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find Keyword "心脏外科" 81 results
  • Current status of early cardiac rehabilitation management after cardiac surgery in China

    Cardiac rehabilitation can safely and effectively improve the quality of patient's life and reduce readmission rate and mortality after cardiac surgery. Early cardiac rehabilitation after cardiac surgery is an indispensable part of cardiac rehabilitation. It can speed up the recovery of patient's exercise endurance, prevention of postoperative complications, shorten the time of returning to the family, increase the confidence of sustained rehabilitation, and lay foundation and set rehabilitation targets for the later stage of cardiac rehabilitation. This paper reviews the development history of early cardiac rehabilitation after cardiac surgery, and summarizes the current status, problems and outlook of rehabilitation management in China.

    Release date:2019-08-12 03:01 Export PDF Favorites Scan
  • 缺血后处理在法洛四联症矫治术中的心肌保护作用

    目的 探讨缺血后处理对法洛四联症(TOF)患者的心肌保护作用,以改善患者的临床预后。 方法 将80例TOF择期行根治术患者随机分成两组,每组40例,对照组:行常规手术,不进行缺血后处理;实验组:给予2个或3个周期的缺血后处理。观察术后24 h正性肌力药物使用剂量、术后ICU监护时间、呼吸机辅助时间和住院时间,测定术前、术后4 h 、8 h 和20 h的肌酸激酶同工酶(CK-MB)、肌钙蛋白I(cTnI)的改变。 结果 2例患者死于术后低心排血量综合征。实验组术后多巴胺用量较对照组明显减小(Plt;0.01),ICU监护时间和呼吸机辅助呼吸时间均较对照组明显缩短(Plt;0.05);实验组术后4 h CK-MB和cTnI 均明显低于对照组(Plt;0.05)。随访78例,随访时间6个月,患者症状消失,活动耐力明显提高,无并发症发生。 结论 缺血后处理在TOF根治术中有心肌保护作用。

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
  • Evaluation and Prevention of Cardiac Risks in the Patients Undergoing Noncardiac Surgery

    随着人口的老龄化,越来越多的有症状或无症状的冠心病患者需接受非心脏外科手术。接受非心脏外科手术而死亡的患者大约有50%是由于心脏并发症所致[1]。围手术期发生的心脏并发症大约5%~10%为心肌梗死,主要发生于术后头3天,其病死率很高,可达32%~69%[2,3]。术后发生心肌梗死或不稳定型心绞痛的患者发生心血管问题的几率增加20倍[4]。因此,如何评估非心脏外科手术患者的心脏危险性,如何预防围手术期心脏并发症的发生,已成为外科医生十分关注的一个问题。

    Release date:2016-08-28 04:49 Export PDF Favorites Scan
  • Application of BiLevel Positive Airway Pressure Mechanical Ventilation on Cardiac Surgery Patients in Intensive Care Unit

    【摘要】 目的 探讨双水平无创正压通气(BiPAP)对心脏外科术后需要二次机械辅助通气患者的治疗效果。方法 2008年9月—2009年9月,收集心脏外科手术后成功脱离呼吸机辅助通气后心功能衰竭或呼吸功能衰竭需要二次机械通气的患者,符合纳入及排除标准者共53例,进行回顾性分析,根据治疗方案分为无创通气组(32例)和有创通气组(21例),在需要机械通气时(T1),机械通气后30 min(T2),机械通气后2 h(T3)及预计脱离机械通气时(T4),分别统计患者心率、血气分析等情况,比较氧分压、ICU停留时间及术后至出院时间。结果 给予辅助通气前,两组患者的心率及PO2无统计学差异(Pgt;0.05)。给予辅助通气后,无创通气组患者的心率由T1(130.8±21.10)次/min,下降到T2(125.60±21.36)次/min,T3(101.70±13.73)次/min,T4(87.40±9.35)次/min;PO2由T1(64.70±14.12) mm Hg,上升到T2 (121.40±30.19) mm Hg,T3 (140.40±25.29) mm Hg,T4 (132.90±16.33) mm Hg。有创通气组患者的心率由T1 (138.27±21. 39)次/min,下降到T2(118.18±18.03)次/min,T3(100.00±11.73)次/min,T4(87.00±10.70)次/min;PO2由T1 (61.45±13.56) mm Hg上升到T2(122.55±29.50) mm Hg,T3(138.91±24.77) mm Hg,T4(133.55±18.00) mm Hg。两组患者心率及PO2均较辅助通气前降低(Plt;0.05)。两组患者之间各时间点心率及PO2比较无差异(Pgt;0.05)。无创通气组的ICU停留时间及术后至出院时间分别为(1.75±2.97) d及(9.14±4.11) d,均低于有创通气组的(4.38±5.13) d及(14.00±0.82) d,有统计学意义(Plt;005)。结论 双水平无创正压通气可用于心脏外科术后需要二次机械通气的患者。

    Release date:2016-09-08 09:37 Export PDF Favorites Scan
  • 体外循环中乌司他丁对机体的保护作用

    乌司他丁(尿胰蛋白酶抑制剂)是由143个氨基酸组成,分子量为66 464u的酸性蛋白质,其冻干品为白色或淡褐色块状物或粉末;是从健康男性尿中分离纯化的糖蛋白,它有多种特殊的药理性质,为一种广谱酶抑制剂,对多种酶、糖和脂水解酶有抑制作用.在体外循环过程中由于机体处于一种非生理状态下,同时伴有缺血、缺氧和各种酶、炎性介质、自由基的大量释放,导致机体心脏、肺、肾等重要器官和血管内皮损伤.乌司他丁作为一种蛋白酶抑制剂能较为有效的竞争性或非竞争性抑制由体外循环非生理作用引发的一系列酶以及炎性介质的释放,同时起到保护机体重要器官的作用.

    Release date:2016-08-30 06:31 Export PDF Favorites Scan
  • Surgical Technique and Outcomes for Supracardiac Total Anomalous Pulmonary Venous Connection

    Objective To summarize the surgical experience of supracardiac total anomalous pulmonary venous connection(S-TAPVC) and study the surgical technique and outcomes for S -TAPVC. Methods Eightysix patients with S-TAPVC underwent the surgical repair from May 1985 to December 2007. There were 49 males and 37 females. The patients aged from 7 months to 35 years (mean 9.6 years) and weighed from 4.9 kg to 68.0 kg (mean 23.8 kg). The patients were divided into three groups by the approach for the anastomosis. There were 20 patients in groupⅠthrough the right atrium incision, 49 patients in group Ⅱ through the right and left atrium incisions and 17 patients in group Ⅲ through the top of the left atrium incision. The interrupt continuous anastomosis between the common pulmonary venous and the left atrium was used in all patients. The enlarged atrial septal defect(ASD) was repaired with autopericardium. The vertical vein was ligated if the postoperative left atrial pressure was less than 15 mm Hg. But the vertical vein was opened or just partialy ligated if the postoperative left atrial pressure was more than 15 mm Hg. Results There was no early operative death. The postoperative left atrial pressure in three groups were 9.3±3.2 mm Hg, 9.9±2.9 mm Hg and 11.6±3.8 mm Hg, respectively. The cases with open or just partly ligated vertical vein in three groups were 0 case (0%), 7 cases (14.3%) and 2 cases (11.8%), respectively. The cases of arrhythmia in three groups were 5 cases (25.0%), 15 cases (30.6%)and 1 case (5.9%). The severely low cardiac output syndrome occurred in 2 patients and reoperation for bleeding in 2 patients. The morbidity of arrhythmia in group Ⅲ was less than in group Ⅱ(P=0.042). Conclusion The outcome of surgical repair for S -TAPVC is satisfactory. The anastomosis through the top of the left atrium incision has low occurrence of arrhythmia. The anastomosis through the right and left atrium incision is easy to expose and to perform surgery, especial for old children and adult patients.

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
  • 心脏直视术后回输胸腔引流血30例

    目的 探讨心脏直视术后回输未经洗涤的胸腔引流血的安全性和该技术对术后胸腔引流血量及库血需要量的影响. 方法 观察60例冠状动脉旁路移植术患者,并将其分为回输组和对照组,每组30例,分别测定两组血红蛋白、红细胞压积、红细胞计数和血小板计数. 结果 两组术后胸腔引流血差别无显著性意义,回输组患者引流血回输量为150~780 ml,平均280±155 ml ,节省库血40%.两组患者均未发生术后高热. 结论 心脏直视术后回输未经洗涤的胸腔引流血是安全、经济的,并可减少库血需要量.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
  • Analysis of risk factors for diaphragmatic dysfunction after cardiovascular surgery with extracorporeal circulation: A retrospective cohort study

    ObjectiveTo clarify the risk factors of diaphragmatic dysfunction (DD) after cardiac surgery with extracorporeal circulation. MethodsA retrospective analysis was conducted on the data of patients who underwent cardiac surgery with extracorporeal circulation in the Department of Cardiovascular Surgery of Peking University People's Hospital from January 2023 to March 2024. Patients were divided into two groups according to the results of bedside diaphragm ultrasound: a DD group and a control group. The preoperative, intraoperative, and postoperative indicators of the patients were compared and analyzed, and independent risk factors for DD were screened using multivariate logistic regression analysis. ResultsA total of 281 patients were included, with 32 patients in the DD group, including 23 males and 9 females, with an average age of (64.0±13.5) years. There were 249 patients in the control group, including 189 males and 60 females, with an average age of (58.0±11.2) years. The body mass index of the DD group was lower than that of the control group [(18.4±1.5) kg/m2 vs. (21.9±1.8) kg/m2, P=0.004], and the prevalence of hypertension, chronic obstructive pulmonary disease, heart failure, and renal insufficiency was higher in the DD group (P<0.05). There was no statistical difference in intraoperative indicators (operation method, extracorporeal circulation time, aortic clamping time, and intraoperative nasopharyngeal temperature) between the two groups (P>0.05). In terms of postoperative aspects, the peak postoperative blood glucose in the DD group was significantly higher than that in the control group (P=0.001), and the proportion of patients requiring continuous renal replacement therapy was significantly higher than that in the control group (P=0.001). The postoperative reintubation rate, tracheotomy rate, mechanical ventilation time, and intensive care unit stay time in the DD group were higher or longer than those in the control group (P<0.05). Multivariate logistic regression analysis showed that low body mass index [OR=0.72, 95%CI (0.41, 0.88), P=0.011], preoperative dialysis [OR=2.51, 95%CI (1.89, 4.14), P=0.027], low left ventricular ejection fraction [OR=0.88, 95%CI (0.71, 0.93), P=0.046], and postoperative hyperglycemia [OR=3.27, 95%CI (2.58, 5.32), P=0.009] were independent risk factors for DD. ConclusionThe incidence of DD is relatively high after cardiac surgery, and low body mass index, preoperative renal insufficiency requiring dialysis, low left ventricular ejection fraction, and postoperative hyperglycemia are risk factors for DD.

    Release date:2025-07-23 03:13 Export PDF Favorites Scan
  • 保留后瓣及瓣下结构的二尖瓣置换术

    目的 总结保留后瓣及瓣下结构的二尖瓣置换术(MVR)的临床经验,并观察其与常规MVR比较的临床效果。方法 风湿性心瓣膜病患者54例,其中行保留后瓣及瓣下结构的MVR24例(保留二尖瓣后瓣组),行常规MVR30例(常规手术组),观察两组患者术前、术后3个月的左心室舒张期末内径(LVEDD)、左心室射血分数(LVEF)、左心室短轴缩短率(LVFS)等指标。结果 保留二尖瓣后瓣组无死亡患者,常规手术组死亡1例;保留二尖瓣后瓣组术后血管活性药物的用量、种类和呼吸机使用时间较常规手术组减少;术后3个月保留二尖瓣后瓣组LVEDD较常规手术组减小,LVEF较常规手术组增大(P〈0.05)。结论 保留后瓣及瓣下结构的MVR手术操作不复杂,不增加心内手术时间,有可能减少左心室破裂的危险,术中操作仔细可以避免卡瓣,术后心功能恢复较好,更适用于心功能较差、左心室较大的以二尖瓣关闭不全为主的患者。

    Release date:2016-08-30 06:26 Export PDF Favorites Scan
  • Application of Hemoglobin-based Oxygen Carriers in Cardiac Surgery

    Hemoglobin-based oxygen carriers (HBOCs) is a kind of blood substitutes. It is a separated, ultra-purified, modified human or bovine hemoglobin in a balanced saline solution. After modification, it has longer half-time, less renal toxicity, and better delivery of O2 even at low temperature and pH. Its shelf life is long and it dose not require cross-matching. In the field of cardiac surgery, the use of HBOCs can reduce the amount of transfusion postoperatively, and can be used in cardiopulmonary bypass priming and myocardial protection.

    Release date:2016-08-30 06:16 Export PDF Favorites Scan
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