【Abstract】Objective To investigate the expressions of TNF-α and superoxide dismutase (SOD) mRNA in myocardium of rats with obstructive jaundice (OJ).
Methods The expressions of TNF-α and SOD mRNA were semi-quantitatively analyzed after amplification of cDNA in myocardium of the rats with OJ by RTPCR.
Results The expression of TNF-α mRNA increased and that of SOD mRNA decreased in the myocardium of rats with OJ. The level of plasm TNF-α increased and SOD synthesis in myocardium decreased.
Conclusion The injury of myocardium in
OJ is correlated with increasing expression of TNF-α mRNA and decreasing expression of SOD mRNA.
Citation：
GONG Peng,WANG Zhongyu,ZHAO Zuowei,WANG Hongjiang,GUAN Fenglin.. Expression of TNF-α and Superoxide Dismutase mRNA in Myocardium of Rats with Obstructive Jaundice. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2004, 11(6): 502-504. doi:
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