Fetal heart rate (FHR) baseline estimation is of significance for the computerized analysis of fetal heart rate and the assessment of fetal state. In our work, a fetal heart rate baseline correction algorithm was presented to make the existing baseline more accurate and fit to the tracings. Firstly, the deviation of the existing FHR baseline was found and corrected. And then a new baseline was obtained finally after treatment with some smoothing methods. To assess the performance of FHR baseline correction algorithm, a new FHR baseline estimation algorithm that combined baseline estimation algorithm and the baseline correction algorithm was compared with two existing FHR baseline estimation algorithms. The results showed that the new FHR baseline estimation algorithm did well in both accuracy and efficiency. And the results also proved the effectiveness of the FHR baseline correction algorithm.
目的探讨肝外型门静脉高压症的外科治疗经验。方法1993年1月至1999年12月，我科收治肝外型门静脉高压症42例，男19例，女23例，年龄8~58岁，平均24.6岁，经B超、动脉造影、脾静脉造影和术中探查，诊断为门静脉血栓形成34例，内脏动静脉瘘5例，终末支门静脉纤维化2例，肝动脉瘤压迫门静脉1例。根据病变不同，分别给予肠腔分流、脾肾分流、经导管溶栓及栓塞或动静脉瘘切除等治疗。结果术后2例死亡，并发肝脓肿1例，肠坏死1例，其余患者均获满意疗效。有31例随访5个月~6年无复发。结论肝外型门静脉高压症只要选择好合理的治疗方法，可获满意疗效，且远期效果良好。
Objective To investigate the efficacy of LDL-C lowering treatment on NSTE-ACS, and to analyze the target LDL-C level for clinical treatment. Methods PubMed, EMbase, the Cochrane Central Register of Controlled Trials, Web of Science databases were searched up to January 2016 for randomized controlled trials assessing the effects of LDL-C lowering therapy on major adverse cardiac events (MACE) in patients with NSTE-ACS. Two reviewers independently screened litertures, extracted data and assessed the risk of bias of included studies, and then meta-analysis was performed by using Stata12.0 and RevMan 5.3 software. Result A total of 12 RCT including 4 702 individuals with NATE-ACS were included. The results of meta-analysis showed that, compared with the control group, the statin group could significantly reduced the risk of MACE (RR=0.68, 95% CI 0.549 to 0.834,P=0.000). With 18.68 months of follow-up, patients in target LDL-C level from over 70 mg/dL to less than 100 mg/dL group had lower risk of MACE than other LDL-C level group. When LDL-C lower 20% to 40% than baseline with 28.99 months follow-up, patients in target of LDL-C level from over 70 mg/dL to less than 100 mg/dL group had lowest risk of MACE (RR=20.143, 95% CI 6.946 to 58.414,P=0.000). Conclusion LDL-C lower treatment can lower the risk of MACE in patients with NSTE-ACS. Patients in target LDL-C level from over 70 mg/dL to less than 100 mg/dL group have relatively low risk of MACE, in which patients who lower 20% to 40% LDL-C than baseline will get more benefits from LDL-C lowering therapy.
目的：探讨3D网塞在腹股沟疝修补术中的应用。方法：随机选取30例腹股沟疝患者用3D网塞行无张力疝修补术。结果：本组平均手术时间35 min，平均术中出血15 mL。术后8~24 h下地活动，均未给镇痛药，无手术死亡、无切口感染、阴囊血肿等并发症，患者局部舒适性好，异物感不明显，随访5~10个月，无一例复发。结论：使用3D网塞作为充填式疝修补材料具有手术创伤小、恢复快，患者局部舒适性好，复发率低等优点。
Identification of real-time uterine contraction status is very significant to labor analgesia, but the traditional uterine contraction analysis algorithms and systems cannot meet the requirement. According to the situations mentioned above, this paper designs a set of algorithms for the real-time analysis of uterine contraction status. The algorithms include uterine contraction signal preprocessing, uterine contraction baseline extraction based on histogram and linear iteration and an algorithm for the real-time analysis of uterine contraction status based on finite state machines theory. It uses the last uterine status and a series of state transfer conditions to identify the current uterine contraction status, as well as a buffer mechanism to avoid false status transitions. To evaluate the performance of the algorithm, we compare it with an existing uterine contraction analysis algorithm used in the electronic fetal monitor. The experiments show that our algorithm can analyze the uterine contraction status while monitoring the uterine contraction signal in a real-time. Its sensitivity reaches 0.939 9 and its positive predictive value is 0.869 3, suggesting that the algorithm has high accuracy and meets the need of clinical monitoring.
Objectives To evaluate the methodological quality of published clinical practice guidelines for benign prostatic hyperplasia. Methods PubMed, EMbase, CNKI, WanFang Data, VIP and CBM databases, website of Yimaitong, and international authoritative guide platforms were electronically searched to collect the relevant clinical practice guidelines or consensus for benign prostate hyperplasia. The retrieval covered the time up to December 13th, 2016. Literatures were independently screened by 2 reviewers. After data extraction, the methodological quality of included guidelines was evaluated by 4 reviewers using the AGREE Ⅱ. Each domain score was calculated and the intraclass correlation coefficient was used to evaluate the consistency among the reviewers. Results A total of 15 clinical practice guidelines were included. The mean scores for the six domains in AGREE Ⅱ were: 72%, 38%, 30%, 58%, 16%, and 40%, respectively. The intraclass correlation coefficient was larger than 0.87, which indicated the total consistency was well. Conclusions The quality of clinical practice guidelines for benign prostatic hyperplasia is not satisfactory as expected. They are heterogeneous in quality and some requires improvement. Guidelines are required to be further developed in methodology in future, especially in three domains, including participants, preciseness and applicability of the design.