Clinical Investigation of Severe Acute Pancreatitis Complicated with Infection_West China Medical Journal

Authors：

YANGXiaonan, ZHAO Long, JIN Tao, et al.

1Department of Integrated Traditional Chinese and Western Medicine;2 Department of Three of General Surgery, West China Hospital, Sichuan University, Chengdu,Sichuan 610041,China;

Corresponding author：

Keywords：

重症急性胰腺炎; 感染; 多脏器功能衰竭

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摘要:目的:探讨重症急性胰腺炎(SAP)继发感染的临床特点。方法:将我院20039~20053收治的SAP140例,按是否感染,分成感染组和对照组,对比分析其临床资料。结果:感染组病死率高于对照组(P=0023);感染组入院初期,Ranson评分、CT评分、APACHE Ⅱ评分、血糖、ARDS和肠麻痹发生率、感染前手术率及呼吸机辅助呼吸率高于对照组(P lt;005);以G感染胰腺、胰周围及肺部为主;肺部感染时间为107±25d,胰腺或胰周为176±29d。结论:急性期全身反应轻重及胰腺坏死程度是SAP继发感染的基础;临床有创治疗措施是促进因素。

Citation： YANG Xiaonan,ZHAO Long,JIN Tao,et al.. Clinical Investigation of Severe Acute Pancreatitis Complicated with Infection. West China Medical Journal, 2009, 24(5): 1137-1139. doi: Copy

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1. 贾林,袁世珍.急性胰腺炎:临床诊治新观点(世界胃肠病大会2005)[J].胰腺病学,2005,5(4):240.
2. J TOOULI, M BROOKESMITH, C BASSI, et al. Guidelines for the management of acute pancreatitis[J]. J Gastroenter Hepat,2002,17(suppl):S15S39.
3. 刘续宝,蒋俊明,黄宗文,等.中西医结合治疗重症急性胰腺炎的临床研究(附1367例报告)[J].四川大学学报(医学版),2004,35(2):204208.
4. PER LEVEAR, WANG X D, VASILE, et al. Alterations intestinal motiliy and microflora in experimental acute pancreatitis[J]. Int J Pancreatology,1996,20:119.
5. ARMENGOLCARRASCO M, OLLER B, ESCUDERO L E, et al. Specific prognosticfactors for secondary pancreatic infection in severe acute pancreatitis[J]. Dig Surg,1999,16 (2):1255.
6. NICHOLS, MATTHEW T, RUSS, et al. Pancreatic Imaging: Current and Emerging Technologies[J]. Pancreas, 2006, 33(3): 211220.

West China Medical Journal

Clinical Investigation of Severe Acute Pancreatitis Complicated with Infection

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