生, 2016, (12): 208.
17.	胡铭, 杨秀华, 徐翠福, 等. 量化评估策略下护理干预对癫痫患者自我管理行为及生活质量的影响. 世界临床医学, 2018, 12(1): 45-46, 48.
18.	王晓娟, 胡永芳, 雍莉, 等. 成年癫痫患者自我管理干预研究. 护士进修杂志, 2012, 27(18): 1669-1672.
19.	刘秀英, 陈锁红, 费网华, 等. 叙事护理对成人癫痫病人不良情绪、自我管理能力、生活质量的影响研究. 全科护理, 2022, 20(4): 526-529.
20.	唐珊, 杨辉. 护理结局分类在原发性癫痫病人自我管理状况评价中的应用. 护理研究, 2015, 29(35): 4466-4467.
21.	阮丽芬, 周斯敏, 谢艳秋, 等. 护理结局分类在原发性癫痫患者自我管理状况评价中的应用价值研究. 中医临床研究, 2016, 8(12): 33-35.
22.	王影. 护理结局分类在原发性癫痫患者自我管理状况评价中的应用价值研究. 中国医药指南, 2016, 14(34): 200-201.
23.	钟志静. 护理结局分类在原发性癫痫患者自我管理状况评价中的应用价值研究. 实用临床护理学电子杂志, 2017, 2(18): 3-4.
24.	王靳君, 姚兰, 王莹, 等. 护理结局分类在原发性癫痫患者自我管理状况评价中的应用效果观察. 中国现代医生, 2017, 55(6): 154-156.
25.	陈小利. 护理结局分类在原发性癫痫患者自我管理状况评价中的效果. 当代临床医刊, 2021, 34(5): 106+85.
26.	邵春晓, 郑珊珊. 护理结局分类在原发性癫痫患者自我管理状况评价中的效果. 包头医学院学报, 2019, 35(03): 84-86.
27.	Yang Si, Xiaoqiang Xiao, Cai Xia, et al. Optimising epilepsy management with a smartphone application: a randomised controlled trial. Med J Aust, 2020, 212(6): 258-262.
28.	王鸣璐, 王环鑫, 刘世浩, 等. 基于治疗药物监测数据的癫痫自我管理移动应用程序的开发设计. 临床药物治疗杂志, 2019, 17(8): 86-89+92.
29.	刘春兰, 郭巧容, 何小青. 疾病自我管理模式对癫痫患者自理能力和生活质量的影响. 广东医学院学报, 2014, 32(3): 397-398.
30.	郭玉洁, 陈小利, 解紫晋, 等. 药物难治性癫痫患者迷走神经刺激术后自我管理模式的应用探讨. 癫痫与神经电生理学杂志, 2022, 31(6): 341-346.
31.	陈莎莎. 以互联网为基础自我行为管理模式用于癫痫患者的可行性研究. 护理实践与研究, 2020, 17(22): 43-45.
32.	Meiling Hu, Chenqi Zhang, Xiaoqiang Xiao, et al. Effect of intensive self-management education on seizure frequency and quality of life in epilepsy patients with prodromes or precipitating factors. Seizure, 2020, 78: 38-42.
33.	Fleeman N, Bradley PM. Care delivery and self management strategies for children with epilepsy. Cochrane Database Syst Rev, 2018, 3: CD006245.
34.	Orla Mooney, Aoife McNicholl, Veronica Lambert, et al. Self-management in children and young people with epilepsy: a systematic review and qualitative meta-synthesis. J Health Psychol, 2021, 26（1）: 126-139.

1. World Health Organization‎. Epilepsy: a public health imperative. 2019.
2. World Health Organization‎. Improving the lives of people with epilepsy: a technical brief. ‎2022.
3. Samsonsen C, Reimers A, Bråthen G, et al. Nonadherence to treatment causing acute hospitalizations in people with epilepsy: an observational, prospective study. Epilepsia, 2014, 55(11): 125-128.
4. Devinsky O, Ryvlin P, Friedman D. Preventing sudden unexpected death in epilepsy. JAMA Neurol, 2018, 75(5): 531-532.
5. Allegrante JP, Wells MT, Peterson JC. Interventions to support behavioral self-management of chronic diseases. Annu Rev Public Health, 2019, 40: 127-146.
6. Luedke MW, Blalock DV, Goldstein KM, et al. Self-management of epilepsy: a systematic review. Ann Intern Med, 2019, 171(2): 117-126.
7. Fleeman N, Bradley PM, Panebianco M, et al. Care delivery and self-management strategies for children with epilepsy. Cochrane Database Syst Rev, 2022, 4(4): CD006245.
8. Lewinski AA, Shapiro A, Gierisch JM, et al. Barriers and facilitators to implementation of epilepsy self-management programs: a systematic review using qualitative evidence synthesis methods. Syst Rev, 2020, 9(1): 92.
9. Russ SA, Larson K, Halfon N. A national profile of childhood epilepsy and seizure disorder. Pediatrics, 2012, 129(2): 256-264.
10. Wagner JL, Modi AC, Johnson EK, et al. Self-management interventions in pediatric epilepsy: what is the level of evidence? Epilepsia, 2017, 58（5）: 743-754.
11. Smith G, Modi AC, Johnson EK, et al. Measurement in pediatric epilepsy self-management: a critical review. Epilepsia, 2018, 59(3): 509-522.
12. 张晓艳, 楚平华, 魏贵明. 癫痫患者自我效能与自我管理行为的相关性研究. 护理管理杂志, 2008, (1): 4-6.
13. 金莺, 陈蓓妮, 金笑言, 等. 上海华山医院神经外科围手术期癫痫患者自我管理能力影响因素分析. 复旦学报(医学版), 2023, 50(1): 108-113.
14. 王彩霞, 赵佳维, 王晓新, 等. 基于癫痫日记APP的远程干预应用于青少年癫痫患者的效果. 中西医结合护理(中英文), 2021, 7(4): 76-78.
15. 袁晓莉, 袁清. 健康教育对癫痫患者自我管理行为的影响. 慢性病学杂志, 2010, 12(7): 654-655.
16. 夏季, 任兴乾. 健康教育对癫痫患者自我管理行为的影响体会. 现代养生, 2016, (12): 208.
17. 胡铭, 杨秀华, 徐翠福, 等. 量化评估策略下护理干预对癫痫患者自我管理行为及生活质量的影响. 世界临床医学, 2018, 12(1): 45-46, 48.
18. 王晓娟, 胡永芳, 雍莉, 等. 成年癫痫患者自我管理干预研究. 护士进修杂志, 2012, 27(18): 1669-1672.
19. 刘秀英, 陈锁红, 费网华, 等. 叙事护理对成人癫痫病人不良情绪、自我管理能力、生活质量的影响研究. 全科护理, 2022, 20(4): 526-529.
20. 唐珊, 杨辉. 护理结局分类在原发性癫痫病人自我管理状况评价中的应用. 护理研究, 2015, 29(35): 4466-4467.
21. 阮丽芬, 周斯敏, 谢艳秋, 等. 护理结局分类在原发性癫痫患者自我管理状况评价中的应用价值研究. 中医临床研究, 2016, 8(12): 33-35.
22. 王影. 护理结局分类在原发性癫痫患者自我管理状况评价中的应用价值研究. 中国医药指南, 2016, 14(34): 200-201.
23. 钟志静. 护理结局分类在原发性癫痫患者自我管理状况评价中的应用价值研究. 实用临床护理学电子杂志, 2017, 2(18): 3-4.
24. 王靳君, 姚兰, 王莹, 等. 护理结局分类在原发性癫痫患者自我管理状况评价中的应用效果观察. 中国现代医生, 2017, 55(6): 154-156.
25. 陈小利. 护理结局分类在原发性癫痫患者自我管理状况评价中的效果. 当代临床医刊, 2021, 34(5): 106+85.
26. 邵春晓, 郑珊珊. 护理结局分类在原发性癫痫患者自我管理状况评价中的效果. 包头医学院学报, 2019, 35(03): 84-86.
27. Yang Si, Xiaoqiang Xiao, Cai Xia, et al. Optimising epilepsy management with a smartphone application: a randomised controlled trial. Med J Aust, 2020, 212(6): 258-262.
28. 王鸣璐, 王环鑫, 刘世浩, 等. 基于治疗药物监测数据的癫痫自我管理移动应用程序的开发设计. 临床药物治疗杂志, 2019, 17(8): 86-89+92.
29. 刘春兰, 郭巧容, 何小青. 疾病自我管理模式对癫痫患者自理能力和生活质量的影响. 广东医学院学报, 2014, 32(3): 397-398.
30. 郭玉洁, 陈小利, 解紫晋, 等. 药物难治性癫痫患者迷走神经刺激术后自我管理模式的应用探讨. 癫痫与神经电生理学杂志, 2022, 31(6): 341-346.
31. 陈莎莎. 以互联网为基础自我行为管理模式用于癫痫患者的可行性研究. 护理实践与研究, 2020, 17(22): 43-45.
32. Meiling Hu, Chenqi Zhang, Xiaoqiang Xiao, et al. Effect of intensive self-management education on seizure frequency and quality of life in epilepsy patients with prodromes or precipitating factors. Seizure, 2020, 78: 38-42.
33. Fleeman N, Bradley PM. Care delivery and self management strategies for children with epilepsy. Cochrane Database Syst Rev, 2018, 3: CD006245.
34. Orla Mooney, Aoife McNicholl, Veronica Lambert, et al. Self-management in children and young people with epilepsy: a systematic review and qualitative meta-synthesis. J Health Psychol, 2021, 26（1）: 126-139.

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