THE EFFECTS OF AUTOLOGOUS BILE PERFUSION INTO DOG’S PANCREATIC DUCT ON THE SEVERITY OF INDUCED ACUTE PANCREATITIS_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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Department of General Surgery, Military General Hospital of Tibet, Lasha 850003;

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Acute pancreatitis; Autobile; Perfusion

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To evaluate the effects of different pressure and duration of autologous bile perfusion into dog’s pancreatic duct on the severity of induced acute pancreatitis. Thirty mongrel dogs were divided into five groups, with each group consisting of six dogs. Histological changes of pancreas were observed. Results: Histological changes of pancreas were correlated with the pressure and duration of autologous bile perfusion into pancreatic duct. It was easier to produce acute hemorrhagic necrotizing pancreatitis in the groups with a higher pressure and a longer duration of perfusion than in the groups with a lower pressure and a shorter duration. The results indicated that there was a significant effect of higher pressure and longer duration bile perfusion into pancreatic duct on the severity of induced acute pancreatitis.

Citation： Wang Maoxu,Tian Fuzhou,Zeng Rong,et al.. THE EFFECTS OF AUTOLOGOUS BILE PERFUSION INTO DOG’S PANCREATIC DUCT ON THE SEVERITY OF INDUCED ACUTE PANCREATITIS. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1999, 6(3): 134-136. doi: Copy

1.	Hansson K. Experimental and clinical studies in aetiologic role of bile reflux in acute pancreatitis. Acta Chir Scand, 1967; 375(suppl)∶53.
2.	Skinner DB. Gallstone pancreatitis. The timing of surgery. Surg, 1989; 33(6)∶350.
3.	Saitoh Y, Yomamoto M. Evaluation of severity of acute pancreatitis. Int J Pancreatol, 1991; 9(1)∶51.
4.	Boutelier P. Les pancreatitis aignes. Chirurgie, 1977; 103(12)∶856.
5.	田伏洲，黎冬暄，陈玉琼等. 胰、胆管压力变化及胆胰返流的原因分析. 中华实验外科杂志， 1997； 14(4)∶207.
6.	Farmer RC, Tweedie J, Maslin S, et al. Effects of bile salts on permeability and morphology of main pancreatic duct in cats. Dig Dis Sci, 1984; 290(11)∶740.
7.	Hirano T, Manabe T. A possible mechanism for gallstone pancreatitis: repeated shortterm pancreaticobiliary duct obstruction with exocrine stimulation in rats (43534). Pro Soc Exp Brol Med, 1993; 202(4)∶246.

1. Hansson K. Experimental and clinical studies in aetiologic role of bile reflux in acute pancreatitis. Acta Chir Scand, 1967; 375(suppl)∶53.
2. Skinner DB. Gallstone pancreatitis. The timing of surgery. Surg, 1989; 33(6)∶350.
3. Saitoh Y, Yomamoto M. Evaluation of severity of acute pancreatitis. Int J Pancreatol, 1991; 9(1)∶51.
4. Boutelier P. Les pancreatitis aignes. Chirurgie, 1977; 103(12)∶856.
5. 田伏洲，黎冬暄，陈玉琼等. 胰、胆管压力变化及胆胰返流的原因分析. 中华实验外科杂志， 1997； 14(4)∶207.
6. Farmer RC, Tweedie J, Maslin S, et al. Effects of bile salts on permeability and morphology of main pancreatic duct in cats. Dig Dis Sci, 1984; 290(11)∶740.
7. Hirano T, Manabe T. A possible mechanism for gallstone pancreatitis: repeated shortterm pancreaticobiliary duct obstruction with exocrine stimulation in rats (43534). Pro Soc Exp Brol Med, 1993; 202(4)∶246.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

THE EFFECTS OF AUTOLOGOUS BILE PERFUSION INTO DOG’S PANCREATIC DUCT ON THE SEVERITY OF INDUCED ACUTE PANCREATITIS

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