Objective To review the changes of gut microbiota after bariatric surgery and the related mechanisms of improving metabolism. Method Domestic and international literatures in recent ten years on the changes of gut microbiota in bariatric surgery and the mechanisms of improving metabolism were collated and summarized. Result The common bariatric procedures performed to date were vertical sleeve gastrectomy (VSG) and laparoscopic Roux-en-Y gastric bypass (RYGB). The changes of gut microbiota vary in different surgical procedures, which were related to the changes of diet habits, gastrointestinal anatomy, gastrointestinal hormone levels and metabolic complications. The gut microbiota might improve the body metabolism by regulating the levels of short chain fatty acids, branched chain amino acids and bacterial endotoxin in the intestinal lumen. Conclusions Significant changes are found in gut microbiota after bariatric surgery, which may be involved in the improvement of body metabolism by regulating the level of bacterial endotoxin and microbial metabolite. However, more in-depth mechanisms need to be further clarified.
[Abstract]Acute cardiac tamponade after thoracoscopic lobectomy is extremely rare and highly lethal once it occurs. This paper reports a case of a 64-year-old male with preoperative hypertension and coronary heart disease who underwent video-assisted thoracoscopic right upper lung wedge resection for early-stage lung adenocarcinoma. Three hours postoperatively, he suddenly developed hypotension and loss of consciousness. Ultrasound indicated a large amount of pericardial effusion, suggesting cardiac tamponade. Despite emergency pericardiocentesis, his hemodynamics did not improve, and the patient went into cardiac arrest. Subsequent veno-arterial extracorporeal membrane oxygenation was performed to support systemic circulation, and emergency thoracotomy was carried out. During the surgery, a needle-like tear in the anterior wall of the ascending aorta was found, corresponding exactly to a prominent staple at the lung resection margin, suggesting a stapler malfunction. After vascular repair, the patient recovered smoothly and was discharged. This case suggests that during lung resection, great attention should be paid to the integrity of staples and anatomical variations of large vessels, and vigilance is needed for rare but potentially fatal stapler-related complications.