【摘要】 目的 探讨指导性强化作业疗法对脑卒中患者上肢运动功能障碍的疗效，旨在提高患者的生活质量。 方法 2007年6月-2009年6月将68例脑卒中偏瘫患者随机分成治疗组及对照组。治疗组进行指导性强化作业疗法，对照组采用传统康复训练。分别于治疗前、治疗后和治疗后1、3个月应用MAL和Bathel指数对其进行评定。 结果 两组MAL评分及Bathel指数在治疗后均有所提高，治疗组在治疗后1、3个月的MAL评分及Bathel指数较治疗前增加，有统计学意义（Plt;0.05）；对照组无差异。治疗后1、3个月，两组MAL评分及Bathel指数比较有统计学意义（Plt;0.05）。 结论 指导性强化作业疗法作为一种新型的康复治疗技术，能够改善患者上肢运动功能及日常生活能力，提高生活质量，具有较高的临床应用价值。【Abstract】 Objective To explore the efficacy of guiding intensified occupational therapy for ischemic stroke patients with upper motor dysfunction, aiming at improving the quality life of the patients. Methods From June 2007 to June 2009, sixty-eight patients with stroke were randomly divided into treatment group and control group. Treatment group was treated with guiding strengthen occupational therapy and control group with trandional therapy. The MAL and the Bathel index were used to evaluate before treatment, after treatment and 3 months after treatment respectively. Results The MAL score and Bathel index were improved after treatment. The MAL score and Bathel index of the treatment group immediately and in 3 months after treatment increased greatly, and there were statistical significance (Plt;0.05). There was no difference in the MAL score and Bathel index in the control group before and after treatment. The MAL score and Bathel index of two groups were statistically significant after 3 months treatment (Plt;0.05). Conclusion Guiding intensified occupational therapy as a new kind of rehabilitation techniques, can improve the function of upper movement and daily life, and improve the quality life. It had high value of clinical applications.