Ｔｏ ｉｎｖｅｓｔｉｇａｔｅ ｔｈｅ ｃｈａｒａｃｔｅｒｉｓｔｉｃ ｏｆ ａｎｔｉｂｏｄｉｅｓ ｔｈａｔ ｉｎｄｕｃｅ ｔｈｅ ｒｅｊｅｃｔｉｏｎ ｏｆ ｘｅｎｏｇｒａｆｔｉｎｇ，ＳＤ ｒａｔｓ ｗｅｒｅ ｉｍｍｕｎｉｚｅｄ ｗｉｔｈ ＮＩＨ ｍｉｃｅ ｓｐｌｅｅｎ ｔｏ ｐｒｅｐａｒｅ ｒａｔ ａｎｔｉｍｏｕｓｅ ａｎｔｉｓｅｒａｓ． Ｔｈｅ ａｎｔｉｂｏｄｉｅｓ ｗｅｒｅ ｐｕｒｉｆｉｅｄ ｂｙ ｃａｐｒｙｌｉｃ ａｃｉｄ ｐｒｅｃｉｐｉｔａｔｉｏｎ ａｎｄ ｈｙｄｒｏｘｙ ｌａｐａｔｉｔｅ（ＨＰＴ）ｃｈｒｏｍａｔｏｇｒａｐｈｙ．Ｔｈｅ ｒｅｓｕｌｔｓ ｓｈｏｗｅｄ ｔｈａｔ ｔｈｅ ｔｉｔｌｅ ｏｆ ｒａｔ ａｎｔｉｍｏｕｓｅ ａｎｔｉｓｅｒａ ｗａｓ １∶６４０，ａｎｄ ｔｈｅ ａｎｔｉｂｏｄｉｅｓ ｐｕｒｉｆｉｅｄ ｂｙ ｃａｐｒｙｌｉｃ ａｃｉｄＨＰＴ ｈａｄ ｒｅｌｉａｂｌｅ ｐｕｒｉｔｙ ａｎｄ ｇｏｏｄ ｉｍｍｕｎｏｃｏｍｐｅｔｅｎｃｅ．Ｔｈｉｓ ｍｅｔｈｏｄ ｃｏｕｌｅ ｂｅ ｕｓｅｄ ｉｎ ｐｒｅｐａｒａｔｉｏｎ ａｎｄ ｒｅｓｅａｒｃｈ ｏｆ ｍａｊｏｒ ｈｉｓｔｏｃｏｍｐａｔｉｂｉｌｉｔｙ ａｎｔｉｂｏｄｉｅｓ．
Citation： 兰平,王吉甫. ＰＲＥＰＡＲＡＴＩＯＮ ＯＦ ＲＡＴ ＡＮＴＩＢＯＤＩＥＳ ＡＧＡＩＮＳＴ ＭＯＵＳＥ ＭＡＪＯＲ ＨＩＳＴＯＣＯＭＰＡＴＩＢＩＬＩＴＹ ＡＮＴＩＧＥＮ. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1997, 4(3): 129-131. doi: Copy
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