• Department of Hepatobiliary Pancrese Surgery,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029;
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Aippuric acid test(HAT) and hepatic energy metabolism and mitochondrial oxidative phosphorylation activity in rabbit with acute obstractive jaunidce was studied.The result showed that the HAT values were decreased from 98.4±32.0mg/h to 32.7±17.6mg/h(P lt;0.001),energy charge(EC) decreased from 0.81±0.01 to 0.72±0.02(P lt;0.001),and phosphorylation rate(PR)decreased from 62.1V5.1 to 38.3V2.4(P lt;0.001).Correlation coefficients between HAT and EC was 0.786,(P lt;0.001).This result suggests that HAT can be used as an indicator of hepatic energy metabolism status in acute obstructive jaundice.

Citation: Zhang Feng,Yu Xueming,Wang Xuehao,et al.. EXPERIMENTAL STUDY OF HIPPURIC ACID TEST AS AN INDICATOR OF HEPATIC ENERGY METABOLISM IN RABBIT WITH ACUTE OBSTRUCTIVE JAUNDICE. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1997, 4(2): 63-67. doi: Copy

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