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find Keyword "食管癌" 367 results
  • Feasibility study of removal of gastric tube for gastrointestinal decompression after minimally invasive esophageal cancer surgery

    ObjectiveTo explore the feasibility of decompression without gastric tube after minimally invasive esophageal cancer surgery.MethodsSeventy-two patients who underwent minimally invasive esophageal cancer resection at the Department of Thoracic Surgery, The Second Affiliated Hospital of Harbin Medical University from 2016 to 2018 were selected as a trial group including 68 males and 4 females with an average age of 58.5±7.9 years, who did not use gastric tube for gastrointestinal decompression after surgery. Seventy patients who underwent the same operation from 2013 to 2015 were selected as the control group, including 68 males and 2 females, with an average age of 59.1±6.9 years, who were indwelled with gastric tube for decompression after surgery. We observed and compared the intraoperative and postoperative indicators and complications of the two groups.ResultsThere were no significant differences between the two groups in operation time, intraoperative blood loss, postoperative level of serum albumin, postoperative nasal jejunal nutrition, whether to enter the ICU postoperatively, death within 30 days after surgery, anastomotic leakage, lung infection, vomiting, bloating or hoarseness (P>0.05). No gastroparesis occurred in either group. Compared with the control group, the recovery time of the bowel sounds and the first exhaust time after the indwelling in the trial group were significantly shorter, and the total hospitalization cost, the incidence of nausea, sore throat, cough, foreign body sensation and sputum difficulty were significantly lower (P<0.05).ConclusionIt is feasible to remove the gastric tube for gastrointestinal decompression after minimally invasive esophageal cancer surgery, which will not increase the incidence of postoperative complications, instead, accelerate the postoperative recovery of patients.

    Release date:2020-07-30 02:16 Export PDF Favorites Scan
  • RECONSTRUCTION OF ESOPHAGUS BY MICROSURGICAL TECHNIQUE IN FORTY FIVE CASES

    Reconstruction and repair of atresia or defect of the upper portion of esophagus is difficult. From November 1980 to December 1997, forth-five cases, consisting 35 males and 10 females, were treated with microsurgical technique. The 45 patients fell into the following groups as esophageal atresia of various causes in 21 cases, anastomotic fistula or stenosis following reconstruction of esophagus in 7 cases and late carcinoma of esophagus in 17 cases. The types of reconstruction consisted of transfer of free jejunum with its lower portion carrying a vascular pedicle in 24 cases, free transfer of jejunal graft in 15 cases, free vascularized jejunal graft in 2 cases and free vascularized tubular skin graft in 4 cases. After a follow-up of 6-19 months besides eight cases died from late esophageal carcinoma, thirty-seven cases were survived and could take food by mouth. All of the benign cases could return to work. In patients having late esophageal carcinoma, the operative procedure could improve the life quality and facilitate chemotherapy and radiotherapy.

    Release date:2016-09-01 11:07 Export PDF Favorites Scan
  • Diagnosis and treatment of esophageal diseases by video-assisted thoracoscopic surgery

    Mini-invasive video-assisted thoracoscopic surgery (VATS) has been employed in diagnosis and treatment of esophageal diseases for about 10 years. The potential advantages of VATS over thoracotomy are reduction of chest pain just after the operation and in the long run, lower incidence of postoperative respiratory complications, and reduction of aesthetic sequelae. Thoracoscopic staging of esophageal cancer is to evaluate the invasion and metastasis of cancer, which is helpful for better selection of patients for appropriate treatment .Operation of esophageal cancer with VATS is prescribed mainly in the early stage of carcinoma, but it’s application is restricted due to the multiple sites of operation and complexity of procedures. VATS for benign esophageal diseases such as esophageal leiomyoma and achalasia is becoming the preferable choice of operation in qualified medical centers.

    Release date:2016-08-30 06:28 Export PDF Favorites Scan
  • P53蛋白与增殖细胞核抗原在食管、贲门癌中的表达及临床意义

    目的 为了探讨P53蛋白和增殖细胞核抗原在食管、贲门癌中的表达及其临床意义.方法 应用SP免疫组织化学法,研究了40例食管鳞状细胞癌和28例贲门腺癌P53蛋白的表达及其与细胞增殖活性、淋巴结转移的关系.结果 食管癌与贲门癌P53蛋白阳性率分别是60%和57.1%.53.3%的癌旁组织中有P53蛋白过度表达.食管癌有淋巴结转移者P53蛋白阳性率和细胞增殖活性较无转移者明显增高(P<0.01),说明p53基因的突变以及导致细胞恶性增殖不仅与食管、贲门癌的发生有关,而且在其淋巴结转移中也起重要作用.结论 检测P53蛋白和细胞增殖核抗原对食管、贲门癌的早期诊断及判断肿瘤的恶性程度,评估预后有较高的参考价值.

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • 食管癌合并胸腺瘤伴重症肌无力一例

    Release date:2016-08-30 05:46 Export PDF Favorites Scan
  • 胸腹腔镜下食管次全切除、区域淋巴结清扫及食管-胃颈部吻合术视频要点

    Release date:2020-06-29 08:13 Export PDF Favorites Scan
  • 碘-125粒子支架植入治疗晚期食管癌

    目的 探讨附有放射碘125(125I)粒子的机织式支架植入治疗晚期食管癌的效果, 总结临床经验,以期为晚期食管癌患者的合理治疗提供临床依据。 方法 37例晚期食管癌患者应用附有125I粒子的机织式支架植入治疗,术中、术后观察随访支架植入成功率及并发症的发生率, 比较术前与术后3个月食管病变长度和白细胞计数的变化。 结果 37例患者手术过程顺利,支架植入成功率均为100%,仅3例患者胸部有明显疼痛不适感,经对症处理后缓解;随访6个月,随访33例,失访2例,死亡1例,因年龄偏大,体质较弱死亡。术后3个月,吞咽困难缓解率为100%,治疗后较治疗前食管病变长度明显缩小(Plt;0.05),而白细胞计数的变化差异无统计学意义 (Pgt;0.05)。 结论 附有125I粒子的机织式支架能明显改善吞咽困难症状,还可对肿瘤进行组织间放疗, 明显改善患者术后的生存质量。

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
  • Clinical Study of Gastroesophageal Reflux and Gastric Emptying after Esophagectomy with Gastric Replacement Through Esophageal Bed

    Abstract: Objective To evaluate the effect on gastroesophageal reflux and gastric emptying in the different route of gastroesophageal anastomosis objectively after esophagectomy for patients with midesophageal carcinoma. Methods Forty patients with midesophageal carcinoma were randomly divided into two groups. Esophageal bed group (n=20): the gastroesophageal anastomosis were performed while the stomach were pulled on through the esophageal bed after esophagectomy; endothoracic group (n=20): gastroesophageal anastomosis were performed while the stomach were pulled on in the thoracic cavity. Ten persons had no disease of digestive system and healthy volunteers were recruited as normal control group. 24-hour esophageal pH monitoring and radioisotope gastric emptying checkup were carried out in all experimental subjects 3 months after operation, so as to observe the changes of gastroesophageal reflux and gastric emptying. Results All of the patients’s operation were success. And no anastomotic leakage and no anastomotic stenosis. Three months after operation, the patients in both operation groups were with different level of reflux. DeMeester total appraise score, the times of regurgitation of gastric juice in 24h, gt;5 min reflux frequency, the longest time of keep reflux, pHlt;4.00 total time and pHlt;4.00 of total time percent, these targets in both operation groups were higher than those in control group (Plt;0.01) DeMeester total appraise score, the times of regurgitation of gastric juice in 24 hours, the longest time of keeping reflux, pHlt;4.00 of total time and pHlt;4.00 of total time percent in esophageal bed group were lower than those in endothoracic group(Plt;0.01). The recent period of gastric emptying percentage (GE) in both operative groups were lower than that in normal control group. GE in esophageal bed group experimental meal in the stomach after entering the 30,60,90,120,180 and 240 min were higher than those in endothoracic group. Conclusion After the operation of esophagogastric anastomosis through esophageal bed in upper aortic site,gastroesophageal reflux and delayed gastric emptying exist objectively, However, the technique is superior to the traditional technique to reduce the extent of gastroesophageal reflux and delayed gastric emptying, its mechanism might be the result of mechanical factors.

    Release date:2016-08-30 06:16 Export PDF Favorites Scan
  • 机械吻合器在胸内消化道重建术中的应用

    目的 评价消化道管型吻合器在食管癌和贲门癌手术中的应用价值。 方法 2001年8月-2008年9月期间应用管型吻合器对192例食管、贲门癌切除后进行机械吻合,其中男124例,女68例;食管癌135例,贲门癌57例;食管胃弓上吻合43例,弓下吻合149例。 结果 术后出现吻合口瘘2例(1.04%), 吻合口狭窄4例(2.08%),吻合口少量出血3 例(1.56%),胃食管返流13例(6.77%)。 结论 在上消化道重建手术中应用消化道管型吻合器安全可靠,机械吻合是减少术后吻合口瘘等并发症的有效技术。

    Release date:2016-09-08 09:47 Export PDF Favorites Scan
  • 胸下段食管癌术后放射治疗的范围

    食管癌恶性程度高,全球范围内食管癌死亡率居恶性肿瘤的第 6 位。大多数食管癌的治疗首选手术切除,但根治术后复发率仍较高,局部复发是治疗失败的主要原因,术后预防性放射治疗可提高局部控制率。然而,放射治疗靶区的范围仍存在争议,尤其是胸下段食管癌术后患者行放射治疗时是否需包含锁骨上区淋巴结照射。部分学者认为增加双侧锁骨上区淋巴结照射无意义,但有更多的研究显示增加锁骨上区淋巴结照射可以减少锁骨上区复发率,术后放射治疗时需重点考虑。

    Release date:2017-06-22 02:01 Export PDF Favorites Scan
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