Objective To explore the clinical value of Persyst automatic detection of spike waves in adult patients with temporal lobe epilepsy. Methods EEG recordings were continuously concluded from the Epilepsy Unit of the First Affiliated Hospital of Soochow University during 2019.1.1 to 2019.12.31. Two EEG experts certified by the Chinese Anti-Epileptic Association marked interictal epileptic discharge in the long-time electroencephalogram that meet the criteria. Consistent results of the two experts were seen as the "golden standard". The sensitivity and false positive rates were calculated compared with the automatic test results of Persyst version 11, 13 and 14. Results 7 cases were included, each with a recording time of 24~25 hours and a total of 169 hours. Two expert readers achieved the consistency of 43.09%. Spike waves detected automatically were much more than manually. The sensitivity was as high as 62.26%, 77.0% and 67.28%. The lowest false positive rate was 0.37/min, 0.85/min and 0.46/min respectively. Automatic analysis achieved an average workload reduction of 14.59%~37.05%. Conclusions Persyst automatic spike detection has the acceptable sensitivity and false positive rate. It differs from versions and need to be further combined with expert readers.Less workload and accuracy can be balanced by setting reasonable perception parameter.
Objective To preliminarily analyse the phenomenon of the first seizure in patients with epilepsy while driving a motor vehicle, and discuss its harms and possible coping strategies. Methods The first seizure while driving a motor vehicle was investigated among epilepsy patients who attended the First Affiliated Hospital of Soochow University from June 2020 to March 2023. Results A total of five patients had their first seizure while driving a motor vehicle, all causing traffic accidents. One patient had a generalized tonic-clonic seizure with a first epileptic seizure, two had focal seizures with impaired consciousness that progressed to generalized seizures, and two had focal seizures with impaired awareness. One of the patients caused a fatal traffic accident, leading to the death of another person who riding the electric bicycle. In this case, the patient's driving license was revoked. The other four patients continued to drive after the first seizure. One patient terminated driving 5 months after the diagnosis of epilepsy. Two patients drove less since then, and one patient continued driving as before. Two patients experienced seizures again while driving, and one of them coincidentally had his second seizure while driving. Conclusions The first seizure while driving may not be uncommon, reflecting the severity of epilepsy and driving, in which traffic accidents can be fatal. People with epilepsy are currently prohibited from driving in China. After the first seizure, patients should immediately stop driving and go to see an epileptologist, avoiding further endangering themselves and the public.