OBJECTIVE: To investigate the selection and manufacture of ideal extracellular matrix materials in bone tissue engineering. METHODS: The recent literatures about biodegradable polymers served as culture scaffolds of osteoblasts were widely reviewed, the advantages and disadvantages of biodegradable synthetic polymers and natural polymers were analysed. RESULTS: The ideal extracellular matrix material in bone tissue engineering should be made up of inorganic materials, synthetic polymers and natural polymers, which possesses morphological structure of three-dimensional foam with self-mediated drug slow delivery system of bone growth factors. CONCLUSION: The design and manufacture of combined extracellular matrix materials in bone tissue engineering is a very important and urgent challenge.
Citation： ZHENG Lei,WANG Qian,PEI Guo xian.. DEVELOPMENT OF BIODEGRADABLE POLYMER SCAFFOLDS FOR BONE TISSUE ENGINEERING. Chinese Journal of Reparative and Reconstructive Surgery, 2000, 14(3): 175-189. doi: Copy
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