• Department of Respiratory Medicine,The First Affliated Hospital of Nanjing Medical University.Nanjing,Jiangsu,210029,ChinaCorresponding author:LIU Jie,E-mail:liujie@wx5h.com;
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Objective  To investigate the changes of stem cell factor(SCF) level in serum of asthma patients before and after acute exacerbation.Methods  The serum SCF was detected in 30 asthma patients respectively in the onset period and catabasis by ELISA.The SCF levels were also determined in 20 normal subjects as control.Results  the content of serum SCF of the asthma patients during the acute attack was increased significantly than normal subjects [(156.8±82.6)pmol/L vs (61.5±15.4)pmol/L,P lt;0.001],and decreased significantly in remission [(66.2±15.8)pmol/L,P lt;0.001].Conclusions  SCF may participate in the pathogenesis of asthma.

Citation: LIU Jie,YIN Kaisheng,XUE Yifeng,HU Zhigang. The clinical significance of stem cell factor in serum of asthma patients. Chinese Journal of Respiratory and Critical Care Medicine, 2007, 6(3): 191-193. doi: Copy

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