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find Keyword "科学" 356 results
  • Vitreoretinal surgery using the 25G transconjunctival sutureless vitrectomy system under topical anesthesia

    Objective To evaluate the indications, effectiveness and complications of vitreoretinal surgery using the 25G transconjunctival sutureless vitrectomy system (TSV25G) under the topical anesthesia. Methods The clinical and follow-up data of 22 eyes of 22 patients undergone vitreo-retinal surgery using TSV25G under the topical anesthesia were retrospectively analyzed. All of the patients were monocular sickened, including idiopathic macular hole in 10 eyes, idiopathic macular pucker in 6, vitreoretinal traction syndrome in 4, and vitreous hemorrhage associated with branch retinal vein occlusion in 2. Peeling of epiretinal membrane and/or internal limiting membrane, intra ocular laser coagulation, air-fluid exchange and tamponiding of C3F8 were performed according to the condition of diseases. The postoperative follow-up was 1-11 months, with the mean duration of 6.4 months. The effect of analgesia, cooperation with the patients, operative effect and complications in and after the surgery were observed. Results The operations finished successfully in all of the eyes under the topical anesthesia. The operation duration ranged from 20 to 25 minutes with average of 22 minutes. The patients cooperated with the doctor well without any discomfort. Two days after the surgery, edema of the wounded conjunctiva was found, and recovered 7 days later. A light pigment dot on the surface of the sclera could be seen at the first month. The complic ations included transient increasing of intraocular pressure in 2 eyes, feather-like opacity of lens in 5 eyes, vitreous hemorrhage in 1 eye, and air-bleb under conjunctiva in 2 eyes. No other complications related with the cut were fo und. The macular hole closed in 9 eyes with idiopathic macular hole, and the other 1 had the smaller but not closed hole. Idiopathic macular pucker, vitreoretinal traction syndrome, and vitreous hemorrhage associated with branch retinal vein occlusion were cured successfully. Conclusions Vitreoretinal surgery using the TSV25G under the topical anesthesia has many advantages such as simple procedure, short operation time, micro-invasion, less complications and rapid revovery, and mainly serves simple manipulation in some simple diseases such as idiopathic macular hole, vitreo-retinal traction syndrome, and simple hemorrhage. (Chin J Ocul Fundus Dis,2004,20:133-136)

    Release date:2016-09-02 05:58 Export PDF Favorites Scan
  • Scientific and Humanistic Spirit in Evidence-Based Medicine

    Evidence-based medicine emphasizes that treatment must be based on the following elements : the latest and best evidence, clinicians' expertise and patients' preference. Evidence-based medicine embodies the ethos both to explore medical science and to respect patients' values. Evidence-based medicine is an integration of the scientific and the humanistic spirit.

    Release date:2016-09-07 02:25 Export PDF Favorites Scan
  • 黄斑裂孔手术治疗中内界膜的处理

    黄斑裂孔手术中内界膜(internal limiting membrane,ILM)剥除的有效性尚有许多争议。目前,多数研究者提倡进行ILM的剥除。因ILM的剥除提高了黄斑裂孔手术的解剖成功率,并使视力明显提高,且缩短了手术后俯卧位的时间;但在手术适应证的选择上还存在分歧。文献报道的资料由于标准不同,难以进行统计学方面比较。只有前瞻、随机、双盲、足够病例的临床试验,进一步加强临床追踪以及随着黄斑裂孔手术方式、技巧的不断改进完善,进一步验证ILM剥除的利弊,才能对其做出全面客观的评价。 (中华眼底病杂志,2003,19:201-268)

    Release date:2016-09-02 06:00 Export PDF Favorites Scan
  • Prognosis of idiopathic and traumatic macular holes treated by pars plana vitrectomy

      Objective To evaluate and compare the prognosis of idiopathic macular holes (IMH) and traumatic macular holes (TMH) treated by pars plana vitrectomy (PPV).Methods The clinical data of 72 IMH eyes and 55 TMH eyes, which were treated by PPV between November 2001 and December 2007, were retrospectively reviewed. The visual outcomes and macular anatomic closure were evaluated, and their relationships with prognostic factors including the size of macular hole (MH), preoperative visual acuity (VA) and duration of disease were analyzed.Results The closure rate of IMH (100.0%) was significant higher than that of TMH (85.5%) (P=0.001). The postoperative VA of IMH and TMH were (0.25plusmn;0.02) and (0.21plusmn;0.21) respectively,both significantly increased compare to their preoperative VA (t=-6.841,-4.093; P=0.000). VAincreased IMH and TMH eyes had same VA (chi;2=3.651,P=0.07). PrePPV VAge;0.1 IMH eyes had better outcomes than PrePPV VA<0.1 IMH eyes (chi;2=12.04, P=0.001), while PrePPV VA had no effects on TMH outcomes (chi;2=0.371,P=0.486). IMH eyes with small holes had better outcomes (t=2.476,P=0.016), and TMH eyes with small holes had better closure (t=-4.042, P<0.001). The duration of disease had no significant influence on TMH visual (chi;2=0.704, P=0.401) and anatomic (chi;2=0.166, P=0.684) outcomes. Conclusions PPV is an effective treatment for MH. The closure rate of IMH is higher than that of TMH. The diameter of MH and preoperative VA are major factors for IMH outcomes, and the duration of disease and preoperative VA have no effects on postoperative VA in TMH.

    Release date:2016-09-02 05:41 Export PDF Favorites Scan
  • ADVANCES IN CLINICAL APPLICATION OF HERNIOPLASTY BY HIGH MOLECULAR MATERIAL

    Objective To study the advances in clinical application of hernioplasty by high molecular material. Methods The literature in the recent years on the advances of hernioplasty by high molecular material was reviewed. Results At present time many operative techniques of hernioplasty by high molecular material have been developed. The representative techniques were ①Rives-Stoppa′s mesh inlay hernioplasty; ②Lichtenstein′s tesion-free herniorrhaphy; ③mesh plug hernioplasty; ④Gilbert′s sutureless hernioplasty; ⑤laparoscopic inguinal hernioplasty. The reparing high molecular material was divided into absorbable and unabsorbable material, the former included polyglycolic-acid and polyglaction, the later consists of polypropylene polyester and expanded polytetrafluoroethylene.Conclusion The clinical application of henioplasty by high molecular material is increasing. According to the hernia type and patient condition, excellent outcome will be achieved by the application of proper repairing method and repair material.

    Release date:2016-09-08 01:59 Export PDF Favorites Scan
  • 利用自动病变检测规划立体定向脑电图:可行性回顾性研究

    本回顾性横断面研究评估了将深度学习的难治性癫痫患儿的结构性磁共振成像(MRI)纳入到规划立体定向脑电图(SEEG)植入的可行性和潜在益处。本研究旨在评估自动病变检测与 SEEG 检测出癫痫发作起始区(SOZ)之间的共定位程度。将神经网络分类器应用于基于皮层 MRI 数据的三个队列:① 对 34 例局灶性皮质发育不良(FCD)患者的神经网络进行学习、训练和交叉验证;② 对 20 名健康儿童对照者进行特异性评估;③ 对 34 例患儿纳入 SEEG 植入计划的可行性进行了评价。SEEG 电极触点的坐标与分类器预测的病变进行核验。临床神经生理学家鉴定癫痫发作起源和易激惹区的 SEEG 电极触点位置。若 SOZ 坐标点和分类器预测的病变之间的距离<10 mm 则被认为是共定位的。影像学诊断病灶的分类敏感度为 74%(25/34)。对照组中未检测到异常(特异性=100%)。在 34 例 SEEG 植入患者中,21 例有局灶性皮层 SOZ,其中 8 例经病理证实为 FCD。分类器正确地检测了这 8 例 FCD 患者中的 7 例(86%)。组织病理学存在异质性的局灶性皮层病变患者中,62% 的患者分类器输出结果与 SOZ 之间存在共定位。3 例患者中,电临床提示为局灶性癫痫,SEEG 上无 SOZ 定位点,但在这些患者中,分类器识别了尚未植入的额外异常点。自动病变检测与 SEEG 之间的共定位存在高度的一致性。 我们已经建立了一个框架,将基于深度学习的 MRI 自动病变检测纳入到 SEEG 植入计划。我们的发现支持了对自动 MRI 分析的前瞻性评估,以规划最佳电极植入轨迹方案。

    Release date:2021-08-30 02:33 Export PDF Favorites Scan
  • 外伤性脉络膜上腔出血合并视网膜脱离的玻璃体视网膜手术治疗

    Release date:2016-09-02 05:42 Export PDF Favorites Scan
  • 吊顶灯辅助下23 G玻璃体切割手术治疗外伤性植入性虹膜囊肿的疗效观察

    Release date:2016-09-02 05:37 Export PDF Favorites Scan
  • Surgical management of osteoarthritis of the knee: evidence-based clinical practice guideline methodological interpretation and recommendations explanation

    Surgical management of osteoarthritis of the knee: evidence based guideline contains 38 recommendations pertaining to the preoperative, perioperative, and postoperative care of patients with knee osteoarthritis (KOA) who are considering surgical treatment. Compared with the domestic consensus on diagnosis and treatment for KOA, this clinical practice guideline (CPG) prepared by the American Academy of Orthopedic Surgeons (AAOS) has some advantages in terms of methodology selection and recommendation. Therefore, it is necessary for us to interpret this CPG to speed up the understanding and dissemination of the CPG. The ultimate aims are to: ① strengthen the standardization and understanding of surgical treatment of KOA; ② enhance the understanding of clinicians for this CPG in treating KOA; ③ speed up the development of guideline development methodologies in China; ④ provide methodological guidance for the development of CPG based on the current situation in China.

    Release date:2018-08-14 02:01 Export PDF Favorites Scan
  • 内界膜剥除联合C3F8填充治疗伴后巩膜葡萄肿的高度近视黄斑裂孔视网膜脱离

    Release date:2016-10-21 09:40 Export PDF Favorites Scan
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