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find Keyword "研究现状" 15 results
  • 外周T细胞淋巴瘤的治疗进展

    T细胞淋巴瘤(TCL)是来源于T淋巴细胞的一类恶性淋巴肿瘤,目前尚无统一的最佳治疗方法。虽近年有新的治疗药物,但都只基于少量的病例或小规模的Ⅱ期临床试验。美国国立卫生研究院对于非皮肤型外周TCL的原则为一线治疗方案首选临床试验。且一线巩固方案除低危患者外,应考虑行大剂量化学治疗(化疗)联合造血干细胞移植。另外由于间变性淋巴瘤激酶基因阳性的间变大细胞淋巴瘤预后较好,对处于完全缓解期者无需行干细胞移植。二线治疗方案中,对于耐受大剂量化疗的患者首选临床试验。对于不能耐受大剂量化疗的患者首先考虑参加临床试验,其次使用新药(如阿仑单抗、硼替佐米、地尼白介索、吉西他滨等)及放射治疗,或根据原癌基因或抑癌基因进行治疗。现就其治疗进展作一综述。

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  • Evaluation of projects funded by National Natural Science Foundation of China

    Objectives To analyze the status quo of projects on pension services funded by the National Natural Science Foundation of China (NSFC), with the aim of enlarging the perspective and horizon of related studies, and improving both the quantity and quality of such projects in NSFC. Methods NSFC website was systematically searched to collect information of pension service projects funded by NSFC from 2008 to 2017. SPSS 19.0 software was subsequently applied to analyze the characteristics of the projects in terms of study type, regional distribution, profession and institution, and fund scale, etc. Results A total of 39 projects on pension service were included, among which 12 were focused on related strategies (30.8%), 11 on related models (28.2%), and 6 on the effects of different interventions (15.4%). The 39 projects were unbalanced in terms of geographical distribution, institutions and research types. Conclusions NSFC should facilitate the research of pension service by expanding the related fund scale, increasing the fund support, strengthening the exchange of domestically different regions, and enhancing international cooperation.

    Release date:2019-01-15 09:51 Export PDF Favorites Scan
  • Research Progress of Thoracic Duct Surgery

    Thoracic duct is the largest lymphatic vessel in the body. It originates from the chyle pool in the abdominal cavity, upward across aortic hiatus of the diaphragm into the right thoracic cavity, and finally importing into the left jugular vein angle. Thoracic duct plays a very important role in the transporting process of the body's lymph and chylous fluid. More than 70% of the lymph and chylous fluid transport through it into the blood. If the thoracic duct was damaged, it would lead to fluid and electrolyte imbalance, immune dysfunction, malnutrition and the patient's life would be endangered when it was serious. Therefore, the clinical significance of the thoracic duct is always a hot research issue. Through unremitting exploration in recent years, we have a further understanding about structure and function of the thoracic duct. And we used this to remould and ligate it to cure some intractable disease. Now we summarize the research progress as follows.

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  • The current research status of evidence-based health policy briefs: a visual analysis

    Objective To analyze the current research status, hotspots and development trends in the field of evidence-based health policy briefs at home and abroad. Methods Computer searches of Web of Science Core Collection and CNKI databases for studies related to evidence-based health policy briefs were conducted, and the timeframe of the searches was from the establishment of the databases to August 6, 2024. Charticular, VOSviewer and CiteSpace software were used to visualize and analyze the countries, institutions, journals, authors and keywords of the included literature. Results A total of 145 relevant studies were included, of which 141 were in English and 4 were in Chinese. The number of articles in English showed an overall increasing trend; the country with the largest number of articles was the United States; the organization with the largest number of articles was the World Health Organization; the journal with the largest number of articles was Frontiers in Public Health; and the hot keywords in recent years focused on the food and nutritional safety system, cardiovascular disease, obesity, impact, and public health policy. The research related to "healthcare" and "knowledge translation" is expected to become a frontier hotspot. The number of Chinese studies was relatively small, and the research content involved policy briefs and policy brief methodology in the field of public health. Conclusion Future research may focus on policy briefs on health care, food and nutrition, cardiovascular disease, obesity and other health issues, their impact and the use of policy briefs in the formulation of public health policies. Currently, there is a significant difference between domestic and foreign research in the field of evidence-based health policy briefs, foreign research has tended to mature, while the domestic is still in the embryonic stage, there is an urgent need to enrich the methodological system, enrich the content of the study, and in the future, we can learn from the advanced experience of foreign countries and integrate multidisciplinary research methods, in order to promote the improvement and sustainable development of the field of evidence-based health policy briefs in China.

    Release date:2025-03-19 02:08 Export PDF Favorites Scan
  • Study on the reporting checklist of technical specifications for traditional Chinese medicine

    Technology in traditional Chinese medicine (TCM), which has a long history, provides excellent traditional culture and valuable spiritual wealth in China. TCM standardization technology will provide an important basis for guiding and evaluating the professional level and service quality of technicians in TCM. And it is also conducive to the sustainable development of TCM technology. However, at present, there is no relevant research on the development process of technical specifications for TCM. So, the urgent need is how to develop standardized technical specifications, and apply them to patients in practice. Therefore, this study first convened relevant experts, including TCM clinical experts, epidemiologists, methodology experts, etc., to form the core expert group, implementation group and quality assurance task group. According to the personnel functions, they are divided into technical specification steering committee, consensus expert group, secretariat group, external review group, evidence evaluation group, etc. Then, the initial entries are collected by systematically searching the current TCM technical guidelines, consensus and specifications and referring to the existing technical specifications. Finally, expert opinions were collected based on the Delphi survey, and the final reporting checklist of technical specifications for TCM was formed after consensus discussion. The study can provide evidence-based methodological guidance for the development of TCM technical specifications, and promote the standardization and internationalization of TCM technical specifications.

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  • 留置鼻胃管位置判断方法应用及研究现状

    针对目前国内外临床确认留置鼻胃管位置的方法,该文分析和总结了各国相关的指南或专家推荐,对检测依据、相关研究和国内外应用情况现状进行了综述,以期为临床护理工作者提供参考和借鉴。通过引进国外适用方法,应用于临床留置鼻胃管位置的正确判断,有利于保障患者鼻饲安全,减轻患者痛苦,减少不良事件的发生,促进护理质量的持续改进。

    Release date:2017-10-27 11:09 Export PDF Favorites Scan
  • Application and research status of bioactive glass in bone repair

    ObjectiveTo summarize the clinical application and research status of bioactive glass (BAG) in bone repair.MethodsThe recently published literature concerning BAG in bone repair at home and abroad was reviewed and summarized.ResultsBAG has been widely used in clinical bone repair with a favorable effectiveness. In the experimental aspect, to meet different clinical application needs, BAG has been prepared in different forms, such as particles, prosthetic coating, drug and biological factor delivery system, bone cement, and scaffold. And the significant progress has been made.ConclusionBAG has been well studied in the field of bone repair due to its excellent bone repair performance, and it is expected to become a new generation of bone repair material.

    Release date:2020-06-15 02:43 Export PDF Favorites Scan
  • Current research status of patient-reported outcomes in the field of venous thromboembolism

    ObjectiveTo summarize the applied research status on the evaluation tools of patient-reported outcome at home and abroad in patients with venous thromboembolism (VTE). MethodBy searching and analyzing the literatures, this paper summarized the concept, evaluation tools and application status of patient-reported outcome in the field of VTE. ResultsThe patient-reported outcomes can more comprehensively and accurately evaluate the disease burden and treatment effect of patients with venous thromboembolism, and can help doctors better understand patients' needs and guide individualized treatment and rehabilitation plans. ConclusionsPatient-reported outcome has a broad application prospect in the field of venous thromboembolism. Further promotion and application of patient-reported outcome can promote the development of medical research and provide reference guidelines for improving the management of patients with venous thromboembolism.

    Release date:2023-12-26 06:00 Export PDF Favorites Scan
  • Research status of patient-reported outcome in esophageal carcinoma surgery

    Esophageal carcinoma is a malignant tumor with high morbidity and mortality worldwide, and surgery is the main treatment currently. With the development of patient-centered care, the effect of surgery should not be limited to the improvement of the incidence of postoperative complications, mortality and other indicators. It is also important to provide experience related to disease and surgery from the perspective of patients. Therefore, more and more attention is paid to patient-reported outcomes by scholars. This paper will provide an overview of the international widely used, reliable and effective scales and researches about patient-reported outcomes in esophageal carcinoma.

    Release date:2022-12-28 06:02 Export PDF Favorites Scan
  • Research status of peripherally inserted central catheter: a bibliometric analysis based on Foreign Medical Retrieval System

    ObjectiveTo explore the trend and hotspots of research in the field of peripherally inserted central catheter (PICC), so as to provide a reference for clinical nursing and nursing research in the field of vascular access in China.MethodsAll PICC-related articles from 1806 to November 22nd, 2018 were searched in the Foreign Medical Retrieval System. The publication amount, year of publication, language, country, journals and impact factor, high-yield authors and high-frequent medical subject headings (MeSH) of the PICC-related articles were analyzed by using frequency, cumulative frequency, and constituent ratio.ResultsA total of 1 550 articles were included. They were published in 586 journals, of which 393 were included in Science Citation Index. English was the dominant publication language, and the top high-yield country was the United States. The top 16 high-yield authors published 199 articles, the top 3 of whom all had published co-operative papers, ranging from 1 article to 19 articles. The top 3 high-frequent MeSHs were “Catheters, Indwelling” “Catheterization, Central Venous” “Central Venous Catheter”.ConclusionsPICC has become a hotspot in clinical research, and the publication amount of relative literature has increased rapidly since 2000. Chinese scholars should improve their English and carry out multi-center cooperative research to improve the quality of PICC-related literature.

    Release date:2021-09-24 01:23 Export PDF Favorites Scan
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