目的 探讨白试验在肝切除手术中检测漏胆的价值。
方法 笔者所在医院2008年1月至2013年1月期间在肝切除手术中采用白试验联合干纱布擦拭法检测漏胆56例。即在肝切除手术操作末期,用干纱布擦拭法确认无漏胆后,经胆囊管或左右肝管插管注入5%无菌脂肪乳剂10~30mL,同时用手阻断远端胆总管。观察肝切除手术创面的白色液体渗出情况,对渗出白色液体处予以间断缝合。重复操作,至断面无白色液体渗出为止。
结果 56例患者经术中检测,发现漏胆17例(漏胆检出率为30.4%),每例发现漏胆1~6处(平均2.9处),术中均予以确切缝合以关闭漏胆处,且重复试验操作,证实均再无漏胆。术后发生漏胆2例(3.6%),经相应治疗后痊愈出院。全部患者出院后均随访3~6个月(平均3.8个月),无膈下积液或膈下感染病例发生。
结论 术中白试验能够发现漏胆的精确部位,不会污染肝切除手术创面,并能够无限次地重复试验,值得临床推广。
Citation:
王建新,蔡卫华,肖旭,王卫兵,陈骏,蔡邢峰. The Application of White Test for Detection of Bile Leakage at Liver Resection Margin During Liver Resection Surgery. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2013, 20(12): 1407-1409. doi:
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樊嘉, 王晓颖. 肝切除术后胆漏的处理[J]. 肝胆外科杂志, 2006, 14(4):243-244.
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Nadalin S, Li J, Lang H, et al. The white test:a new dye test for intraoperative detection of bile leakage during major liver rese-ction[J]. Arch Surg, 2008, 143(4):402-404.
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Shimada M, Takenaka K, Fujiwara Y, et al. Risk factors linked to postoperative morbidity in patients with hepatocellular carcinoma[J]. Br J Surg, 1998, 85(2):195-198.
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Nagano Y, Togo S, Tanaka K, et al. Risk factors and managementof bile leakage after hepatic resection[J]. World J Surg, 2003, 27(6):695-698.
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Ijichi M, Takayama T, Toyoda H, et al. Randomized trial of the usefulness of a bile leakage test during hepatic resection[J]. Arch Surg, 2000, 135(12):1395-1400.
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6. |
Erdogan D, Busch OR, van Delden OM, et al. Incidence and management of bile leakage after partial liver resection[J]. Dig Surg, 2008, 25(1):60-66.
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7. |
Capussotti L, Ferrero A, Viganò L, et al. Bile leakage and liver resection:where is the risk?[J]. Arch Surg, 2006, 141(7):690-694.
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董家鸿, 黄志强. 精准肝切除——21世纪肝脏外科新理念[J]. 中华外科杂志, 2009, 47(21):1601-1605.
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匡铭, 汤地, 王晔, 等. 三维手术模拟系统在肝癌患者精准肝切除中的应用[J]. 中国普外基础与临床杂志, 2011, 18(7):682-687.
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Lang H, Radtke A, Liu C, et al. Extended left hepatectomy—modified operation planning based on three-dimensional visuali-zation of liver anatomy[J]. Langenbecks Arch Surg, 2004, 389 (4):306-310.
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11. |
Taketomi A, Kitagawa D, Itoh S, et al. Trends in morbidity and mortality after hepatic resection for hepatocellular carcinoma:an institute’s experience with 625 patients[J]. J Am Coll Surg, 2007, 204(4):580-587.
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12. |
Boonstra EA, de Boer MT, Sieders E, et al. Risk factors for central bile duct injury complicating partial liver resection[J]. Br J Surg, 2012, 99(2):256-262.
|
13. |
樊嘉, 黄成. 原发性肝癌外科治疗的进展[J]. 中国普外基础与临床杂志, 2009, 16(4):257-260.
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14. |
董家鸿, 冷建军. 肝切除断面处理[J]. 肝胆外科杂志, 2008, 16(2):95-96.
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15. |
Tanaka S, Hirohashi K, Tanaka H, et al. Incidence and management of bile leakage after hepatic resection for malignant hepatic tumors[J]. J Am Coll Surg, 2002, 195(4):484-489.
|
- 1. 樊嘉, 王晓颖. 肝切除术后胆漏的处理[J]. 肝胆外科杂志, 2006, 14(4):243-244.
- 2. Nadalin S, Li J, Lang H, et al. The white test:a new dye test for intraoperative detection of bile leakage during major liver rese-ction[J]. Arch Surg, 2008, 143(4):402-404.
- 3. Shimada M, Takenaka K, Fujiwara Y, et al. Risk factors linked to postoperative morbidity in patients with hepatocellular carcinoma[J]. Br J Surg, 1998, 85(2):195-198.
- 4. Nagano Y, Togo S, Tanaka K, et al. Risk factors and managementof bile leakage after hepatic resection[J]. World J Surg, 2003, 27(6):695-698.
- 5. Ijichi M, Takayama T, Toyoda H, et al. Randomized trial of the usefulness of a bile leakage test during hepatic resection[J]. Arch Surg, 2000, 135(12):1395-1400.
- 6. Erdogan D, Busch OR, van Delden OM, et al. Incidence and management of bile leakage after partial liver resection[J]. Dig Surg, 2008, 25(1):60-66.
- 7. Capussotti L, Ferrero A, Viganò L, et al. Bile leakage and liver resection:where is the risk?[J]. Arch Surg, 2006, 141(7):690-694.
- 8. 董家鸿, 黄志强. 精准肝切除——21世纪肝脏外科新理念[J]. 中华外科杂志, 2009, 47(21):1601-1605.
- 9. 匡铭, 汤地, 王晔, 等. 三维手术模拟系统在肝癌患者精准肝切除中的应用[J]. 中国普外基础与临床杂志, 2011, 18(7):682-687.
- 10. Lang H, Radtke A, Liu C, et al. Extended left hepatectomy—modified operation planning based on three-dimensional visuali-zation of liver anatomy[J]. Langenbecks Arch Surg, 2004, 389 (4):306-310.
- 11. Taketomi A, Kitagawa D, Itoh S, et al. Trends in morbidity and mortality after hepatic resection for hepatocellular carcinoma:an institute’s experience with 625 patients[J]. J Am Coll Surg, 2007, 204(4):580-587.
- 12. Boonstra EA, de Boer MT, Sieders E, et al. Risk factors for central bile duct injury complicating partial liver resection[J]. Br J Surg, 2012, 99(2):256-262.
- 13. 樊嘉, 黄成. 原发性肝癌外科治疗的进展[J]. 中国普外基础与临床杂志, 2009, 16(4):257-260.
- 14. 董家鸿, 冷建军. 肝切除断面处理[J]. 肝胆外科杂志, 2008, 16(2):95-96.
- 15. Tanaka S, Hirohashi K, Tanaka H, et al. Incidence and management of bile leakage after hepatic resection for malignant hepatic tumors[J]. J Am Coll Surg, 2002, 195(4):484-489.