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Animal Experiment Study for The Efficacy of Xiaochengqi-Mixture on Promoting Healing of Colonic Stoma

ObjectiveTo evaluate the efficacy of XiaochengqiMixture (XM) on promoting healing of colonic stoma. MethodsForty Wistar rats were divided into two groups randomly after colonectomy: experimental group (n=20) and control group (n=20). In early postoperatively stage rats were given gastric administration of XM in the experimental group and pure water in the control group. On day 3, 7, and 14 after establishment of animal models, laparotomy was performed in two groups of rats, respectively. Anastomotic stoma and surrounding tissues were harvested to detect the context of hydroxyproline and collagen fiber proportion by Masson dying. ResultsOn day 3 after establishment of animal models, hyperplastic collagen with small fiber was observed while no fasciculus was found. Hydroxyproline context and collagen fiber proportion of rats were higher in experimental group than those in control group (Plt;0.05). On day 7 after operation, many fasciculuses were found in two groups of rats, hydroxyproline context and collagen fiber proportion of rats were higher in experimental group than those in control group (Plt;0.01). On day 14 after operation, fasciculuses became bigger and more regular in arrangement, but there was no significant difference between the two groups (Pgt;0.05). ConclusionXM is capable of promoting healing of colonic stoma and might prevent the occurrence of anastomotic fistula.

EXPERIMENTAL STUDY OF WHOLE-LAYER AND PART-LAYER ANASTOMOSIS OF SMALL ARTERY

Using 70 SD white rats, diveded in two groups at random, after the common carotid artery wa(?) exposed, anastomosis of the artery was done by whole-layer suture and suture without including the endothelial layer, respectively. The rate of patency of both groups immediately after operation was 100 percent, where as in late stage, 94 percent and 97 percent, respectively. From the histologic exam ination, it was found that in the group of whole-layer suture, the time required to cover the sutureline with endothelium was delayed and there was rupture of the clastic fibers.

The Experience of 1 600 Cases for Digestive Tract SingleLayer Anastomosis

目的对单层吻合在消化道手术中临床应用的安全性和实用性进行评价。方法对该院1 600例消化道单层吻合术的临床资料进行回顾性分析，并结合国内外文献进行讨论。结果全组1 600例消化道单层吻合手术均顺利完成，发生吻合口漏25例（1.56%），吻合口狭窄3例（0.19%），无一例发生吻合口大出血。结论消化道单层吻合不会增加吻合口漏的发生率，并能减少吻合口狭窄、梗阻和出血，是安全、实用且有效的吻合方法。

坡面切除、胃肠道单层宽边等距吻合术(附1 207例报告)

Hemorrhoidectomy and Circumferential Stapled Mucosectomy for Prolapse and Hemorrhoids (Report of 30 Cases)

目的探讨痔切除吻合器痔上粘膜环切术（PPH）的临床应用价值。方法采用33 mm痔切除吻合器痔上粘膜切除术对严重脱垂性痔30例进行治疗。结果全组病例平均手术时间10分钟，术后住院时间1～3天，脱出痔块均回缩，切除直肠粘膜完整率达98%，术后90%的患者无肛门疼痛，随访3个月，28例满意，2例基本满意。结论采用痔切除吻合器痔上粘膜环切术治疗严重脱垂性痔是一种新技术，其手术操作简单，具有安全、有效、手术时间短、术后疼痛轻、恢复快等特点，有望替代传统的治疗方法。

Randomized Control Study on Seromuscular Layer Anastomosis and Two-Layer Anastomosis in Small Intestinal Suture

Objective To evaluate the safety and effect of seromuscular layer anastomosis in small intestinal suture. Methods Forty patients with hepatobiliary and pancreatic diseases undergoing biliojejunostomy or cystojejunostomy were randomly divided into seromuscular layer anastomosis group (n=20) and two-layer anastomosis group (n=20) before operation， which received Roux-en-Y end-to-side jejunal seromuscular layer anastomosis and two-layer anastomosis, respectively. Intestinal anastomotic complications and other indexes such as anus venting time were recorded in each group. Results Neither group had intestinal anastomotic complications such as leakage, stricture, obstruction and hemorrhage. Time of venting to normal were (3.6±0.9) d and (3.6±0.8) d in seromuscular layer and two-layer anastomosis group respectively, there was no significant difference between them (Pgt;0.05). Conclusion Seromuscular layer anastomosis is a safe and effective method of small intestinal anastomsis.

EXPERIMENTAL AND CLINICAL STUDY OF IMPROVED TECHNIQUES OF 0.3～0.5MM MI CROVASCULAR ANASTOMOSIS

Several techniques were used to improve 0.3～0.5 mm microvascular anastomosis. These included (1) non-isolation of adventitia, (2) modified two—point anastomosis, (3) clamping only the inflow in veins anastomosis, (4) atraumatic measurement of vascular patency, (5) post operative stimulation by electromagnetic fields, which accelerated the healing of the vessels. The chance of patency following anastomosis in experimental group was significantly much greater than that in the control one (plt;0.001). We have have also used these techniques in 11 patients with fingers replantion or smaller lymphatic anastomosis. All of the operations were successful.

FREE JEJUNAL GRAFTS FOR RECONSTR--UCTION OF PHARYNX AND CERVICALESOPHAGUS

Reports 3 cases of transplantation ofmicrovaseular jejunal segments to reconstracthypopharynx and cervical esophagus. Threewere survived. The major advantages of thistechnique include the fat that it is a one staseprocedure, thereby allowing early rehabilita -tion , and that the complication rate is low.

The Safety and Efficacy of Roux-en-Y Reconstruction with Isolated Pancreaticojejunos-tomy after Pancreaticoduodenectomy: a Meta-Analysis

ObjectiveTo evaluate the safety and efficacy of Roux-en-Y reconstruction with isolated pancreatico-jejunostomy after pancreaticoduodenectomy. MethodsSystematically literature search was performed through PubMed, EMBASE, Cochrane Library, Wanfang, VIP, and CNKI from the earliest to November 30, 2015. Randomized clinical trials (RCTs) and controlled clinical trials (CCTs) comparing outcomes of Roux-en-Y reconstruction with isolated pancrea-ticojejunostomy and conventional pancreaticojejunostomy were searched. The data were applied meta-analysis by RevMan 5.3. ResultsSeven trials were involved, two RCTs including 367 patients and five CCTs including 431 patients. Meta-analysis result showed that there was no statistic significant difference in pancreas fistula between Roux-en-Y reconstruction with isolated pancreaticojejunostomy and conventional pancreaticojejunostomy. ConclusionRoux-en-Y reconstruction with isolated pancreaticojejunostomy after pancreaticoduodenectomy is not superior to conventional pancreaticojejunostomy regarding pancreatic fistula rate or other relevant outcomes.

经皮经肝胆道镜碎石取石术治疗胆肠吻合术后肝胆管结石病

目的探讨经皮经肝胆道镜碎石取石术（PTCSL）必要时联合球囊扩张治疗胆肠吻合术后肝胆管结石病的可行性及安全性。方法重庆医科大学附属第二医院 2015 年 12 月至 2020 年 12 月期间共有 54 例胆肠吻合术后肝胆管结石病患者接受 PTCSL 必要时联合球囊扩张治疗（符合纳入标准）。回顾性收集患者的一般资料、手术情况、术后情况以及术后随访资料。结果54 例患者中有 52 例（96.3%）行 PTCSL 治疗成功，2 例因为胆肠吻合口完全闭塞而失败。术中出血量的中位数为 55 mL（15～520 mL）；取净结石 48 例（88.9%），结石残留 6 例（11.1%）。术后并发症发生率为 27.8%（15/54），无围手术期死亡患者。取净结石的 48 例患者获随访，中位随访时间 33 个月（2～60 个月），有 10 例结石复发，复发率为 20.8%（10/48）。结论PTCSL 必要时联合球囊扩张治疗胆肠吻合术后肝胆管结石病具有良好的安全性和可行性，但是术后需要注意预防结石复发。