Objective To explore the diagnostic and treating scheme of primary sclerotic cholangitis.
Methods 24 cases of primary sclerotic cholangitis identified by radiological and pathological examinations from 1972 to 1998 were analysed retrospectively. According to Thompson, 1 case was classified as type Ⅰ, 5 cases were type Ⅱ, 10 cases were type Ⅲ and 8 cases were type Ⅳ. The operation were as follows,resection of gallbladder plus T tube drainage in 8 cases, plus Roux-en-Y anastomosis of bile duct and jejunum in 12 cases, plus U tube stent and drainage in 4 cases.
Results The total mortality rate was 25% (6/24) in 2～18 years follow-up after operation.
Conclusion Early diagnosis and operation may resolve the drainage of bile into the jejunum. When serious lesions and worse liver functions exist, liver transplantation should be considered.
Citation：
XIA Liangfang.. PRIMARY SCLEROTIC CHOLANGITIS(REPORT OF 24 CASES). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2001, 8(2): 81-82下转100. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
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Thompson HH, Pitt HA, Tomplsins RK, et al. Primary sclerosing cholangitis: A haterogenous disease [J]. Ann Surg, 1982; 196(2)∶127.
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Lemmer ER, Bornman PC, Krige EJ, et al. Primary sclerosing cholangitis——requiem for biliary drainage operations [J]? Arch Surg,1994; 129(7)∶723.
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Ismail T, Angrisani L, Powell JE, et al. Primary aclerosing cholangitis:options, prognostic variable and outcome [J]. Surgery, 1991, 78(5):564.
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Werlin SL, Gilcklich M, Jona J, et al. Sclerosing cholangitis in childhood [J]. J Pediatr, 1980, 96(4)∶433.
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Myers RH, Cooper JH. Primary sclerosing cholangitis: Complete gross and hietologic recersal after long time steriod therapy [J]. Am J Grastroenterology, 1970; 53(5)∶527.
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傅德良，张延龄.原发性硬化性胆管炎病例的免疫异常.国外医学外科学分册，1990； 15(3)∶123.
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- 1. Thompson HH, Pitt HA, Tomplsins RK, et al. Primary sclerosing cholangitis: A haterogenous disease [J]. Ann Surg, 1982; 196(2)∶127.
- 2. Lemmer ER, Bornman PC, Krige EJ, et al. Primary sclerosing cholangitis——requiem for biliary drainage operations [J]? Arch Surg,1994; 129(7)∶723.
- 3. Ismail T, Angrisani L, Powell JE, et al. Primary aclerosing cholangitis:options, prognostic variable and outcome [J]. Surgery, 1991, 78(5):564.
- 4. Werlin SL, Gilcklich M, Jona J, et al. Sclerosing cholangitis in childhood [J]. J Pediatr, 1980, 96(4)∶433.
- 5. Myers RH, Cooper JH. Primary sclerosing cholangitis: Complete gross and hietologic recersal after long time steriod therapy [J]. Am J Grastroenterology, 1970; 53(5)∶527.
- 6. 傅德良，张延龄.原发性硬化性胆管炎病例的免疫异常.国外医学外科学分册，1990； 15(3)∶123.
- 7. 黄志强主编.现代腹部外科学 [M].第1版.长沙：湖南科技出版社，1994：482～483.
- 8. 夏亮芳.阻塞性黄疸诊断的进展[J].普外临床，1991； 6(1)∶23.
