Using paired t-test statistical analysis,authors studied the features of hemorrheology in 13 cases of anterior uveitis,16 cases of pan-uveitis,and 15 cases of Behccedil;et' syndrome.The study showed that serous viscocity(at 230 s-1)in anterior uveitis patient group was higher than that of the control group,P<0.02; that blood viscocity at high shear rate(230 s-1)in pan-uneitis patient group was markedly elevated and the difference between patient and control group was sighificant,P<0.005; and that blood viscocity at both high(230 s-1)and low shear rate(5.75 s-1)in Behcet' syndrome grou was elevated,and the differences were significant as compared to the controls(P<0.01,P<0.05).the high blood viscocity in uveitis and Behcet' syndrome patients was analyzed and discussed in the paper.We thought that the treatment for uveitis and Behcet' syndrome should include lowering blood viscocity and improving the plasticity of red blood cells. (Chin J Ocul Fundus Dis,1993,9:70-72)
The experiment was earied out on the a boomen of the whiterats. The epigastric vein wasarterialized by means of anastomcois with the femoral artery, lateral thoracic vein was reserved as aefferent vessel. The changes of hemorheology were mesured after arterialization, and were comparedwith the changes in the normal A-V skin flaps. The levels of platelet, aggreation, blood viscosityand plasma fibrinogen in arterialized vein flape were signmeantly higher than that in A-V flaps. ASa r...
Ankle pump exercise (APE) is one of the basic measures to prevent the formation of deep vein thrombosis, which has been widely recognized for its advantages of simplicity, safety, and ease of perform. However, there is still controversy regarding the frequency, duration, angle, position, and adjunctive exercise of APE. This article will review the hemodynamic and hemorheological effects of APE for the prevention of DVT, the current status of clinical application, and new advances in adjunctive APE, in order to provide methods and guidance for clinical staff.
The present research aims to point out the long-existing defect of analyzing the spectrum diagram only from the perspective of haemodynamics instead of haemorheology. In the light of the theories of haemodynamics and haemorheology, the causes of spectrum diagram formation of carotid artery blood at the rapid and slow flow can be clarified completely and accurately. Four conclusions have been drawn in the end. As long as the velocity gradient is large enough, obvious red blood cells concentrate to the shaft even in the big or bigger blood vessels; the spectrum diagram is the powerful proof of the two phase flow model of blood; the spectrum diagram can be completely and accurately analyzed only by combining haemodynamics with haemorheology; and only when the red blood cells concentrate to the shaft, the big or bigger blood vessels can be regarded as haemogeneous fluid.
OBJECTIVE: To study the hemorheology of island flap after ischemia-reperfusion injury and modulation of dexamethasone. METHODS: Sixty Wister rats were made ischemia-reperfusion injury model, and divided into two groups randomly(Group I: intraperitoneal injection of normal saline 2 ml/kg as control group; Group II: intraperitoneal injection of dexamethasone 5 mg/kg as experimental group). Flap survived areas were measured and neutrophil necrosis numbers in flaps were counted. Erythrocytes and neutrophil hemorheology were observed. RESULTS: Area survived flap in group II was larger than that in group I. Neutrophil necrosis numbers were less in group II than in group I (P lt; 0.05). Whole blood hyposhear viscosity, erythrocyte aggregation, Casson yield stress and nerutrophil adhesion ability were higher in group I than in group II (P lt; 0.05); and the neutrophil deformability was lower in group I than in group II. CONCLUSION: Flap inchemia-reperfusion can increase erythrocyte aggregation index and neutrophil adhesion ability. Dexamethasone can improve these and decrease neutrophil necrosis numbers, so as to prevent flap from ischemia-reperfusion injury.
Objective To explore the effect of xue-shuan-tong(panax notoginsang saponins,PNS)or isovalaemic haemodilution(IHD)and PNS combining IHD treatment on activities of fibrinolysis and hemorrheology in patients with retinal vein occlusion (RVO). Methods Seventy-three patients with RVO were allocated at random to 3 groups which were treated with PNS,IHD and PNS combining IHD.The activities of t-PA and PAI,rheological parameters and visual acuity before and after treatment were observed. Results At the end of treatment,significantly increased activity of t-PA and decrease of PAI was found in combined treatment group and PNS group,but the difference before and after treatment was not significant in IHD group.Furthermore,except the plasma viscosity in IHD group,the other hemorrheological parameters in all the petients of 3 groups revealed to be improving.One month after treatment,the parameters return completely to normal in both PNS and IHD groups; while the whole blood apparent relative viscosity in low shear rate,RBC aggregation and RBC deformability maintained still in lower level,and also the visual acuity resumed better and quicker in combined group. Conclusion Combined treatment of PNS and IHD can both regulate the activity of fibrinolysis and decrease the blood viscosity of patients with RVO for a period of relatively long time and increase the effect of treatment. (Chin J Ocul Fundus Dis,1998,14:7-9)
Objective To evaluate the effects of pseudo-ginseng Tongshu capsule on changes of bloodstream, blood plasma lipid and Fibrin of patients with Brain Infarction. Methods The patients with Brain Infarction were randomly selected, among whom 120 received pseudo-ginseng Tongshu capsule for 3 month and 86 received the routine therapy. Before and after the treatment, change of bloodstream, blood plasma lipid and Fibrin were tested. Results A total of 120 patients were included in the treatment group and 86 in the control group. In the 3rd month, the level of total cholesterol (TC) and Fibrinogen was decreased significantly in the patients with Brain Infarction (Plt;0.05). Conclusion The level of blood plasma lipid and Fibrinogen is decreased significantly in the patients with Brain Infarction who accept pseudoginseng Tongshu capsule.