Radioimmunoassay was performed to measure carcinoembryonic antigen (CEA) levels in gastric juice before and after operation in 51 gastric cancer patients (group Ⅰ)， 33 patients with gastric benign lesion (group Ⅱ) and 8 patients with malignant lesion in digestive system other than gastric cancer (group Ⅲ). The results showed that preoperative CEA levels of in group Ⅰ were the highest among three groups (Ｐ＜0.01), but no statistic difference was noted in group Ⅱ and group Ⅲ. In group Ⅰ and group Ⅱ, postoperative CEA levels were higer than the preoperative levels. The authors believe that preoperative CEA measurement of gstric juice is an accessory method in diagnosing gastric cancer, nevertheless, there is no diagnostic significence of postoperative measurement in patient undergone partial gastrectomy.
Citation：
Liang Tingbo,Yu Jiren,Zheng Shusen,et al.. SIGNIFICANCE OF PRE-AND POSTOPERATIVE CARCINOEMBRYONIC ANTIGEN MEASUREMENT OF GASTRIC JUICE IN GASTRIC CANCER PATIENT. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1995, 2(2): 79-81. doi:
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- 1. Gold P, Freedman SO. Demonstration of tumor specific antigen in human colonic carcinoma by immunological tolerance and absorption technique. Exp Med, 1965;121(3):439.
- 2. Go VLW, Ammon HV, Holtermuller KH, et al. Quantification of carcioembryonic antigen like actiites in normal human gastrointestinal secretion. Cancer, 1975;36:2438.
- 3. Harrison JD. CEA and CA19-9 in gastric juice and serum an aid in the diagnosis of gastric carcinoma. Eur J Surg Onhcol, 1988;15(3):253.
- 4. 孙龙安，颜万顺，邓小虎等.胃癌患者血清CEA和β-2微球蛋白联合测定的临床价值.中华核医学杂志，1988；(2)：86.
- 5. 章峰，缪庆才，郭伯华.胃液癌胚抗原含量对胃癌的诊断意义.中国肿瘤临床，1988；(2)：104.
- 6. Tatsuta M. Value of gastric juice carcinoembryonic antigen in identifying high-risk patients for gastric cancer. Oncology, 1988;45(1):30.
- 7. 周末工，张嘉庆.癌胚抗原的研究进展.普外临床，1988；(1)：56.
