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Neodoxy of Superficial Thrombophlebitis

Association of human leucocyte antigen-DRB and -DQB alleles with Eales′ disease

Objective To analyze the association of human leucocyte antigen (HLA)-DRB and -DQB alleles with Ealesprime; disease, and to investigate the potential immunogenetics mechanism of Ealesprime; disease. Methods Gene loci of HLA-DRB and -DQB1 alleles were detected by polymerase chain reaction-sequence specific primer (PCR-SSP) in 27 Han-nationality patients with Ealesprime; disease in Northern China and 30 age and sex-matched normal persons as control, then statistics package for social science (SPSS) for Windows ver 13.0 software was used to analyze the distribution features of frequency of HLA-DRB and -DQB1 alleles in the two groups. Results Compared with the control group, the frequency of HLA-DRB104 allele increased obviously in the patients with Ealesprime; disease［odds ratio (OR)=3.20 ，OR 95% confidence interval（CI）=1.00-10.21, and P=0.047］. Simultaneously, no statistically significant difference of the distribution of any other DRB or DQB1 allele between the two groups was found (Pgt;0.05). Conclusions In hannationality people in Northern China, DRB104 is positively associated with Ealesprime; disease, suggesting that DRB104 may confer a major influence on Ealesprime; disease. Turbulence of immune function begotten by infect-agents attack may occur in the individuals with Ealesprime; disease due to the specific hereditary diathesis of HLA, which may cause the occurrence and development of Eales disease. (Chin J Ocul Fundus Dis, 2006, 22: 90-93)

Clinic Effect of Comfeel Transparent Paste on Prevention of Phlebitis with Breast Cancer Who Firstly Used Chemotherapy Treatment after Surgery

目的:观察康惠尔透明贴防治表阿霉素(E--ADM)联合用药致静脉炎的临床效果。方法:将160名第1次大剂量(100mg／m2)静脉滴注表阿霉素的乳腺癌术后患者按床号的单双数随机分为对照组和实验组各80例,静脉穿刺处对照组使用3M透明贴,实验组使用康惠尔透明贴,观察两组患者静脉炎发生率及严重程度。结果:对照组发生静脉炎31例,实验组发生静脉炎9例。两组经秩和检验,W=6.638 P=0.0353。 结论:使用康惠尔透明贴能有效预防表阿霉素联合用药所致的静脉炎,值得临床推广应用。

留置时间与静脉留置针所致静脉炎的相关性研究

目的：探讨留置时间与静脉留置针所致静脉炎的相关性，寻求安全的使用方法。方法：运用静脉炎调查分析量表，对608例患者使用静脉留置针的情况进行调查分析。结果：共有43例患者发生静脉炎，留置时间＞7天组及6～7天组，与其他各组间比较P＜0.05，差异有经计学意义；而其余三组间比较P＞0.05，没有显著性差异。留置时间与静脉炎发生率的相关系数为0.9315。结论：留置时间与静脉留置针所致静脉炎有正相关性，留置时间超过5天后，静脉炎的发生率即显著升高。

LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN THE VITREOUS OF PATIENTS WITH RETINAL VEIN OCCLUSION AND EALES' DISEASE

PURPOSE:To investigate the content of vascular endothelial growth factor (VEGF)in vitreous of patients with retinal vascula'r proliferative diseases. METHODS:The concentration of VEGF in undiluted vitreous samples from patients with retina vein occlusion (RVO) (n=7),Eales disease (n=7)and controls (n=7) was measured by enzyme linked immunosorbent assay (EL1SA). RESULTS:The levels of vitreous VEGF were significantly higher 13 folds in patients with RVO(4.67plusmn;3.38)ng/ml and 5 folds in patients with Eales disease(1.79plusmn;0.44)ng/ml than in controls (0.35plusmn;0.15)ng/ml separately(P＜0. 01). CONCLUSIONS:VEGF might play a part in mediating the neovascularization of retinal vascular diseases. （Chin J Ocul Fundus Dis,1997,13:171-173）

Evident-Based Nursing for a Patient with Grade II Red and Swelling Type Phlebitis

Objective　To formulate a rational adjuvant therapeutic evidence-based nursing plan for a patient with grade II red and swelling type phlebitis. Methods　According to the condition of the patient and using the PICO principle, we put forward clinical problems. Then we comprehensively searched the National Guideline Clearinghouse (NGC), ACP Journal Club, The Cochrane Library, DARE, PubMed, MEDLINE, CNKI and Google Scholar from 2000 to 2012. Relevant clinical guidelines, evidence summaries, systematic reviews/ meta-analyses, randomized controlled trials (RCTs), and high quality reviews on adjuvant therapy of grade II red and swelling type phlebitis were collected and their authenticity, importance and applicability were evaluated. Results　One systematic review, four meta-analyses, five RCTs, and one review were totally included. According to current evidence as well as the patient’s clinical conditions and preference, a comprehensive and effective adjuvant therapeutic and nursing programme was given to the patient. For grade II red and swelling type phlebitis with blisters and severe pain, paretic infusion should be immediately stopped on the lesion-side limb, and venous indwelling needle should be extracted. Then, mucopolysaccharide polysulfate cream should be applied on the skin impaired by vein inflammation, and the local area should be gently massaged for 3 min, twice daily (once in the morning and evening, respectively). After four-day treatment and nursing care, the patient with phlebitis had already recovered. Conclusion　Evidence-based medicine approaches could help us develop comprehensive therapeutic plans for patients which promote recovery of patients with phlebitis, alleviate pain, improve health, and increasepatients’ quality of life.

钆喷酸葡胺注射液导致迟发型血栓性静脉炎的护理二例

海绵窦血栓静脉炎

报道6例海绵窦血栓静脉炎，5例经治疗眼症状及全身症状消失，1例死亡。感染为首先要原因，多在1～3个月发病，可能与气候寒冷易感冒有关。因海绵窦解剖特点，体征较早表现于眼部，幼年者易患，故有感染性疾病者应警惕发生本病，视力损害严重，应特别重视。 （中华眼底病杂志，1993，9：106-107）

冠心病灸治疗静脉留置针所致静脉炎

【摘要】　目的　将冠心病灸与硫酸镁外敷治疗静脉留置针所致静脉炎的疗效进行比较和分析。　方法　2008年6月－2010年6月，将86例静脉炎患者随机分为两组，观察组用冠心病灸贴于患处；对照组用50.0%硫酸镁湿敷治疗，3～5 d后观察并比较两组疗效。　结果　观察组有效率为90.8%，对照组有效率为61.8%，两组差异有统计学意义（Plt;0.05）；观察组疼痛缓解时间、红肿消失疗效明显优于对照组。　结论　冠心病灸治疗静脉留置针所致静脉炎疗效优于硫酸镁湿敷治疗，无不良反应，而且经济、方便，值得临床推广。

水胶体敷料预防大量输液所致静脉炎的效果研究

目的:观察水胶体敷料外敷对预防大量静脉输液(其中含刺激性的药物)引起静脉炎的效果。方法:将80 例女性胰腺炎患者随机分为对照组(40 例)和试验组(40 例),两组均采用常规留置针穿刺,试验组在穿刺成功固定后,在距静脉穿刺点2 cm处沿血管走向用4 cm× 6 cm水胶体敷料贴于皮肤表面。对照组未用水胶体敷料,两组留置针保留时间均为3 天。结果:对照组与试验组Ⅰ级静脉炎发病率分别为72.5% 和22.5%,差异有统计学意义(P lt; 0.05)。结论:水胶体敷料外敷,能有效预防大量输液所致静脉炎的发生,减轻患者痛苦。