Objective To study the effect of myofibroblast on the development of pathological scar. Methods From 1998 to 2000, 14 cases of keloid(k), 13 cases of hypertrophic scar(HS), and 7 cases of scar were studied through immunohistochemistry and electronical microscope. Results Myofibroblasts were often observed in the hypertrophic HS by electronical microscope, but no myofibroblast was observed in the K and NS. αSMactin was expressed in fibroblast of HS, but was not expressed in K and NS. Conclusion Myofibroblast may play a role in the development of hypertrophic scar. The difference between the absence of myofibroblast in keloid and the invasion of keloid deserves further study.
Citation: LIU Yong,CEN Ying,TANG Ying,et al.. THE ROLE OF MYOFIBROBLAST IN THE DEVELOPMENT OF PATHOLOGICAL SCAR. Chinese Journal of Reparative and Reconstructive Surgery, 2005, 19(1): 39-41. doi: Copy
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