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find Author "林丽娜" 2 results
  • 左旋精氨酸对体外循环缺血再灌注损伤心肌的保护作用

    目的 探讨左旋精氨酸对体外循环(ECC)下心肌缺血再灌注损伤的防护作用.方法 16例ECC下行心脏手术患者随机分成对照组和治疗组,分别于主动脉阻断前、开放后2小时、4小时、8小时测定血浆一氧化氮(NO)水平、乳酸脱氢酶(LDH)和肌酸磷酸激酶(CPK)活性.结果 主动脉开放后不同时点,对照组NO水平显著下降,LDH,CPK活性明显增强,与阻断前比较差异均有显著性(P<0.05和P<0.01);治疗组NO水平无明显变化(P>0.05),LDH,CPK活性轻度增加,且与对照组比较差异有显著性(P<0.05和P<0.01).结论 左旋精氨酸通过提高机体NO水平而保护ECC下缺血再灌注损伤的心肌.

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • Clinical study on minimally invasive weaving technique for pectus carinatum

    ObjectiveTo explore the practical feasibility of the weaving technique for pectus carinatum.MethodsFrom January 2011 to December 2018, a total of 51 patients with pectus carinatum, including 47 males and 4 females at age of 9-29 (13.7±2.9) years, were applied with minimally invasive waving technique for the correction. The steel plate was inserted through the subcutaneous layer, intercostal space and over the sternal surface under direct thoracoscopic vision. The number of implanted steel plates was determined by the degree of chest wall deformity. The steel plate was removed 2 years after surgery.ResultsAll the operations were successfully completed, the average operation time was 63.9±15.8 min, the amount of bleeding was 19.8±8.8 mL, and the duration of postoperative hospitalization was 4.6±1.6 d. The adverse events included intercostal artery injury (n=2), pneumothorax (n=4), pleural effusion (n=3) and skin rupture (n=1). And there were 29 patients of moderate pain (numerical rating scale 4-6 points) on the first day after surgery, but no patient was asked to remove the steel palate due to intolerable discomfort. All patients were followed up after plate placement. Of the 51 patients, the plates were removed in 37 patients until 2 years after placement, and the duration of postoperative hospitalization was 1.4±0.5 d. After 33 (1-48) months of routine follow-up after the removal of the plate, 22 patients achieved excellent outcomes and 9 patients with good outcomes. Besides, there were 5 patients with fair outcome and 1 patient with poor outcome. No adverse effect was found in growth and development after the steel plate placement.ConclusionMinimally invasive weaving technique is a safe, feasible, effective and individualized operation for pectus carinatum with substantial thoracic reconstruction.

    Release date:2019-10-12 01:36 Export PDF Favorites Scan
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