WU Minsheng , ZHAO Xiaoqin , CHEN Qiang
  • Intensive Care Unit, First Affiliated Hospital, Guangxi Medical University. Nanning, Guangxi,530021, ChinaCorresponding Author: WU Min-sheng, E-mail: bnn5839160@ sohu. com;
Acute kidney injury; Multiple organ dysfunction syndrome; Acute physiology andchronic health evaluation
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Objective  To compare the clinical value of Acute Physiology and Chronic Health Evaluation ( APACHE) Ⅱ / Ⅲ scoring system in predicting the prognosis of patients complicated with acute kidney injury ( AKI) and multiple organ dysfunction syndrome ( MODS) in ICU. Methods  318 patients with AKI and MODS treated with continuous blood purification in ICU fromJanuary 2004 to June 2010, were evaluated with APACHE Ⅱ and APACHEⅢ and analyzed retrospectively. The area under the receiver
operating characteristic curve ( AUC) and the Lemeshow-Hosmer goodness-of-fit of APACHEⅡ and Ⅲ were assessed. Results  Mean scores and predicted hospital mortality of APACHEⅡ and Ⅲ were all significantly lower in the survival group than those in the non-survival group ( P  lt; 0. 01) . The AUC were 0. 782 for APACHEⅡ, and 0. 755 for APACHEⅢ, with Youden’s indexes of 46. 4% and 36. 7% , respectively. Hosmer-Lemeshow test showed the calibration of the two systems was reasonable. Conclusion  APACHEⅡ and Ⅲ are both good for predicting the severity and prognosis of patients complicated with AKI and MODS in ICU but APACHEⅡ is superior in clinical practice.

Citation： WU Minsheng,ZHAO Xiaoqin,CHEN Qiang. Comparison of APACHEⅡ and Ⅲ Scoring System in Predicting the Prognosis of Patients with Acute Kidney Injury and Multiple Organ Dysfunction Syndrome in ICU. Chinese Journal of Respiratory and Critical Care Medicine, 2011, 10(2): 154-157. doi: Copy

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