Post-stroke cognitive impairment (PSCI) which has been a barrier to the rehabilitation, could be prevented and treated. Early assessment of cognitive impairment, as well as diagnosis and comprehensive interventions of PSCI would improve rehabilitation of stroke patients. The rehabilitation, as an important component of the comprehensive intervention, could improve cognitive function, delay disease progression, and optimize the daily life. The widely-used rehabilitation methods include cognitive intervention, exercise training, music therapy, and neuromodulation techniques, etc. Comprehensive cognitive training covering multiple cognitive domains and multimodal intervention can significantly improve the overall cognitive function of patients. The research in the PSCI field is still in its infancy in China. Thus, It is necessary to pay more attention to the PSCI clinically, and unveil the unkown area in PSCI.
ObjectiveTo observe the effectiveness of oral glucosamine hydrochloride and cupping therapy in the treatment of knee osteoarthritis. MethodsA total of 113 patients treated from February 2013 to February 2015 were randomly divided into three groups. All the three groups of patients underwent conventional treatment. The Cupping treatment group had 39 patients; 37 patients were treated with oral glucosamine hydrochloride, and another 37 patients accepted combined treatments of cupping therapy with oral glucosamine hydrochloride. Six weeks after treatment, pain degree of the patients and Lequesne index were used to assess the clinical efficacy of the treatments. Patients who had oral glucosamine hydrochloride underwent routine examinations of blood and urine, and received liver and kidney examinations. One year later, telephone follow-up was conducted to observe long-term efficacy. ResultsSix weeks after treatment, the combined treatment group was significantly better than the other two groups in terms of pain relief degree and effective rate (P ＜ 0.05) . One year after treatment, the combined treatment group and the oral treatmentgroup had a significant advantage over the cupping treatment group (P ＜ 0.05) , while there was no significant difference between the combined treatment group and oral treatment group. ConclusionsThe combined oral glucosamine hydrochloride and cupping therapy has an obvious short-term efficacy, which quickly relieves pain and improves the activity function of the knee. Oral glucosamine hydrochloride has a very good effect in the long-term treatment of osteoarthritis.
Objective To discuss left ventricular reconstruction methods and effectivness in patients with left ventricular aneurysm after myocardial infarction. Methods Between June 2003 and August 2008, 23 patients with left ventricular aneurysm after myocardial infarction were treated. Of them, 13 were male and 10 were female with an average age of 61.2 years (range, 47-74 years). According to New York Heart Association (NYHA) criteria for cardiac function, there were 3 cases of grade I, 6 cases of grade II, 10 cases of grade III, and 4 cases of grade IV. The coronary arteriongraphy showed singlevesseldisease in 2 cases, double-vessel disease in 5 cases, triple-vessel disease in 16 cases. The locations of ventricular aneurysm were the apex cordis in 18 cases, antetheca and parieslateral is in 4 cases, and interior wall in 1 case. The left ventricular ejection fraction was 36.52%± 12.15%, and left ventricular diastol ic final diameter was (62.30 ± 6.52 ) mm. Nine patients received standard l inear repair, 6 patients received standard l inear repair after endocardial ring shrinkage, and 8 patients received patch suture after endocardial ring shinkage. Results Two cases died perioperatively, and re-thoracotomy was performed to stop bleeding in 1 case. Incisions healed by first intention in the other patients without early compl ication. Twentyone patients were followed up 7-48 months (median, 19 months). At 6 months after surgery, the left ventricular ejection fraction 46.52% ± 9.41% were significanly improved when compared with that at preoperation (t=2.240, P=0.023); the left ventricular diastol ic final diameter (52.23 ± 5.11) mm were significantly decreased when compared with that at preoperation (t=2.170, P=0.035). The cardiac function according to NYHA criteria was at grade I in 8 cases and at grade II in 13 cases. One patient died of cerebral hemorrhage at 18 months after operation and the activities of daily l iving recoverd in the others. Conclusion Individual theraputic methods are used according to patients’ different conditions for left ventricular aneurysm after myocardial infarction.
目的 探讨胰十二指肠切除术胰与消化道重建方法的选择。方法 对我院1989～1999年施行的胰十二指肠切除术后胰胃吻合83例行回顾性总结，其中行经典的胰十二指肠切除术76例，保留幽门的胰十二指肠切除术7例。胰胃吻合是残余胰腺与胃后壁间断单层植入式吻合。结果 住院病死率为2.4%（2/83）； 并发症发生率为25.3%（21/83），其中胰瘘3例，胆瘘2例，吻合口出血3例，切口裂开5例，胃排空迟缓5例，腹腔感染1例，胸腔积液1例，肠梗阻1例。结论 胰胃吻合术简便、安全，是降低术后胰瘘的胰肠重建方法。
The anti-oxidative ability of cirrhotic liver tissues was evalated in rat models of cirrhotic liver which were induced by injecting carbon tetrachloride subcutaneously. The superoxide dismutase (SOD), general anti-oxidative ability (GAOA) and malonyldiadehyde (MDA) levels were determined in cirrhotic and normal rats. It was found that SOD and GAOA leves decreased (Ｐ＜0.05, Ｐ＜0.01)respective and MDA level increased(Ｐ＜0.05) significantly in cirrhotic rat liver. The results suggest that cirrhotic livers hav little ability to eliminate the superoxide free radicals as compared with normals and are more sensitive to is chemic-reperfusion or other unjurie.