目的：研究影响机械通气患者BIS值的相关因素。方法：42例机械通气患者，BIS模块连续监测镇静深度48小时，记录患者镇静前后、每隔16小时的呼吸循环指标，BIS值、SAS评分，建立混合线形统计模型，评价BIS监测的影响因素。结果：患者的血压、心率、呼吸频率、PaO2、SPO2 、FiO2等均对BIS值无影响，仅有PaCO2和SAS评分与BIS相关(P＜0.05)。结论：BIS模块监测机械通气患者镇静深度，BIS值的变化与患者PaCO2及SAS评分有关。
Citation：
LI Xiaojin,ZHANG Chuan,ZHENG Bixia,et al. The Research of Related Factors in Affecting the Bispectral Index Monitoring for the Depth of Sedation of Ventilated Patients. West China Medical Journal, 2009, 24(2): 362-363. doi:
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- 1. Brocas，E，Dupont，H，Paugam Burtz C.Bispectral index variations during tracheal suction in mechanically ventilated critically ill patients：effect of an alfentanil bolus[J].Intensive Care Med，2002，28(2)：211-213..
- 2. Ball J.How useful is the bispectral index in the management of ICU patients?[J]Minerva Anestesiol，2002，68(4)：248-251..
- 3. Simmons L E，Riker R R，Prato B S，et al.Assessing sedation during intensive care unit mechanical ventilation with the Bispectral Index and the SedationAgitation Scale[J].Crit Care Med，1999，27(8)：1499-1504..
- 4. Mondello E，Siliotti R，Noto G，et al.Bispectral Index in ICU：correlation with Ramsay Score on assessment of sedation level[J].J Clin Monit Comput，2002，17(5)：271-277..
- 5. Riker R R，Fraser G L，Simmons L E，et al.Validating the SedationAgitation Scale with the Bispectral Index and Visual Analog Scale in adult ICU patients after cardiac surgery[J].Intensive Care Med，2001，27(5)：853-858..
- 6. 张川，李孝锦，李晓玉，等.BIS监测对诊断机械通气患者镇静深度的价值[J].华西医学，2008，23，(1)：41-42..
- 7. Medicis JJ，Hu A，Lopez C，et al.Comparsion of standard sedation assessment to bispectral analysis in patients who are on neuromuscular blockers：A pilot study[C].ASHP Midyear Clinical Meeting(ASHP Midyear Clinical Meeting)，2002，37(DEC)：P-347R..
