Liver transplantation in hamster-to-rat is a good model for the research in xenograft, but it is difficult to be performed. In order to simplify its procedures, 38 cases of liver transplantation in hamster-to-rat were performed with several technique improvments on the basis of orthotopic liver transplantation in rats. In the light of hamster’s anatomy, three cuffs anastomosis method was used. Because of its high stability and high survival rate, the model can be used widely as the research for liver xenograft.
Citation：
Tan Jingwang,Zhang Shaogeng,Qian Guangxiang,et al.. THE MODIFIED FOR ORTHOTOPIC LIVER TRANSPLANTATION MODEL IN HAMSTER-TO-RAT. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1999, 6(4): 201-203. doi:
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- 1. Calne RY. The xenograft. Netherlands: Elsevier Science Publishers BV, 1990∶3-7.
- 2. Harihara Y, Sanjo R, Idesuki Y, et al. A modified cuff technique for superhepatic vena cava anastomosis. Transplantation, 1992; 53(4)∶707.
- 3. Kamada N, Calne RY. Orthotopic liver transplantation in the rat. Transplantation, 1977; 28(1)∶47.
- 4. 严以群， 杨甲酶， 王轩等. 大鼠减体积性肝移植模型的初步研究. 中华器官移植杂志， 1996； 4(2)∶55.
- 5. 曾祺华， 孙君泓， 吴孟超. 三袖套法大鼠原位肝移植术. 中华器官移植杂志， 1989； 10(2)∶159.
