ObjectiveTo investigate the potential effect of hyperopia status on subfoveal choroidal thickness (SFCT) in silicone oil (SO)-filled eyes.MethodsThis self-comparative study was conducted in Department of Ophthalmology, Central Theater Command General Hospital. The 50 patients (100 eyes) were collected with unilateral macula-on rhegmatogenous retinal detachment from January 2019 to July 2019, who successfully underwent pars plana vitrectomy (PPV) and SO tamponade. Retinal reattachment was observed after surgery in all patients. One month after PPV, the affected eye was wore soft, contact lenses for 24 hours to correct refractive error (RE), depending on its optometry value. The SFCT of the affected eyes was measured using OCT before and after lenses wear. The fellow eyes also received OCT examination at the same time. T test was used to compare SFCT between SO-filled eyes and fellow eyes.ResultsThe mean RE of the SO-filled eyes was +6.38±1.12 D. The mean SFCT of SO-filled eyes (247.12±17.63 μm) was significantly thinner than that of the fellow eyes (276.32.55±17.63 μm) (P＜0.001). The SFCT of the SO-filled eyes was significantly thinner than fellow eyes, and the difference was statistically significant (t=－3.95, P＜0.001). After lenses wear, the mean SFCT of the SO-filled eyes increased to 276.32±24.86 μm. Compared with before lenses wear, the difference was statistically significant (t=－4.30, P＜0.001). Compared with the fellow eye, the difference was not statistically significant (t=0.05, P＞0.05).ConclusionSFCT reduction in the SO-filled eyes may be due to the hyperopia status caused by SO, which can be reserved by RE correction.
Objective To investigate the characteristic of the multifocal visual evoked potentials(MVEP)and the visual function across the visual field in anisometropic amblyopes and isometropic amblyopes. Methods MVEP from 32 anisometropic amblyopic eyes and 31 control eyes were tested. Results In anisometropic amblyopic eyes,the latencies of MVEP were significantly prolonged．The amplitudes of MVEP were significantly attenuated in the central region of the visual field,and these phenomena gradually reduced with the increase of the eccentricity． Conclusion The visual function of anisometropic amblyopic eyes is reduced more significantly in the central region than in the peripheral region of the visual field. (Chin J Ocul Fundus Dis,20000,16:27-29)
ObjectiveTo observe the changes in refractive status of eyes with idiopathic macular hole (IMH) after vitrectomy and phacoemulsification and IOL implantation (combined surgery).MethodsA retrospective clinical study. From January 2016 to June 2019, 51patients (56 eyes) of IMH who underwent combined surgery at the Tianjin Medical University Eye Hospital. were included in the study. Among them, there were 17 males and 34 females with the average age of 66.79±4.33 years. All the affected eyes underwent BCVA, retinoscopy and axial length (AL) measurement. The IOL power was calculated according to the SRK-T formula and the refractive power (predicted value) was predicted. The average BCVA of the affected eye was 0.20±0.13. The average anterior chamber depth was 2.89±0.28 mm. The average △corneal astigmatism was 0.73±0.43 D, the average AL was 22.92±0.70 mm, the average predicted refractive power was 0.10±0.66 D. All the affected eyes underwent standard transciliary flat part three-channel 25G combined surgery. Six months after the operation, the actual value (actual value) of the diopter after the operation was measured with the same equipment and method before the operation. Paired t test was used to compare the difference between the predicted value and the actual value.ResultsSix months after the operation, the actual value of the refractive power was -0.19±0.64 D. Compared with the pre-operative refractive power, the difference was not statistically significant (t=1.665, P=0.102). The difference between the actual value and the predicted value was －0.33±0.81 D.ConclusionsThe refractive status of the IMH eye undergoes myopia drift after combined surgery. The preoperative IOL power budget can be appropriately reserved for +0.3 D hyperopia.
Purpose To investigate the influence of ametropia on stereopsis and its mechanism by using the disparity evoked potential testing. Methods A new set of static random dot stereograms was utilized as a stimulation to elicit the disparity evoked potentials in 21 ametropes and 40 stereo normal subjects. Rezults The P250 wave,which was related to stereoscopic stimulation in ametropes,was recorded in both the ametropes and emetropic stereo normal persons in this series,and the characteristic changes of P250 wave with increasing visual disparity in ametropes were similar to those in normal subjects.The differences of mean amplitudes and latencies of P250 waves between myopes and hyperopes were not significant. Conclusion Ametropia in full correction dose not significanly affect the function of stereopsis. (Chin J Ocul Fundus Dis,1998,14:225-227)
Objective To verify the changes of optics and refraction of the eyes after retinal detachment surgery with the tamponade of silicone oil in vitreous cavity. Methods The optical calculation was taken as the following by using the parameter of Gullstrand model eye:（1）The refraction of silicone filled eye in non-accommodative status;（2）The refraction of silicone filled eye in non-accommodative status;（3）The aniseikonia analysis when one eye filled with the silicone oil;（4）The IOL power re-calculation． Results （1） Compa red with the normal eye,the eye filled with silicone oil is moved toward high hyperopia of +9．19 D;（2）When corrected,the accommodation amplitude reduced 1.42 D induced by filling silicone oil. Conclusion When eye filled with silicone oil,the change of refractive power tends to be highly hyperopic,the amplitude of accommodation decreased,and the regular IOL power calculation formula is no longer available. (Chin J Ocul Fundus Dis，2000，16：139-212)
Cataract combined with retinopathy can seriously affect the vision of patients. Vitrectomy combined with one-stage implantation of multi-focal intraocular lens (MIOL) has been paid more and more attention. The application of MIOL shows potential in improving the visual quality of patients, but its effect is affected by many factors, and refractive drift is a key problem to be solved. At present, the research mainly focuses on cataract patients with high myopia, and further research on other types of retinopathy is needed. In the future, multi-center, large-sample, long-term clinical studies and interdisciplinary cooperation are needed to optimize surgical and management programs to enhance the application effect of MIOL in the treatment of retinopathy and improve the quality of life of patients.
Objective To observe visual field outcome and refractive status of patients with retinopathy of prematurity (ROP) treated by laser photocoagulation. Method The data of 39 ROP patients (73 eyes) who received laser photocoagulation were retrospectively analyzed and compared with 13 normal control subjects (25 eyes) whose age and sex were matched with ROP group. There were 24 males (45 eyes) and 15 females (28 eyes) in ROP group, with an average age of (7.0±1.28) years. The first laser treatment was carried out at postnatal age (PA) of (38.74±3.82) weeks, the birth weight (BW) of (1402.33±369.61) g and the number of laser burns was (517.86±277.40). The control group included 7 females (13 eyes) and 6 males (12 eyes), with an average age of (7.17±0.96) years. The age (t=0.691) and gender (χ2=1.425) were comparable between the two groups (P=0.491, 0.233). The data of patients and controls were retrospectively analyzed including best corrected visual acuity, refractive examination, automated perimetry test. The differences of the mean deviation (MD) of visual field and the spherical equivalent (SE) between these two groups were comparatively observed. ROP patients were divided into no VF loss group (MD≤2 dB) and VF loss group (MD＞2 dB), mild VF loss group (MD≤6 dB) and moderate VF loss group (MD＞6 dB) according to the results of automated perimetry test, the differences of gestational age (GA), PA, BW, number of laser burns and SE between these groups were comparatively observed. Results The MD in ROP group and control group were 4.87±5.12 dB and 1.27±3.34 dB, respectively; the difference between the two groups was statistically significant (t=–4.01,P＜0.001). The subgroup analysis showed that BW, number of laser burns, and SE were significantly different between no VF loss group and VF loss group (t=2.074, –1.996, –2.162;P=0.042, 0.026, 0.034); while the GA was not significantly different between these two groups (t=1.973,P=0.052). The difference of PA was not statistical significant different between mild VF loss group and moderate VF loss group (t=2.03,P=0.051) and SE was significantly different between the above two groups (t=3.283,P=0.002). For refractive outcomes, the BW and ROP stage correlated with SE significantly (r=–0.304, –0.387;P=0.015, 0.002). The mean BCVA in ROP group was 0.84±0.23, and 59 eyes (91.2%) with BCVA better than 0.5. Conclusion Laser treatment for ROP tends to have less effect on long term refractive status and VF loss, with good visual outcome.
Objective To investigate the refractive changes of ocular measurable factors due to scleral buckling surgery. Methods A total of 86 eyes of successful rhegmatogenous retinal detachment with a higher encircling scleral buckle underwent A-scan and keratometer examination before surgery as well as l week,4 and 12 weeks after surgery.The refractive factors included the depth of anterior chamber,thickness of lens,axial length of eye,corneal curvature and refraction of eye were detected pre- and post-operatively. Results Compared with preoperation,the depth of anterior chamber was decreased significantly at the lst,4th and 12th postoperative week(P＜0.05),while no significant change of the axial length of eye was observed.The thickness of lens was increased significantly and the refractive error was myopic shifted at the lst and 4th week after operation(P＜0.05),but no significant change was observed at the 12th postoperative week.Statistically significant difference was also observed in corneal curvature of central axis in the local bucklele;1 quadrant with encircling group between preoperation and the lst and 4th postoperative week. Conclusions With higher encircling scleral buckle,the refractive change after buckling surgery may be caused primarily by the shallowing of anterior chamber and thickening of lens. (Chin J Ocul Fundus Dis, 1999, 15: 227-229)
Objective To observe the distribution of macular thickness and its relationship with axial length, gender, refraction status and race in six-year-old children. Methods 1543 six-year-old children from 34 schools in Sydney were randomly selected. The thickness of center macula（CM）, inner macula（IM）and outer macula（OM）were measured by optical coherence tomography（OCT）, the differences of macular thickness between different genders and races were comparatively analyzed. The axial length and refraction status of all children were measured by IOL Master and autorefractor RK-F1 respectively. Results The CM, IM and OM thickness of all those six-year-old children were normally distributed，on average they were 193.6, 264.3 and 236.9 mu;m respectively,the differences were statistically significant（t=0.40,0.08,0.20;P＜0.05）. The CM,IM and OM average thickness was 194.2,264.9,229.0 mu;m for boys and 189.3,262.5,231.5 mu;m for girls respectively. CM and IM thickness of boys were thicker than those in girls（t=0.15,0.11;P＜0.05）. The CM,IM and OM average thickness was 196.0,265.2,237.5 mu;m for White kids,186.0,262.3,236.5 mu;m for East Asia kids and 19.4,263.7,233.8 mu;m for Central East kids respectively. The CM and IM thickness of White and Central East children were significantly thicker than East Asia children (t=0.12,0.15;Plt;0.05）. There was no difference between these three races in OM thickness（t=0.16,P=0.6）. The IM and OM were thinner with longer axial length (Plt;0.05). The CM,IM and OM thickness was thicker with higher hyperopic degrees (Plt;0.05). Conclusions Macular thickness was normally distributed in six-year-old children and was significantly affected by gender, race, axial length and refraction status.