The contents of lipid peroxides(LPO)and vitamin E(V.E)and some functional index and histologic changes in the lungs from the the rabbit models of acute cholangitis of severe type(ACST)were measured dynamically.The results revealed that the V.E content decreased strikingly from 6 hours and the LPO level increased progressivelg from 12 hours in the lungs.Simultanuosly,the congestion and neutrophil infiltreation in the lung mesenchyme,and the endothelial cell damage and thrombosis in the lung blood capillaries had been observed.These suggest that acute lung injury induced by ACST is referable to the lipid peroxidation damage to the lung blood capillaries which is due to increased LPO and decreased antioxidants including V.E.
目的 探讨戴戒术治疗下肢原发性深静脉瓣膜功能不全的疗效和手术经验。方法 35例(47条肢体)下肢原发性深静脉瓣膜功能不全采用GoreTex人造血管行戴戒术治疗，在股浅静脉最高位第一对瓣膜下缩小原静脉周径1/4～1/3。结果 术后随访6个月至2年半，所有患者症状和体征完全或基本消失，9条肢体慢性溃疡于手术后8周内愈合。结论 该手术简便、安全易掌握，疗效满意，为提高本手术效果，应做到： ①熟悉掌握本术式的技术要点； ②合理掌握手术适应证和手术时机。