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The Comparison of the Effect and Nursing between Ordinary Therapy and WLGY 801 Liver Disease Therapy Instrument in Patients with the Virus Hepatitis

目的:评价电脑肝病治疗仪治疗病毒性肝炎的疗效及不良反应。方法:将116例病毒性肝炎患者随机分为治疗组及对照组,治疗组60例,对照组56例。两组均以抗炎、保肝、降酶、退黄、对症为治则。治疗组加用电脑肝病仪治疗，每日一次。结果:治疗组在消化道症状改善方面有效率950%,黄疸消退方面有效率902%。谷丙转氨酶恢复方面有效率85%。而对照组分别为8214%、6786%和7143%。结论:电脑肝病治疗仪治疗肝病能迅速改善消化道症状,有效降低黄疸、转氨酶,未见明显不良反应。

Eotaxin Expression of Airway Smooth Muscle Cells Induced by Sensitized Serum in Rats

Objective To observe the eotaxin expression of rat airway smooth muscle cells ( ASMCs) induced by serum from asthmatic rats, and explore the possible mechanism. Methods ASMCs isolated fromrat tracheas were cultured in vivo. Then they were treated with serum from asthmatic rats, or treated with serum and dexamethasone simultaneously. The level of eotaxin protein in supernatant and eotaxin mRNA in ASMCs were measured by ELISA and reverse transcription-polymerase chain reaction. The expression of cAMP in ASMCs was examined by radioimmunoassay. Results After the treatment with sensitized serum, the eotaxin level in supernatant and mRNA expression in ASMCs were significantly higher [ ( 107. 09 ±7. 12) ng/L vs. ( 0. 63 ±0. 56) ng/L, P lt; 0. 05; 1. 39 ±0. 04 vs. 0. 05 ±0. 01, P lt;0. 05] , and the level of cAMP in ASMCs was significantly lower compared with the control group [ ( 17. 58 ±3. 62) ng/L vs. ( 32. 39 ±3. 36) ng/L, P lt; 0. 05] . After intervened by the sensitized serum and dexamethasone simultaneously, the protein and mRNA expressions of eotaxin were lower compared with those intervened by sensitized serumalone [ ( 64. 18 ±4. 04) ng/L and 0. 77 ±0. 19] . The level of eotaxin in supernatant was negatively correlated with cAMP level in ASMCs ( r = - 0. 788, P lt; 0. 01) . Conclusions There is anautocrine function in ASMCs as inflammatory cells after stimulation with sensitized serum. Eotaxin may play an important roll in the pathogenesis of asthma via a cAMP-dependent pathway.

嗜酸性肉芽肿性多血管炎 186 例临床荟萃分析

目的 总结嗜酸性肉芽肿性多血管炎的临床特征。 方法 以“嗜酸性肉芽肿性多血管炎”、“变应性肉芽肿性血管炎”、“Churg-Strauss 综合征”为检索词，通过中国医院知识数据库（CHKD）对 2017 年 1 月以前发表的例数达10 例以上的中文文献进行检索，并汇总分析。 结果 符合嗜酸性肉芽肿性多血管炎诊断的病例 186 例，以呼吸系统受累最常见（73.7%），神经系统（68.3%）、皮肤损害（60.2%）、泌尿系统（42.5%）受累也较为常见。肾脏受累较轻，最常见实验室检查异常为血嗜酸性粒细胞增高（90.8%）。 结论 嗜酸性肉芽肿性多血管炎临床表现多样，早期识别困难，临床医生须加强认识，提高警惕，争取早期诊断，改善预后。

小剂量糖皮质激素治疗急性狼疮性肺炎一例

The Clinical Efficacy of Specially-made “Yinchen Chaiping Tang” Decoction in Treating Chronic Hepatitis B

目的　观察茵陈柴平汤治疗重度慢性乙型肝炎的疗效及不良反应。 方法　2009年3月－2010年3月，选择采用茵陈柴平汤联合常规保肝药物治疗50例重度慢性乙型肝炎患者（治疗组），并与50例仅用常规保肝药物治疗的重度慢性乙型肝炎患者（对照组）进行比较，观察治疗2、4周时的临床症状、肝功能及凝血酶原活动度等指标的变化。 结果　治疗2、4周时，治疗组在肝功能及凝血酶原活动度等指标均有显著改善，无严重不良反应；4周时，治疗组的症状缓解率（84%）明显高于对照组（66%）；其总有效率（96%）亦高于对照组（80%）。 结论　茵陈柴平汤治疗重度慢性乙型肝炎具有较好的临床疗效，且无严重不良反应。

阑尾重复畸形合并急性阑尾炎1例报告

A deep transfer learning approach for cross-subject recognition of mental tasks based on functional near-infrared spectroscopy

In the field of brain-computer interfaces (BCIs) based on functional near-infrared spectroscopy (fNIRS), traditional subject-specific decoding methods suffer from the limitations of long calibration time and low cross-subject generalizability, which restricts the promotion and application of BCI systems in daily life and clinic. To address the above dilemma, this study proposes a novel deep transfer learning approach that combines the revised inception-residual network (rIRN) model and the model-based transfer learning (TL) strategy, referred to as TL-rIRN. This study performed cross-subject recognition experiments on mental arithmetic (MA) and mental singing (MS) tasks to validate the effectiveness and superiority of the TL-rIRN approach. The results show that the TL-rIRN significantly shortens the calibration time, reduces the training time of the target model and the consumption of computational resources, and dramatically enhances the cross-subject decoding performance compared to subject-specific decoding methods and other deep transfer learning methods. To sum up, this study provides a basis for the selection of cross-subject, cross-task, and real-time decoding algorithms for fNIRS-BCI systems, which has potential applications in constructing a convenient and universal BCI system.

Pathogenesis of Acute Pancreatitis During Pregnancy and The Standardization of Diagnosis and Treatment

ObjectiveTo explore the pathogenesis of acute pancreatitis during pregnancy, differential diagnosis, and standardized treatment. MethodsThe related literatures at home and abroad in recent years were reviewed, and the progress of pathogenesis and treatment of acute pancreatitis during pregnancy were summarized. ResultsThe common cause of acute pancreatitis during pregnancy include biliary system diseases, hyperlipidemia, hyperparathyroidism, the direct effect of pregnancy on the pancreas, etc. According to the different pathogenic factors of acute pancreatitis during pregnancy, the laparoscopic cholecystectomy (LC), endoscopic retrograde cholangiopancreatography (ERCP), low-fat diet combined with Omega-3 fatty acids, parathyroid adenoma resection, or terminal pregnancy could be use. ConclusionAcute pancreatitis during pregnancy is dangerous, the cause, general condition of patients, and the growth of fetus should be give full consideration, and the diagnosis and treatment are standardized.

慢传输型便秘的外科治疗

Timing of surgery and exercise training of hip fracture in the elderly

Hip fracture in the elderly is a disease with a high mortality rate and a high complication rate. Its main treatment method is surgery. The concept of enhanced recovery after surgery runs through the perioperative period of elderly patients with hip fracture. Elderly patients with hip fracture should be scheduled for surgery as soon as possible after admission to enhance postoperative functional recovery. Preoperative ambulation and postoperative exercise can reduce postoperative complications and mortality, shorten the length of hospital stay, and promote functional recovery.