Diagnosis and Treatment on Primary Gastric Lymphoma_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

ZHANG Chao ¹ , JIANG Jun ¹ , RUAN Shengxing. ²

Department of General Surgery, Southwest Hospital, The Third Military Medical University, Chongqing 400038;

Corresponding author：

Keywords：

Gastric lymphoma; Diagnosis; Treatment

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ObjectiveTo summarize the experience of diagnosis and treatment on primary gastric lymphoma. MethodsThirtyseven patients, proved by pathology, were included in the study. ResultsAmong clinical presentation, the upper abdominal pain, intestinal bleeding, and weight loss were common. Only 4 cases were diagnosed as PGL in 33 cases with the examination of Xray barium meal, 88.5% ( 23 of 26 cases) were missdiagnosed as gastric ulcer under gastroscopy. All cases underwent operation, among them 33 had been performed a radical operation. The survival period was over 5 years in 12 of 25 patients who have been followed up. ConclusionThe multiple biopsy sampling from submucosal layer via gastroscope may improve diagnostic rate on primary gastric lymphoma. Operative removal of the tumor should be the first choice of treatment. Additional chemotherapy after the surgery increases the fiveyear survival rate.

Citation： ZHANG Chao,JIANG Jun,RUAN Shengxing.. Diagnosis and Treatment on Primary Gastric Lymphoma. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2002, 9(4): 269-271. doi: Copy

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1. Echenique EM. Current controversy in the treatment of primary gastric lymphoma [Ｊ]. Gastroenterol Hepatol, 1999; 22(10)∶533.
2. Ohashi S, Segawa K, Okamura S, et al. A clinicopathologic study of gastric mucosaassociated lymphoid tissue lymphoma [Ｊ]. Cancer, 2000; 88(10)∶ 2210.
3. Carbone PP, Kaplan HS, Musshoff K, et al. Report of the Committee on Hodgkin’s Disease Staging Classification [Ｊ]. Cancer Res, 1971; 31(11)∶ 1860.
4. Strecker P, Eck M, Greiner A, et al. Diagnostic value of stomach biopsy in comparison with surgical specimen in gastric Bcell lymphomas of the MALT type [Ｊ]. Pathologe, 1998; 19(3)∶209.
5. Jung SS, Wieman TJ, Lindberg RD. Primary gastric lymphoma and pseudolymphoma [Ｊ]. Am Surg, 1988; 54(10)∶594.
6. 胡建昆，陈志新，陈佳平，等. 原发性胃恶性淋巴瘤的诊断和外科治疗 [Ｊ]. 　中国普外基础与临床杂志，1999； 6(3)∶160.
7. Swaroop VS. Endoscopic features of gastric nonHodgkin’s lymphoma [Ｊ]. Gastrointest Endosc， 1999; 50(6)∶892.
8. Genta RM, Franceschi F. Treating biopsies to cure patients: the management of histological findings in mucosaassociated lymphoid tissue (MALT) [Ｊ]. J Clin Gastroenterol, 1999; 29(2)∶116.
9. Boot H, de Jong D, Aleman BM, et al. Comment on radiotherapy for treatment of localized gastrointestinal nonHodgkin’s lymphoma [Ｊ]. Radiother Oncol, 1998; 46(1)∶105.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Diagnosis and Treatment on Primary Gastric Lymphoma

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