【摘要】目的探讨肝血管平滑肌脂肪瘤的临床病理特点、诊断及鉴别诊断。
方法对3例肝血管平滑肌脂肪瘤患者有关病理检查结果进行回顾性分析。
结果肿瘤位于肝右叶2例,肝左叶1例。肿瘤直径为2~10 cm,平均6.2 cm。3例肿瘤内均见平滑肌、脂肪、畸形厚壁血管,但未见髓外造血灶。对黑色素瘤(HMB45)、结合蛋白(desmin)及肌动蛋白(actin)检查均呈阳性反应。术后随访6~36个月,未见肿瘤复发。
结论肝血管平滑肌脂肪瘤由3种成分组成,病理形态变化多样,必须与多种肝肿瘤相鉴别。平滑肌细胞HMB45表达呈强阳性反应是诊断肝血管平滑肌脂肪瘤较可靠的依据。
Citation:
马云海,李健生 陆桂君. Clinicopathological Analysis of Hepatic Angiomyolipoma. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2005, 12(2): 179-180. doi:
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Tsui WM, Colombari R, Portmann BC, et al. Hepatic angiomyolipoma: a clinicopathologic study of 30 cases and delineation of unusual morphologic variants [J]. Am J Surg Pathol, 1999; 23(1)34.
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Hoffman AL,Emre S,Verham RP,et al.Hepatic angiomyolipoma:two cases reports of caudatebased lesions and review of the literature [J]. Liver Transpl Surg, 1997; 3(1)46.
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张丽萍,吕翔,黄志勇,等. 肝血管平滑肌脂肪瘤3例临床病理分析 [J]. 诊断病理学杂志, 2001; 48(2)82.
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Guidi G,Catalano O,Rotondo A. Spontantous ruptllre of a hepatic angiomyolipoma;CT findings and Literature review [J]. Eur Radiol, 1997; 7(2)3335.
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- 1. Tsui WM, Colombari R, Portmann BC, et al. Hepatic angiomyolipoma: a clinicopathologic study of 30 cases and delineation of unusual morphologic variants [J]. Am J Surg Pathol, 1999; 23(1)34.
- 2. Hoffman AL,Emre S,Verham RP,et al.Hepatic angiomyolipoma:two cases reports of caudatebased lesions and review of the literature [J]. Liver Transpl Surg, 1997; 3(1)46.
- 3. 张丽萍,吕翔,黄志勇,等. 肝血管平滑肌脂肪瘤3例临床病理分析 [J]. 诊断病理学杂志, 2001; 48(2)82.
- 4. Guidi G,Catalano O,Rotondo A. Spontantous ruptllre of a hepatic angiomyolipoma;CT findings and Literature review [J]. Eur Radiol, 1997; 7(2)3335.