目的:探讨行气管切开术抢救成功的重型颅脑损伤及高血压脑出血患者直接除管的安全性和可行性。方法:在507监护仪行SPO2监测和严密观察下,不经过试阻管而直接将气管套管拔除。结果:本组除1例患者因带管时间长,切口周围气管内炎性肉芽生长而重新插管外,其余患者呼吸平稳,呼吸道通畅,无呼吸急促、呛咳、紫绀及SPO2降低。结论:此法避免了传统除管前试阻管的繁锁和由阻管而引起的多种不良反应,有临床实用价值。
Objective To discuss the treatment of craniocerebral injuries caused by earthquake. Methods Retrospective analysis of clinical information for 256 patients with craniocerebral injury caused by an earthquake. Results The ‘Classification and Treatment’ was applied to the patients, whether or not they were operated on. A total of 146 patients were cured, 68 improved, 24 remained dependent on the care of others, and 8 died. The mortality rate was 3.13%. Conclusion Applying the ‘Classification and Treatment’ to patients with craniocerebral injury following an earthquake supported the use of medical resources and was associated with a low rate of death and disability.
ObjectiveTo investigate the effects of health education pathway intervention on the mental status and coping capacity in family members of brain injury patients receiving surgery. MethodsOne hundred and eighty-eight family members were randomly divided into control group (n=93) and intervention group (n=95) between September 2013 and October 2014. The control group received conventional health education only, while the intervention group was given health education pathway intervention. The mental status and coping capacity of family members in the two groups on admission and at discharge were surveyed and compared based on symptom checklist 90 (SCL-90) and coping styles questionnaire (CSQ). The hospitalization stay and expenditure and the satisfaction degree were also compared. ResultsThere was no significant differences in mental status and coping capacity in family members between the two groups on admission (P > 0.05). After health education pathway intervention, the positive rate of SCL-90 in the control group was significantly higher than that in the intervention group, and the total score and score for each factor were also obviously higher (P < 0.05). As for coping capacity, the scores of self-blaming, avoidance, fancy and rationalization of CSQ in the control group were significantly higher than those in the intervention group, and the scores of appealing help and resolving problems were obviously lower (P < 0.05). Furthermore, the hospitalization stay and expenditure were significantly shorter or lower in the intervention group than those in the control group, and the satisfaction degree on nursing service was obviously higher (P < 0.05). ConclusionThe health education pathway intervention can greatly improve mental status and coping capacity in family members of brain injury patients.
目的:分析重型颅脑损伤患者早期进入ICU进行监护和治疗对预后的影响。方法: 将重型颅脑损伤患者根据是否直接进入ICU分为研究组和对照组,评价3月后患者神经功能和死亡率。结果: 与对照组比较,研究组死亡率更低,3月后ADL分级法生存质量良好率也显著更高。结论: 重型颅脑损伤患者早期进入ICU监护和治疗,可降低术后病死率,改善生存质量。
ObjectiveTo explore a method of three-dimensional (3D) printing technology for preparation of personalized rat brain tissue cavity scaffolds so as to lay the foundation for the repair of traumatic brain injury (TBI) with tissue engineered customized cavity scaffolds. MethodsFive male Sprague Dawley rats[weighing (300±10) g] were induced to TBI models by electric controlled cortical impactor. Mimics software was used to reconstruct the surface profile of the damaged cavity based on the MRI data, computer aided design to construct the internal structure. Then collagen-chitosan composite was prepared for 3D bioprinter of bionic brain cavity scaffold. ResultsMRI scans showed the changes of brain tissue injury in the injured side, and the position of the cavity was limited to the right side of the rat brain cortex. The 3D model of personalized cavity containing the internal structure was successfully constructed, and cavity scaffolds were prepared by 3D printing technology. The external contour of cavity scaffolds was similar to that of the injured zone in the rat TBI; the inner positive crossing structure arranged in order, and the pore connectivity was good. ConclusionCombined with 3D reconstruction based on MRI data, the appearance of cavity scaffolds by 3D printing technology is similar to that of injured cavity of rat brain tissue, and internal positive cross structure can simulate the topological structure of the extracellular matrix, and printing materials are collagen-chitosan complexes having good biocompatibility, so it will provide a new method for customized cavity scaffolds to repair brain tissue cavity after TBI.
Objectives To assess the efficacy and safety of standard trauma craniectomy (STC), compared with limited craniectomy (LC) for severe traumatic brain injury (sTBI) with refractory intracranial hypertension. Methods We searched the Cochrane Central Register of Controlled Trials-Central (The Cochrane Library Issue 3, 2008), MEDLINE (1966 to October 2008), EMbase (1984 to October 2008), CMB-disc (1979 to October 2006) and CNKI (1979 to October 2008) for completed studies, as well as clinical trial registries for ongoing studies and completed studies with unpublished data. The reference of included studies and relevant supplement or conference abstracts were handsearched. The search results were extracted, and then the quality of included studies was assessed using RevMan 5.0. Meta-analysis was conducted if the data was similar enough. Results Two randomized controlled trials (RCTs) involving 716 participants were identified. Compared with the LC group, the STC group had statistically significant, more favorable outcome on the basis of the Glasgow Outcome Scale, using measures such as mortality, efficiency, and survival, compared with those of LC group, which had statistic difference. The mean ICP fell more rapidly and to a lower level in the STC group than in the LC group. There was no statistically significant difference on the incidence of postoperative complications, including delayed hematoma, incision cerebrospinal fluid fistula, encephalomyelocele, traumatic epilepsy, and intracranial infection as well. Conclusion The efficacy of STC is superior to LC for severe TBI with refractory intracranial hypertension resulting from unilateral frontotemporoparietal contusion with or without intracerebral or subdural hematoma.