Purpose To verify the effectiveness of combined B-scan ultrasonoscopy and ultrasound biomicroscopy(UBM)imagings in diagnosis of retinal detachments. Methods To contrast the manifestations in vitrectomy operations with the findings of preoperative combined B-scan ultrasonic and UBM examinations in 25 eyes of 25 cases in which 18 eyes with rhegmatogenous retinal detachment and 7 eyes with traumatic retinal detachment were included. Results B-scan ultrasonic imagings were divided into four types: type C,type V,type upsilon; and type gamma;,which included 6 eyes,2 eyes,4 eyes and 11 eyes respectively,and from type C to type gamma;,the retinal detachments manifested themselves from simple posterior segment proliferative vitreoretinopathy(PVR)to both anterior and posterior PVR.The imagings of UBM were divided into 3 types:shallow retinal detachment,retinal circumferential contraction and retinal anterior displacement,which reflected the degree of anterior PVR from lightness to severeness. Conclusions The technique of combined B-scan ultrasonoscopy and UBM can be used to access the severity of the retinal detachments,hence would be beneficial in diagnosing anterior and posterior PVR,designing the surgical precedures and assessing the prognosis. (Chin J Ocul Fundus Dis,1998,14:16-20)
Objective To test the hypothesis that the macular pigment may be a marker of foveal cone function and consequently the structural integrity of foveal cones.Methods Sixteen patients (32 eyes) diagnosed to have Stargardt dystrophy and three patients with full thickness macular holes by clinical criteria were studied with a scanning laser ophthalmoscopy (SLO) comparing argon laser blue and infrared images for the presence or absence of macular pigment (MP) in the fovea. An C++ computer based program was used to evaluate the density of MP. Eyes were graded into three categories: those without foveal macular pigment, those with partial pigment and those with normal amounts of macular pigment. These categories were compared with visual acuity determined by the Snellen chart. Results Thirteen eyes with a visual acuity of 20/200 or worse had no macular pigment in the fovea. Eleven eyes with visual acuity of 20/40 or better had a normal amount of macular pigment in the fovea and 1 eye had partial macular pigment. Eleven eyes with partial macular pigment had intermediary acuity value.Conclusions Foveal macular pigment is closely related to foveal cone acuity and therefore may be a marker for the presence of foveal cones. Infrared light is a sensitive indicator of early macular diseases.(Chin J Ocul Fundus Dis，2003，19：201-268)
【摘要】 目的 探讨全自动尿沉渣分析仪在尿管型检测中的应用。 方法 收集尿管型患者晨尿标本836份。所有标本均经尿干化学分析仪检测Pro≥1+或尿沉渣分析仪提示有管型。采用UF100全自动尿沉渣分析仪和显微镜检测管型，对比分析两者的检测结果。 结果 836份标本中，UF100全自动尿沉渣分析仪检测阳性者320例，占38.28%；显微镜检测阳性者195例，占23.33%。其中UF100全自动尿沉渣分析仪的假阳性率为26.52%，假阴性率为23.08%。UF100尿沉渣分析仪与显微镜检测管型的阳性结果比较，差异有统计学意义（Plt;0.01）。 结论 UF100全自动尿沉渣仪能快速筛检尿沉渣，但存在一定的假阴性，必须同时将其检测结果与尿干化学结果结合考虑以决定是否再进行显微镜检测，减少假阴性以防止漏检。【Abstract】 Objective To investigate the application of UF-100 full-auto urine sediment analyzer in detecting cylindruia. Methods 836 specimens with cylindruia were selected. All the specimens with Pro≥1+ were dectected by chemical dipstick or cylindruia by urine sediment analyzer. The cast were detected by urine sediment analyzer and microscope, and the results were compared. Results Of 836 specimens, 320 positive samples(38.28%) were found by UF-100 while 195 (23.33%) were found by microscope. False positive rate and false negative rate of UF100 were 26.52% and 23.08%. Compared the results of urine sediment analyzer with microscope, the difference was statistically significant (Plt;0.01). Conclusions UF100 can detect urinary cast quickly, but there is a little high false negative rate. So we should consider urine sample whether to be detected by microscope compared with results of UF100 and chemical dipstick.
Objective To observe the expression of Nogo66 receptor （NgR）in ratsprime; retina during the postnatal development． Methods The expression of NgR in 48 rats were observed by immunofluorescence histochemistry and laserconfocal microscopy 0, 3, 7, 14, 21, 35, 49, 63 days after birth, with 6 rats in each group, respectively． Results The expression of NgR is positive in the retina in the whole duration of growth, and the fluorescence pigmentation was located around the ganglion cell nuclaear. Conclusion The positive expression of NgR suggests that the interaction of NgR and CNS myelin inhibitors not only inhibit neuronal plasticity but also promote it, which could regulate neuronal plasticity.